Rchr
J-GLOBAL ID:200901059206292779   Update date: Jan. 30, 2024

Oka Takashi

オカ タカシ | Oka Takashi
Affiliation and department:
Job title: Senior Assistant Professor
Homepage URL  (1): https://pxy-www.a.okayama-u.ac.jp/user/path/index.html
Research field  (5): Virology ,  Experimental pathology ,  Human pathology ,  Molecular biology ,  Biophysics
Research keywords  (10): Tumorigenesis and aberrant DNA methylation ,  Photo-Dynamic Therapy,(PDT) ,  HTLV-1 ,  エピジェネテイックス ,  白血病 ,  リンパ腫 ,  retrovirus ,  Epigenetics ,  Leukemia ,  Lymphoma
Research theme for competitive and other funds  (20):
  • 2016 - 2021 Single cell analysis of dynamic change of epigenetic abnormalities in adult T cell leukemia/lymphoma (ATL)
  • 2016 - 2019 Regulatory molecular mechanism of calcification on osteoblastic differentiation of human mesenchymal stem cells in vitro
  • 2014 - 2018 clarification of the mechanism of proteinuria related with tranport protein
  • 2014 - 2017 Identification of new biomarkers about Langerhans cell histiocytosis using mass spectrometry
  • 2013 - 2016 Epigenetic abnormalities during onset and progression of adult T-cell leukemia/lymphoma (ATL)
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Papers (122):
  • Yasuhisa Sando, Ken-Ichi Matsuoka, Yuichi Sumii, Takumi Kondo, Shuntaro Ikegawa, Hiroyuki Sugiura, Makoto Nakamura, Miki Iwamoto, Yusuke Meguri, Noboru Asada, et al. Author Correction: 5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy. Scientific reports. 2021. 11. 1. 6420-6420
  • Takashi Oka, Ken-ichi Matsuoka, Atae Utsunomiya. Sensitive Photodynamic Detection of Adult T-cell Leukemia/Lymphoma and Specific Leukemic Cell Death Induced by Photodynamic Therapy: Current Status in Hematopoietic Malignancies. Cancers. 2020. 12. 2. 335-335
  • Yasuhisa Sando, Ken-ichi Matsuoka, Yuichi Sumii, Takumi Kondo, Shuntaro Ikegawa, Hiroyuki Sugiura, Makoto Nakamura, Miki Iwamoto, Yusuke Meguri, Noboru Asada, et al. 5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy. Scientific Reports. 2020. 10. 1. 17237
  • Oka T, Mizuno H, Sakata M, Fujita H, Yoshino T, Yamano Y, Utsumi K, Masujima T, Utsunomiya A. Metabolic abnormalities in adult T-cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy. Scientific reports. 2018. 8. 1. 14979
  • Ichiro Murakami, Noriko Wada, Junko Nakashima, Mitsuko Iguchi, Makoto Toi, Yumiko Hashida, Tomonori Higuchi, Masanori Daibata, Michiko Matsushita, Takeshi Iwasaki, et al. Merkel cell polyomavirus and Langerhans cell neoplasm. Cell communication and signaling : CCS. 2018. 16. 1. 49-61
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MISC (53):
  • 佐藤 妃映, 岡 剛史, 神農 陽子, 鷲尾 佳奈, 村上 一郎, 大内田 守, 宇都宮 與, 吉野 正. 成人T細胞白血病/リンパ腫(ATL)を発症したHTLV-1キャリアにおける異常DNAメチル化の解析. 日本リンパ網内系学会会誌. 2017. 57. 88-88
  • 佐藤 妃映, 岡 剛史, 神農 陽子, 村上 一郎, 大内田 守, 宇都宮 與, 吉野 正. 成人T細胞白血病/リンパ腫(ATL)におけるDNA異常メチル化と病態の変動との関連. 日本病理学会会誌. 2017. 106. 1. 355-355
  • Kana Washio, Takashi Oka, Lamia Abdalkader, Michiko Muraoka, Akira Shimada, Megumi Oda, Hiaki Sato, Katsuyoshi Takata, Yoshitoyo Kagami, Norio Shimizu, et al. Gene expression analysis of hypersensitivity to mosquito bite, chronic active EBV infection and NK/T-lymphoma/leukemia. LEUKEMIA & LYMPHOMA. 2017. 58. 11. 2683-2694
  • 佐藤妃映, 岡剛史, 神農陽子, 鷲尾佳奈, 村上一郎, 大内田守, 宇都宮與, 吉野正. 成人T細胞白血病/リンパ腫(ATL)におけるDNA異常メチル化と予後との関連について. 日本HTLV-1学会学術集会. 2016. 3rd
  • 岡 剛史, 大内田 守, 岡田 康志, 山縣 一夫, 吉野 正. 成人T細胞白血病リンパ腫に於けるHTLV-1Tax遺伝子発現によるDNAメチル化の一細胞変動. 日本癌学会総会記事. 2015. 74回. E-1154
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Patents (12):
  • 異常活性化細胞検出による悪性腫瘍の検査方法及び異常活性化細胞除去還流返血治療装置
  • 高悪性型ATLLの診断のためのデータ取得方法、高悪性型ATLL診断用キットおよび高悪性型ATLL診断システム
  • 成人T細胞白血病・リンパ腫の予後推定法およびキット
  • 成人T細胞白血病・リンパ腫の予後推定法およびキット
  • 造血器腫瘍の検査方法及びキット
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Books (14):
  • 成人T細胞白血病・リンパ腫におけるエピジェネテイック異常と発症・進展機構の解析
    2014
  • Accumulation of Specific Epigenetic Abnormalities during Development and Progression of T cell Leukemia/Lymphoma.
