Mima Takehiko

ミマタケヒコ | Mima Takehiko

Affiliation and department：
Job title： Professor

Research field (2)： Molecular biology , Bacteriology

Research keywords (8)： Burkholderia pseudomallei , Pseudomonas aeruginosa , small RNA , Vibrio , 発現調節 , Collagenase , 多剤耐性 , 多剤排出ポンプ

Research theme for competitive and other funds (16)：

2023 - 2026 細菌性コラゲナーゼのドメイン協働機構解明とその分子基盤に基づく組織新生因子の創出
2022 - 2025 Peptide LvによるOA疼痛制御機構の解明と疼痛治療シーズの創出
2021 - 2024 Development of ammoniated DLC coating for artificial vascular graft and evaluation of influence of ammoniation and cardboxylation on DLC coating
2021 - 2024 Integrated regulatory system by functional sRNA and mRNA-binging protein CsrA
2019 - 2023 Development of periodontal tissue regeneration therapy for horizontal alveolar bone resorption with collagen-binding FGF-2

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Papers (30)：

Asaduzzaman Md, 美間健彦, 後藤和義, 山本由弥子, 内山淳平, Sakon Joshua, 松下治. 細菌性コラゲナーゼの構造活性相関の解析(Structure-function analysis of Clostridial collagenases). 日本細菌学雑誌. 2023. 78. 1. 136-136
Asaduzzaman Md, 美間健彦, 後藤和義, 山本由弥子, 内山淳平, Sakon Joshua, 松下治. 細菌性コラゲナーゼの構造活性相関の解析(Structure-function analysis of Clostridial collagenases). 日本細菌学雑誌. 2023. 78. 1. 136-136
I. Putu Bayu Mayura, Kazuyoshi Gotoh, Hayato Nishimura, Erina Nakai, Takehiko Mima, Yumiko Yamamoto, Kenji Yokota, Osamu Matsushita. Elizabethkingia anophelis , an emerging pathogen, inhibits RAW 264.7 macrophage function. Microbiology and Immunology. 2021. 65. 8. 317-324
Shin Nakamura, Takashi Ito, Kentaro Okamoto, Takehiko Mima, Kentaro Uchida, Yasir D Siddiqui, Masahiro Ito, Masako Tai, Keisuke Okubo, Keisuke Yamashiro, et al. Acceleration of bone regeneration of horizontal bone defect in rats using collagen-binding basic fibroblast growth factor combined with collagen scaffolds. Journal of periodontology. 2019. 90. 9. 1043-1052
Chihiro Kageyama, Mayu Sato, Hiroyuki Sakae, Yuka Obayashi, Yoshiro Kawahara, Takehiko Mima, Osamu Matsushita, Kenji Yokota, Motowo Mizuno, Hiroyuki Okada. Increase in antibiotic resistant Helicobacter pylori in a University Hospital in Japan. Infection and drug resistance. 2019. 12. 597-602

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MISC (10)：

I Putu Bayu Mayura, Gotoh Kazuyoshi, 美間健彦, 山本由弥子, 横田憲治, 松下治, 萩谷英大. 敗血症性肺塞栓症患者から分離されたTsukamurella inchonensisの同定(Identification of Tsukamurella inchonensis isolated from septic pulmonary emboli(SPE) patient). 日本細菌学雑誌. 2021. 76. 1. 89-89
中村心, 伊東孝, 岡本憲太郎, 美間健彦, 内田健太郎, 山本直史, 松下治, 高柴正悟. コラーゲン結合型塩基性線維芽細胞増殖因子を用いた水平性骨吸収に対する歯周組織再生療法の開発. 日本歯科医学会誌. 2021. 40
松下治, 美間健彦, 後藤和義, 山本由弥子, Caviness Perry, Sakon Joshua, 内田健太郎, 中村心, 岡本健太郎, 高柴正悟. 細菌性コラゲナーゼのコラーゲン・アンカーの構造活性相関と歯周病治療への応用. 日本細菌学雑誌. 2020. 75. 1. 138-138
松下治, 美間健彦, 後藤和義, 山本由弥子, Perry Caviness, Sakon Joshua, 小出隆規, 内田健太郎, 中村心, 高柴正悟. 細菌性コラゲナーゼのコラーゲン・アンカーと歯周組織再生への応用(Collagen anchors of bacterial collagenases and their application to periodontal tissue regeneration). 日本細菌学雑誌. 2019. 74. 1. 84-84
岡本憲太郎, 中村心, 伊東孝, SIDDIQUI Yasir Dilshad, 美間健彦, 内田健太郎, 大森一弘, 山本直史, 松下治, 高柴正悟. コラーゲン結合型塩基性線維芽細胞成長因子はコラーゲン基剤からの徐放によって歯周組織再生を促進する. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2019. 150th

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Patents (7)：

神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット
Graft material for nerve regeneration, method for producing graft material for nerve regeneration, and kit for producing graft material for nerve regeneration
Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone
抗微生物活性を有するコラーゲン様ペプチド及びその組成物
Graft material for nerve regeneration, method for producing graft material for nerve regeneration, and kit for producing graft material for nerve regeneration

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Books (1)：

Pseudomonas : genomics and molecular biology
Caister Academic Press 2008 ISBN:9781904455196

Education (3)：

2002 - 2005 Okayama University The Graduate School of Natural Science and Technology
2000 - 2002 Okayama University The Graduate School of Natural Science and Technology
1996 - 2000 Okayama University Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

Ph.D. (Okayama University)

Work history (6)：

2021/02 - 現在 Ehime Prefectural University of Health Sciences Department of Medical Technology, Faculty of Health Sciences Professor
2012/04 - 2021/01 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences Assistant professor
2010/06 - 2012/03 Kitasato University School of Medicine
2007/01 - 2010/05 コロラド州立大学微生物学部リサーチサイエンティスト
2005/09 - 2006/12 コロラド州立大学微生物学部博士研究員

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Association Membership(s) (2)：

Japanese Society for Bacteriology , American Society for Microbiology

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