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J-GLOBAL ID：200901062593291379   Update date: Mar. 11, 2024

Ohkuchi Akihide

オオクチ アキヒデ | Ohkuchi Akihide
Affiliation and department：
Jichi Medical University

About Jichi Medical University


Job title： Professor
Research field  (4)： Obstetrics and gynecology ,  Other ,  Immunology ,  Molecular biology
Research keywords  (15)： placental growth factor (PlGF) ,  soluble fms-like tyrosine kinase 1 (sFlt-1) ,  uterine artery flow velocity waveform ,  blood pressure in pregnant women ,  inflammation ,  Fetal Membranes, Premature Rupture ,  Ureaplasma, Infection ,  neurodevelopmental impairments ,  bronchopulmonary dysplasia (BPD) ,  hypertensive disorders of pregnancy ,  preterm delivery, preterm birth ,  免疫学 ,  chorioamnionitis ,  clinical epidemiology ,  preeclampsia
Research theme for competitive and other funds  (17)：
  • 2023 - 2026 妊娠初期妊婦レジストリ事業の発足並びに早産期発症妊娠高血圧腎症予測モデルの開発
  • 2022 - 2025 胎盤由来エクソソームによる妊娠高血圧腎症の予知法に関する研究
  • 2021 - 2025 Methylation of genes related to cardiovascular and chronic kidney diseases in preterm low birth weight infants born to mothers with hypertensive disorders of pregnancy
  • 2020 - 2024 Elucidation of the novel function of trophoblast DROSHA as a novel therapeutic strategy for preventing congenital viral infection
  • 2020 - 2024 Protective effect of azithromycin (AZM) to the pregnant women with preterm premature rupture of the membranes (pPROM) occurring at <28 weeks of gestation on the development of bronchopulmonary dysplasia in the neonates (PPROM-AZM Study)
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Papers (231)：
  • Syunya Noguchi, Sadayuki Ohkura, Yasuyuki Negishi, Shohei Tozawa, Takami Takizawa, Rimpei Morita, Hironori Takahashi, Akihide Ohkuchi, Toshihiro Takizawa. Cytoplasmic and nuclear DROSHA in human villous trophoblasts. Journal of Reproductive Immunology. 2024. 162. 104189-104189
  • Syunya Noguchi, Shohei Tozawa, Takanobu Sakurai, Akihide Ohkuchi, Hironori Takahashi, Hiroyuki Fujiwara, Toshihiro Takizawa. BeWo exomeres are enriched for bioactive extracellular placenta-specific C19MC miRNAs. Journal of Reproductive Immunology. 2024. 161. 104187-104187
  • Yoshimitsu Wada, Hironori Takahashi, Manabu Ogoyama, Kenji Horie, Hirotada Suzuki, Rie Usui, Seung Chik Jwa, Akihide Ohkuchi, Hiroyuki Fujiwara. Uterine cervical conisation and chorioamnionitis: A nationwide observational study. BJOG : an international journal of obstetrics and gynaecology. 2023
  • Syunya Noguchi, Sadayuki Okura, Yasuyuki Negishi, Rimpei Morita, Akihide Ohkuchi, Hironori Takahashi, Toshihiro Takizawa. Localization of DROSHA in the trophoblast cell line BeWo infected with sindbis virus. Placenta. 2023. 141. 106-106
  • Toshihiro Takizawa, Syunya Noguchi, Sadayuki Okura, Yasuyuki Negishi, Rimpei Morita, Akihide Ohkuchi, Hironori Takahashi. Analysis of RNAs that bind to DROSHA expressed in the placental trophoblast. Placenta. 2023. 141. 100-100
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MISC (559)：
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Books (13)：
  • 臨床研究と論文作成のコツ 読む・研究する・書く
    東京医学社 2011 ISBN:488563203X
  • 1.周産期B.周産期疾患に対する処置と手術4.吸引分娩
    産婦人科診療指針(鈴木光明 編)中外医学社 東京 2005
  • 1.周産期B.周産期疾患に対する処置と手術1.子宮内容除去術と中期中絶
    産婦人科診療指針(鈴木光明 編)中外医学社 東京 2005
  • 1.周産期A.周産期疾患の診断・治療・管理16.妊娠高血圧症候群
    産婦人科診療指針(鈴木光明 編)中外医学社 東京 2005
  • 1.周産期A.周産期疾患の診断・治療・管理15.多胎妊娠
    産婦人科診療指針(鈴木光明 編)中外医学社 東京 2005
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Education (2)：
  • 1981 - 1987 Jichi Medical University School of Medicine
  • - 1987 Jichi Medical University Faculty of Medicine
Professional career (1)：
  • PhD (Jichi Medical University)
Work history (4)：
  • 2015 - 現在 Jichi Medical University
  • 2007 - 2015 Jichi Medical University Department of Obstetrics and Gynecology Associate Professor
  • 2002 - 2007 - 自治医科大学産婦人科学教室 講師
  • 1998 - 2002 Jichi Medical University
Committee career (10)：
  • 2023/04 - 現在 Japan Society of Obstetrics and Gynecology Evaluation Committee Member for JSOG Clinical Guideline for Obstetrics 2026
  • 2021/11 - 現在 Japan Society of Obstetrics and Gynecology Associate Editor for Glossary of Obstetrics and Gynecology, The 5th edition
  • 2013 - 現在 関東連合産科婦人科学会 地域活性化委員会委員
  • 2006 - 現在 日本産科婦人科学会 Associate Editor for the Journal of Obstetrics and Gynaecology Research
  • 2021/10 - 2023/09 Japan Society of Study of Hypertension in Pregnancy (JSSHP) Committee Chairperson for Academic Committee
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Awards (4)：
  • 2020/10 - Hypertension Research Award Temporary hypertension and white coat hypertension in the first trimester as risk factors for preeclampsia.
  • 2012 - ISSHP Best poster award
  • 2012 - Jichi Medical University The most valuable paper award
  • 2010 - Jichi Medical University The most valuable paper award
Association Membership(s) (13)：
日本医師会 ,  日本血管生物医学 ,  日本糖尿病・妊娠学会 ,  JAPAN SOCIETY OF MATERNAL HEALTH ,  日本高血圧学会 ,  日本早産学会 ,  Japan Placenta Association ,  ISSHP ,  日本生殖免疫学会 ,  日本周産期・新生児学会 ,  日本妊娠高血圧学会 ,  日本産科婦人科学会 ,  International Society for the Study of Hypertension in Pregnancy
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