    INTECH Open Access Publisher 2011
  • jointly worked
    2011
  • Gene silencing:New research
    Nova Science Publishers,Inc,New Yoek 2006
  • Immunoelectron microscopic study of the expression of T-cell receptor(TCR) /CD3 complex in human T-Cymphotropic Virus(HTLV) - producing cells (共著)
    in "Cells and Diseases" Hematolymphoreticular Study Group, Seoul, Korea 1997
more...
Lectures and oral presentations  (202):
  • HTLV-1キャリアにおける異常DNAメチル化と成人T細胞白血病/リンパ腫(ATL)発症との関連について
    (第4回日本HTLV-1学会学術集会 2017)
  • 成人T細胞白血病/リンパ腫(ATL)を発症したHTLV-1キャリアにおける異常DNAメチル化の解析
    (H29第57回日本リンパ網内系学会 2017)
  • 成人T細胞白血病/リンパ腫(ATL)におけるDNA異常メチル化と病態の変動との関連
    (第106回日本病理学会総会 2017)
  • Proteomic analysis on Langerhans cell histiocytosis patients and a new triple-risk factor model
    (第106回日本病理学会総会 2017)
  • Aberrant DNA methylation is associated with the clinical course in the same patients with ATL
    (The18th International Conference on Human Retrovirology: HTLV and Related Viruses HTLV 2017)
more...
Works (7):
  • 「中央西日本メディカルイノベーション2015」
    2015 -
  • 第33回「バイオシーズ公開会」NPO法人 近畿バイオインダストリー振興会議主催
    2015 -
  • 岡山大学知恵の見本市2012
    2012 -
  • Bio Japan 2011
    2011 -
  • Innovation JAPAN2004
    2004 -
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Education (1):
  • - 1983 Osaka University, Graduate School of Engineering Science, Dept of Biophysical Engineering
Professional career (2):
  • PhD.Ç (Osaka University)
  • Doctor of Medical Science (Kochi Medical School)
Work history (16):
  • 2019/04 - 現在 Academic Field of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Department of Hematology, Oncology and Respiratory Medicine, Senir Assistant Professor
  • 2019/04 - 現在 Academic Field of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Department of Hematology, Oncology and Respiratory Medicine, Senior Assistant Professor
  • 2017/04 - 2019/03 Academic Field of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Department of Virology Senior Assistant Professor
  • 2017 - 2019 - Senior Assistant Professor,Department of Virology,Social and Environmental Sciences,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
  • 2016 - 2017 岡山大学医歯薬学総合研究科病態制御科学専攻腫瘍病理学分野 講師
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Committee career (2):
  • 2015/04 - 2018/03 HTLV1学会 評議員
  • 2004 - 2017 日本病理学会 評議員
Awards (4):
  • 2012 - 日本白血病研究基金助成事業一般研究賞
  • 2006 - Best presentation Award,9th Korean-Japanese Lymphoretucular Workshop (KJLW 2006)
  • 2006 - Best presentation Award,9th Korean-Japanese Lymphoretucular Workshop (KJLW 2006)
  • 2003 - Award for an Outstanding Achievement,"8th World Congress on Advances in Oncology and 6th International Symposium on Molecular Medicine
Association Membership(s) (16):
日本免疫学会 ,  American Association for the Advancement of Science ,  日本分子生物学会 ,  国際微生物学会連合(International Union of Microbiological Societies) ,  エピジェネテイックス研究会 ,  アメリカ癌学会(American Association of Cancer Research) ,  国際比較白血病・関連疾患学会(International association for comparative research on leukemia and Related Disease) ,  国際HTLV学会(International Retrovirology Association) ,  日本病理学会 ,  日本ウイルス学会 ,  日本癌学会 ,  International union of microbiological societies ,  American Association of Cancer Research ,  International association for comparative research on leukemia and Related Diseases ,  (International Retrovirology Association ,  The Society of Japanese Virologists.
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