Rchr
J-GLOBAL ID：200901058200510689   Update date: Apr. 22, 2024

Takaori-Kondo Akifumi

タカオリ アキフミ | Takaori-Kondo Akifumi
Affiliation and department：
Kyoto University Graduate School of Medicine, Graduate School of Medicine Medicine

About Kyoto University Graduate School of Medicine, Graduate School of Medicine Medicine


Job title： Lecturer
Research field  (4)： Genomics ,  Tumor biology ,  Hematology and oncology ,  Virology
Research keywords  (21)： hematopoietic stem cell transplantation ,  cancer immunotherapy ,  cancer cell biology ,  iPS cell ,  DNA repair ,  cancer genomics ,  hematooncology ,  HTLV-1 ,  ユビキチン ,  APOBEC ,  AIDS ,  HIV-1 ,  レトロウイルス ,  ubiquitin ,  Cytidine deaminase ,  APOBEC ,  Lentiviral Vector ,  Gene Therapy ,  AIDS ,  HIV-1 ,  Retrovirus
Research theme for competitive and other funds  (24)：
  • 2022 - 2025 COVID-19における赤血球結合抗体産生病態解明と細胞外小胞を応用した病態制御
  • 2019 - 2022 Optimizing immunomodulation of hematopoietic stem cell transplantation focusing on allelic polymorphisms of KIRs
  • 2019 - 2022 APOBEC3B-induced genome mutations and its contribution to clonal evolution in cancers
  • 2018 - 2021 Comprehensive enhancer analysis and molecular pathogenesis of leukemia using our novel technology
  • 2014 - 2018 Elucidation of the mechanism by which virus inhibits the function of human anti-virus enzymes and molecular basis of drug discovery
Show all
Papers (413)：
  • Hiroki Futatsusako, Rina Hashimoto, Masaki Yamamoto, Jumpei Ito, Yasufumi Matsumura, Hajime Yoshifuji, Kotaro Shirakawa, Akifumi Takaori-Kondo, Kei Sato, Miki Nagao, et al. Longitudinal analysis of genomic mutations in SARS-CoV-2 isolates from persistent COVID-19 patient. iScience. 2024. 27. 5. 109597-109597
  • Naokazu Nakamura, Nobuyoshi Arima, Teruhito Takakuwa, Satoshi Yoshioka, Kazunori Imada, Kentaro Fukushima, Masaaki Hotta, Shin-Ichi Fuchida, Junya Kanda, Nobuhiko Uoshima, et al. Efficacy of elotuzumab for multiple myeloma deteriorates after daratumumab: a multicenter retrospective study. Annals of hematology. 2024
  • Naokazu Nakamura, Tomoyasu Jo, Yasuyuki Arai, Toshio Kitawaki, Momoko Nishikori, Chisaki Mizumoto, Junya Kanda, Kouhei Yamashita, Miki Nagao, Akifumi Takaori-Kondo. Clinical impact of CRS on prolonged hematotoxicity after CAR-T cell therapy: KyoTox a-score, a novel prediction model. Transplantation and cellular therapy. 2024
  • Yuuka Masuda, Hesham Nasser, Jiri Zahradnik, Shuya Mitoma, Ryo Shimizu, Kayoko Nagata, Akifumi Takaori-Kondo, Gideon Schreiber, Kotaro Shirakawa, Akatsuki Saito, et al. Characterization of the evolutionary and virological aspects of mutations in the receptor binding motif of the SARS-CoV-2 spike protein. Frontiers in Virology. 2023. 3
  • Keisuke Kamba, Li Wan, Satoru Unzai, Ryo Morishita, Akifumi Takaori-Kondo, Takashi Nagata, Masato Katahira. Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway. Biophysical journal. 2023
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MISC (261)：
  • Yusuke Kosugi, Yu Kaku, Alfredo A. Hinay, Ziyi Guo, Keiya Uriu, Minoru Kihara, Fumitake Saito, Yoshifumi Uwamino, Jin Kuramochi, Kotaro Shirakawa, et al. Antiviral humoral immunity against SARS-CoV-2 omicron subvariants induced by XBB.1.5 monovalent vaccine in infection-naive and XBB-infected individuals. The Lancet Infectious Diseases. 2024. 24. 3. e147-e148
  • June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi, et al. Amplified EPOR/JAK2 genes definea unique subtype of acute erythroid leukemia. CANCER RESEARCH. 2022. 82. 12
  • 神庭圭佑, WAN Li, WAN Li, 雲財悟, 森下了, 高折晃史, 永田崇, 永田崇, 片平正人, 片平正人. Additive effect of the interactions between the components of HIV-1-Vif: E3 ubiquitin ligase and human APOBEC3G may elevate the antiviral activity of APOBEC3G. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • 神庭圭佑, 雲財悟, 森下了, 高折晃史, 永田崇, 永田崇, 片平正人, 片平正人. HIV-1Vifと宿主タンパク質の五者複合体による抗ウイルス因子APOBEC3Gの脱アミノ化活性阻害の分子機構の解明. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
  • June Takeda, Kenichi Yoshida, Masahiro Marshall Nakagawa, Yasuhito Nannya, Akinori Yoda, Daisuke Morishita, Ryunosuke Saiki, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, et al. EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia. BLOOD. 2021. 138
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Works (1)：
  • HIV-1 Vifを標的とした新規抗HIV-1薬の開発
    2004 -
Education (4)：
  • - 1994 Kyoto University
  • - 1994 Kyoto University Graduate School, Division of Medicine
  • - 1986 Kyoto University Faculty of Medicine
  • - 1986 Kyoto University Faculty of Medicine
Professional career (1)：
  • Doctor (Medicine) (Kyoto University)
Work history (3)：
  • 2010/07 - 現在 Graduate School of Medicine, Kyoto University professor
  • 2008 - - 京都大学医学研究科 講師
  • 2000 - - 京都大学医学研究科 助手
Committee career (5)：
  • 2019/07 - 現在 Scientific Reports -
  • 2005/10 - 現在 - -
  • 2016/10 - -
  • 2010/06 - - -
  • 2009/01 - - -
Awards (2)：
  • 1994 - 日本血液学会奨励賞
  • 1994 - The Japanese Society of Hematology, Young Investigator Award
Association Membership(s) (17)：
日本内科学会 ,  日本ウイルス学会 ,  米国細胞生物学会(The American Society for Cell Biology) ,  日本エイズ学会 ,  日本免疫学会 ,  日本癌学会 ,  日本血液学会 ,  The American Society for Cell Biology ,  The Japanese Society for AIDS Research ,  Japanese Society for Immunology ,  The Japanese Cancer Association ,  The Japanese Society of Hematology ,  European Hematology Association ,  International AIDS Society ,  The Japanese Society of HTLV-1 and Related Diseases ,  The Japan Society for Hematopoietic Cell Transplantation ,  The Japanese Association for Infectious Deaseases
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