Rchr
J-GLOBAL ID：200901058878590585
Update date: Aug. 27, 2020
Yasukawa Hideo
ヤスカワ ヒデオ | Yasukawa Hideo
Affiliation and department：
Kurume University The Cardiovascular Research Institute
About Kurume University The Cardiovascular Research Institute
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Detailed information
Homepage URL (1)：
http://www.med.kurume-u.ac.jp/med/imed3/index.html
Research field (1)：
Molecular biology
Research keywords (2)：
循環器内科学 分子生物学
, Molecular biology
Research theme for competitive and other funds (4)：
組織特異的な遺伝子発現制御法の開発と治療への応用
細胞内シグナル伝達制御と循環器疾患、炎症性循環器疾患の病態と治療
Signal transduction of Cytokine Receptors
Study on Cell Adhesion Molecules
MISC (25)：
SOCS3 is a physiological negative regulator for granulopoiesis and G-CSF receptor signaling (J Biol Chem). 2004
H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, K Takeda, S Akira, M Hoshijima, et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. NATURE IMMUNOLOGY. 2003. 4. 6. 551-556
The suppressors of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury (J Clin Invest). 2003
A Sasaki, K Inagaki-Ohara, T Yoshida, A Yamanaka, M Sasaki, H Yasukawa, AE Koromilas, A Yoshimura. The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6. JOURNAL OF BIOLOGICAL CHEMISTRY. 2003. 278. 4. 2432-2436
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy (Cell). 2002
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Books (2)：
STATs in cardiovascular system, Book title
2003
Molecular pathway for cardiac hypertrophy and heart failure progression, Book title
2003
Works (1)：
シグナル伝達制御因子SOCSの作用機構の解明、ウイルス性心筋炎におけるJAK/STAT/SOCS系の機能解析、炎症におけるマクロファージSOCS3の機能解析
Education (4)：
- 1996 Kurume University
- 1991 Kurume University Faculty of Medicine
Kurume University School of Medicine
Kurume University
Professional career (1)：
医学博士 (久留米大学)
Association Membership(s) (2)：
日本循環器学会
, 日本内科学会
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