YOKOSAKI YASUYUKI | Researcher Information

2018 - 2019 インテグリンα9β1低分子阻害剤の臨床医薬への展開
2017 - 2019 マウス肝線維化を抑制する新規インテグリン抗体の作用機序と治療応用への集大成研究
2017 - 2018 インテグリンα8β1阻害抗体の臨床医薬への展開
2015 - 2018 Role of polymeric OPN on fibrosis
2014 - 2016 A novel anti-integrin monoclonal antibody that attenuates mouse liver fibrosis: Mechanism of action and therapeutic application

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Akiko Sugiyama, Keishi Kanno, Norihisa Nishimichi, Shoichiro Ohta, Junya Ono, Simon J. Conway, Kenji Izuhara, Yasuyuki Yokosaki, Susumu Tazuma. Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via alpha(v) integrin interaction. JOURNAL OF GASTROENTEROLOGY. 2016. 51. 12. 1161-1174
Gina M. Many, Yasuyuki Yokosaki, Kitipong Uaesoontrachoon, Peter P. Nghiem, Luca Bello, Sherry Dadgar, Ying Yin, Jesse M. Damsker, Heather B. Cohen, Joe N. Kornegay, et al. OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory macrophages. EXPERIMENTAL PHYSIOLOGY. 2016. 101. 10. 1285-1300
Bridget Sackey-Aboagye, Abby L. Olsen, Sarmistha M. Mukherjee, Alexander Ventriglia, Yasuyuki Yokosaki, Linda E. Greenbaum, Gi Yun Lee, Hani Naga, Rebecca G. Wells. Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy. PLOS ONE. 2016. 11. 10. e0163737
Yoshiko Nakagawa, Tetsushi Sakuma, Norihisa Nishimichi, Yasuyuki Yokosaki, Noriyuki Yanaka, Toru Takeo, Naomi Nakagata, Takashi Yamamoto. Ultra-superovulation for the CRISPR-Cas9-mediated production of gene-knockout, single-amino-acid-substituted, and floxed mice. BIOLOGY OPEN. 2016. 5. 8. 1142-1148
Amin Khalifeh-Soltani, Arnold Ha, Michael J. Podolsky, Donald A. McCarthy, William McKleroy, Saeedeh Azary, Stephen Sakuma, Kevin M. Tharp, Nanyan Wu, Yasuyuki Yokosaki, et al. alpha 8 beta 1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism. ELIFE. 2016. 5. e13063

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Transglutaminases -Multiple Functional Modifiers and Targets for New Drug Discovery-
Springer 2016 ISBN:9784431558255
Health Risks From Exposure to Mineral Fibres: An International Perspective.
Captus University Publications 1993