Akio Kanai

カナイアキオ | Akio Kanai

Affiliation and department：
Job title： Professor

Research field (3)： Evolutionary biology , Molecular biology , Genomics

Research keywords (6)： Genetic code, Molecular evolution , RNA processing, pre-tRNA-splicing, RNA ligase, Ribonuclease , Non-codingRNA, transfer RNA, ribosomal RNA, RNA-related enzymes , Systems biology, Synthetic biology, Genome biology , Archaea, Bacteria, RNA viruses , Non-codingRNA, transfer RNA, Archaea, RNA-related enzymes, Genetic code

Research theme for competitive and other funds (12)：

2019 - 2020 微生物生態系による原子炉内物体の腐食・変質に関する評価研究
2019 - 2020 専門書「冥王代生命学」の出版
2017 - 2020 多様性を有するRNAキナーゼの進化情報解析とその情報に基づいた酵素機能の改変
2014 - 2019 Hadean Bioscience
2014 - 2017 Studies on genome integrity of archaea in the extremophilic environments

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Papers (95)：

Tomoro Warashina, Asako Sato, Hiroshi Hinai, Nurislam Shaikhutdinov, Elena Shagimardanova, Hiroshi Mori, Satoshi Tamaki, Motofumi Saito, Yukihisa Sanada, Yoshito Sasaki, et al. Microbiome analysis of the restricted bacteria in radioactive element-containing water at the Fukushima Daiichi Nuclear Power Station. Applied and Environmental Microbiology. 2024. 90. 4. e0211323
Miu Naruki, Motofumi Saito, Masako Nomaguchi, Akio Kanai. Possible acquisition and molecular evolution ofvpugenes inferred from comprehensive sequence analysis of human and simian immunodeficiency viruses. 2024
Gota Kawai, Kiyoshi Okada, Seiki Baba, Asako Sato, Taiichi Sakamoto, Akio Kanai. Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus. The Journal of Biochemistry. 2024. in press
Motofumi Saito, Rerina Inose, Asako Sato, Masaru Tomita, Haruo Suzuki, Akio Kanai. Systematic Analysis of Diverse Polynucleotide Kinase Clp1 Family Proteins in Eukaryotes: Three Unique Clp1 Proteins of Trypanosoma brucei. Journal of Molecular Evolution. 2023. in press
Morita, T, Majdalani, N, Miura, M. C, Inose, R, Oshima, T, Tomita, M, Kanai, A, Gottesman, S. Identification of attenuators of transcriptional termination: implications for RNA regulation in Escherichia coli. mBio. 2022

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MISC (19)：

岡部晴子, 三浦昌浩, 佐藤朝子, 冨田勝, 冨田勝, 冨田勝, 足達俊吾, 金井昭夫, 金井昭夫, 金井昭夫. 超好熱性アーキアPyrococcus furiosusの熱ショック下における転写と翻訳の関係. 日本Archaea研究会講演会要旨集. 2022. 34th
Megumi TSURUMAKI, Motofumi SAITO, Shigenori MARUYAMA, Akio KANAI. Importance of Candidate Phyla Radiation (CPR) Bacteria for the Origin of Life. Journal of Geography (Chigaku Zasshi). 2020. 129. 6. 881-898
Takeyama, N, Takahashi, Y, Nagata, S, Sawaki, Y, Sato, T, Maruyama, S, Kanai, A. Importance of Prokaryotes for the Origin of Eukaryotes and the Global Environment at 2.4-2.0 Ga. Journal of Geography. 2020. 129. 6. 899-912
Hayashi Y, Otsuka K, Ebina M, Igarashi K, Takehara A, Matsumoto M, Kanai A, Igarashi K, Soga T, Matsui Y. Correction: Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (8289-8294) DOI: 10.1073/pnas.1620915114). Proceedings of the National Academy of Sciences of the United States of America. 2018. 115. 30
Kiyofumi Hamashima, Akio Kanai. Unexpected tRNAs that do not consistantly obey the universal genetic code. Seikagaku (in Japanese). 2014. 86. 4. 483-488

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Books (20)：

Hadean Bioscience
Asakura Publishing Co., Ltd. 2022 ISBN:4254171757
遺伝学の百科事典継承と多様性の源
丸善出版 2022 ISBN:9784621306604
Study of Corrosion and Degradation of the Objects in the Nuclear Reactor by Microorganisms, JAEA-Review 2021-048
Japan Atomic Energy Agency 2022
Current Advances in the Research of RNA Regulatory Enzymes
Frontiers Media SA 2019 ISBN:9782889632152
Genome Invading RNA Networks
Frontiers Media SA 2018 ISBN:9782889454778

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Lectures and oral presentations (83)：

PyrolysinはRtcB RNAリガーゼのC末端領域を特異的に切断し,tRNAエキソン断片の連結活性を抑制する
(日本RNA学会年会 2017)
配列類似性ネットワークに基づくHIV-1pol上のサブタイプ分化と対応する領域の解析
(日本生化学会大会 2017)
Pre-tRNAのスプライシングに関わるClp1タンパク質の大規模分子進化解析
(日本生化学会大会 2017)
配列類似性ネットワークを通じたHIV-1におけるアンチセンスタンパク質遺伝子の進化解析
(日本生化学会大会 2017)
バクテリアの有するグループIIイントロンの網羅的比較および進化解析
(日本生化学会大会 2017)

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Education (3)：

1987 - 1990 The University of Tokyo Graduate School of Pharmaceutical Sciences Life Science
1985 - 1987 Waseda University Graduate School of Science and Engineering Physics and Applied Physics
1981 - 1985 Waseda University Faculty of Education Biology

Professional career (1)：

Ph. D. (The University of Tokyo)

Work history (6)：

2022/04 - 現在 Professor, Systems Biology Program, Graduate School of Media and Governance, Keio University
2006/04 - 現在 Professor, Institute for Advanced Biosciences, Keio University
2001/04 - 2006/03 Associate Professor, Institute for Advanced Biosciences, Keio University
1996/04 - 2001/03 Group Leader, ERATO Project, Japan Science and Technology Agency (JST)
1992/11 - 1996/03 Researcher, Tokyo Metropolitan Institute of Medical Science, Japan

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Committee career (4)：

2020/05 - 現在 Visiting Professor, Yamaguchi University Graduate School of Medicine
2010/10 - 現在 Frontiers in Genetics (RNA), Editorial Board - Associate Editor
2010/06 - 2024/02 Frontiers in Microbiology (Virology), Editorial Board - Review Editor
2010/08 - 2023/04 PLOS ONE, Editorial Board - Academic Editor

Awards (1)：

2017/09 - 独立行政法人日本学術振興会「平成29年度『科研費』審査委員」表彰

Association Membership(s) (7)：

RNA Society of Japan (2021 Annual Meeting Organizer) , American Association for the Advancement of Science (AAAS) , RNA Society , Society of Evolutionary Studies, Japan , Japanese Biochemical Society (JBS) , Molecular Biology Society of Japan (MBSJ) , American Society for Microbiology (ASM)

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