Shiizaki Kazuhiro

シイザキカズヒロ | Shiizaki Kazuhiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sites.google.com/toyo.jp/shiizaki

Research field (3)： Environmental effects of chemicals , Clinical pharmacy , Molecular biology

Research keywords (9)： cancer immune evasion , immune tolerance , Drug-metabolizing enzymes , Nuclear Receptor , 環境化学物質 , AhR , 変異原物質 , Carcinogenesis , 発がん

Research theme for competitive and other funds (3)：

2019 - 2022 Study on immune evasion mechanism of tumor by AhR and its ligands
2015 - 2018 Development of a method to identify single molecule adducts generated on genomic DNA
2011 - 2013 Investigation of AhR ligand for the new pharmacotherapy for prevention of colorectal cancer

Papers (28)：

Sayoko Ito-Harashima, Mami Matano, Kana Onishi, Tomofumi Nomura, Saki Nakajima, Shingo Ebata, Kazuhiro Shiizaki, Masanobu Kawanishi, Takashi Yagi. Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids. Genes and Environment. 2020. 42. 1. 20-20
Yukari Totsuka, Yuya Maesako, Hanako Ono, Momoko Nagai, Mamoru Kato, Min Gi, Hideki Wanibuchi, Shoji Fukushima, Kazuhiro Shiizaki, Hitoshi Nakagama. Comprehensive analysis of dna adducts (DNA adductome analysis) in the liver of rats treated with 1,4-dioxane. Proceedings of the Japan Academy Series B: Physical and Biological Sciences. 2020. 96. 5. 180-187
Kazuhiro Shiizaki. Postlabeling/PAGE Method for Detection of DNA Adducts. Methods in Molecular Biology. 2020. 2119. 213-226
Kazuhiro Shiizaki, Kenta Kido, Yasuhiro Mizuta. Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells. PLoS ONE. 2019. 14. 11. e0224613
Nozomi Akiba, Kazuhiro Shiizaki, Yoshitaka Matsushima, Osamu Endo, Kazuho Inaba, Yukari Totsuka. Influence of GSH S-transferase on the mutagenicity induced by dichloromethane and 1,2-dichloropropane. Mutagenesis. 2017. 32. 4. 455-462

ｍore...

MISC (1)：

Chu Wai-Ling, Shiizaki Kazuhiro, Kawanishi Masanobu, Yagi Takashi. P-027 Agonistic and Antagonistic Activities of various Chemicals in Reporter Yeasts Expressing Estrogen Receptors α and β(Poster Session) :. 2008. 37. 120-120

Patents (1)：

「形質転換酵母、それを用いた分析方法および分析キット」

Lectures and oral presentations (51)：

Abortion in AhR knockout mice and maternal-fetal immunity
(The 46th Annual Meeting of the Molecular Biology Society 2023)
Effects of the Common Herbicide Bromacil on AhR and Drug Metabolizing Enzymes
(The 52nd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS) 2023)
除草剤ブロマシルによるAhR活性化および薬物代謝酵素の誘導
(第二回環境化学物質3学会合同大会(2023年6月徳島) 2023)
Involvement of AhR in tumor immunity and cancer metastasis in a tumor-bearing carcinoma model.
(2022)
汎用除草剤ブロマシルの AhR リガンド様作用
(日本環境変異原ゲノム学会第50回大会 2021)

ｍore...

Education (2)：

2002 - 2006 University of Tsukuba Graduate School of Comprehensive Human Sciences
1983 - 1987 Saitama University Faculty of Science Regulation Biology

Professional career (1)：

Ph.D.

Work history (11)：

2024/04 - 現在 Toyo University Faculty of Life Sciences Department of Life Sciences Associate Professor
2020/04 - 2024/04 Toyo University Faculty of Life Sciences Department of Applied Biosciences
2015/04 - 2020/03 Toyo University Faculty of Life Sciences associate professor
2013/10 - 2015/03 独立行政法人国立がん研究センター
2010/10 - 2013/09 埼玉県立がんセンター臨床腫瘍研究所

Show all

Committee career (4)：

2018/01 - 現在 The Japanese Environmental Mutagen and Genome Society (JEMS) associate editor
2018/01 - 現在日本環境変異原ゲノム学会評議員
2016/04 - 現在さいたま市立大宮北高校SSH運営指導委員
2019/01 - 2022/12 The Japanese Environmental Mutagen and Genome Society (JEMS) Second Editorial Committee

Awards (1)：

2009 - (社)近畿化学協会第9回環境技術賞

Association Membership(s) (6)：

The Japanese Environmental Mutagen and Genome Society , 環境ホルモン学会 , THE JAPANESE CANCER ASSOCIATION , The Japanese Environmental Mutagen Society , 埼玉昆虫談話会 , 分子生物学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page