Research theme for competitive and other funds (9)：
2014 - 2019 Establishment of RNA neo-taxonomy based on ncRNA cellular localizations
2016 - 2018 Mechanisms to make important noncoding RNAs from dispensable coding RNAs
2013 - 2018 Sorting mechanism for RNA plymerase II transcripts
2008 - 2012 Regulation of Nucleo-cytoplasmic Distribution of RNAs
2002 - 2006 Diversity and control of RNA export
RNAプロセシング
生体高分子の核・細胞質間輸送
RNA Processing
Nucleocytoplasmic Transport of macromolecules
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Papers (80)：
Sayaka Dantsuji, Mutsuhito Ohno, Ichiro Taniguchi. The hnRNP C tetramer binds to CBC on mRNA and impedes PHAX recruitment for the classification of RNA polymerase II transcripts. Nucleic Acids Research. 2023
Mitsuhiro Machitani, Ichiro Taniguchi, Asako McCloskey, Tatsuya Suzuki, Mutsuhito Ohno. The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response. RNA (New York, N.Y.). 2020. 26. 11. 1716-1725
Mitsuhiro Machitani, Ichiro Taniguchi, Mutsuhito Ohno. ARS2 Regulates Nuclear Paraspeckle Formation through 3′-End Processing and Stability of NEAT1 Long Noncoding RNA. Molecular and Cellular Biology. 2019. 40. 4
A cellular mechanism that sorts RNA transcripts according to their lengths.
(The 10th International Symposium for the Inter-institutional Network (ISIIN) 2015)
RNAi-mediated depletion of hnRNP C revealed a novel surveillance mechanism of proper mRNP formation.
(RNA Sciences in Cell and Developmental Biology. 2013)
Inhibition of mRNA export through dispersion of nucleoporins.
(2013)
HnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export.
(2013)
