Rchr
J-GLOBAL ID：200901058984667481   Update date: Feb. 04, 2024

Hashimoto Ari

ハシモト アリ | Hashimoto Ari
Affiliation and department：
Hokkaido University Graduate School of Medicine

About Hokkaido University Graduate School of Medicine


Research field  (2)： Medical biochemistry ,  Cell biology
Research keywords  (15)： Arf6 ,  AMAP1 ,  ArfGEF ,  乳癌 ,  癌浸潤 ,  血管新生 ,  細胞浸潤 ,  細胞内輸送 ,  ノックアウトマウス ,  endocytosis ,  細胞運動 ,  ArfGAP ,  AMAP2 ,  分子生物学 ,  Molecular Biology
Research theme for competitive and other funds  (15)：
  • 2022 - 2025 ARF6-AMAP1経路による細胞内動態変動と免疫回避作動の分子機序の解明
  • 2017 - 2022 Regulatory mechanisms of immune checkpoint PD-L1 via the Arf6 pathway in progressive cancer
  • 2011 - 2013 Elucidation of the molecular mechanisms of early breast cancer invasion and metastasis
  • 2009 - 2010 腫瘍血管における透過性亢進に関与する分子輸送のメカニズム及び病態の解明
  • 2008 - 2010 Analysis of common molecular mechanisms and pharmaceutical research in cancer invasion and angiogenesis
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Papers (51)：
  • Tsukasa Oikawa, Junya Hasegawa, Naomi Ohnishi, Yasuhito Onodera, Ari Hashimoto, Junko Sasaki, Takehiko Sasaki, Koji Ueda, Hisataka Sabe. p53 controls the nuclear entry and epigenetic modification of H3.1 by downregulating nuclear phosphatidic acid. 2023
  • Taiga Maemoto, Yuichi Kitai, Runa Takahashi, Haruka Shoji, Shunsuke Yamada, Shiho Takei, Daiki Ito, Ryuta Muromoto, Jun-Ichi Kashiwakura, Haruka Handa, et al. A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling. The Journal of biological chemistry. 2022. 299. 1. 102724-102724
  • Nabeel Kajihara, Takuto Kobayashi, Ryo Otsuka, Junko Nio-Kobayashi, Tomohiro Oshino, Masato Takahashi, Seiichi Imanishi, Ari Hashimoto, Haruka Wada, Ken-Ichiro Seino. Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer. Cancer immunology, immunotherapy : CII. 2022
  • Shigeru Hashimoto, Ari Hashimoto, Ryuta Muromoto, Yuichi Kitai, Kenji Oritani, Tadashi Matsuda. Central Roles of STAT3-Mediated Signals in Onset and Development of Cancers: Tumorigenesis and Immunosurveillance. Cells. 2022. 11. 16
  • Ari Hashimoto, Haruka Handa, Soichiro Hata, Shigeru Hashimoto. Orchestration of mesenchymal plasticity and immune evasiveness via rewiring of the metabolic program in pancreatic ductal adenocarcinoma. Frontiers in oncology. 2022. 12. 1005566-1005566
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MISC (88)：
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Professional career (2)：
  • Doctor of Philosophy (Kansai Medical University)
  • Master of Science (Kobe University)
Work history (3)：
  • 2009/10 - 現在 北海道大学 医学(系)研究科(研究院) 助教
  • 2002/04 - 2009/09 大阪バイオサイエンス研究所 研究員
  • 小野薬品工業 主任研究員
Association Membership(s) (4)：
JAPAN SOCIETY FOR CELL BIOLOGY ,  日本生化学会 ,  日本癌学会 ,  日本分子生物学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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