Nobuhisa Ikuo

ノブヒサイクオ | Nobuhisa Ikuo

Affiliation and department：
Other affiliations (2)：

Homepage URL (1)： http://www.tmd.ac.jp/mri/scr/english/index.html

Research field (4)： Nutrition and health science , Developmental biology , Cell biology , Molecular biology

Research keywords (1)： hematopoiesis

Research theme for competitive and other funds (14)：

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Papers (65)：

Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T,... Miyakawa T. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. 2024. 12. 89376
Melig G, Nobuhisa I, Saito K, Tsukahara R, Itabashi A, Kanai Y, Kanai-Azuma M, Osawa M, Oshima M, Iwama A, Taga T. A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo. 2023. 43. 1. 41
Aimaitijiang A, Tabu K, Wang W, Nobuhisa I, Taga T. Glioma cells remotely promote erythropoiesis as a self-expanding strategy of cancer stem cells. Genes Cells. 2022. 27. 1. 25-42
Anani M, Nobuhisa I, Taga T. Sry-related High Mobility Group Box 17 functions as a tumor suppressor by antagonizing the Wnt pathway. Journal of Cancer Prevention. 2020. 25. 4. 204-212
Takahashi S, Nobuhisa I, Saito K, Melig G, Itabashi A, Harada K, Osawa M, Endo AT, Iwama A, Taga T. Sox17-mediated expression of adherent molecules is required for the maintenance of undifferentiated hematopoietic cluster formation in midgestation mouse embryos. Differentiation. 2020. 115. 53-61

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Books (1)：

Lectures and oral presentations (136)：

Rasip1 is a novel Sox17 downstream target gene and cooperating factor for the maintenance of the hematopoietic cluster cells
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
Mechanism of the emergence and the maintenance of hematopoietic stem cells during embryonic stages
(The 96th Annual Meeting of the Japanese Biochemical Society 2023)
Rasip1 helps maintenance of hematopoietic activities of mouse embryonic intra-aortic hematopoietic clusters.
(The 44th Annual Meeting of the Japanese Society of Inflammation and Regeneration 2023)
Rasip1 gene functioning downstream of Sox17 maintains the hematopoietic cluster-forming cells in E10.5 mouse embryos.
(The 20th Stem Cell Symposium 2023)
Rasip1 is involved in the positive regulation of hematopoietic activity in E10.5 intra-aortic hematopoietic cluster cells
(The 45th Annual Meeting of the Molecular Biology Society of Japan 2022)

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Education (3)：

1995 - 1998 Kyushu University Graduate School, Division of Natural Science Department of Chemistry
1993 - 1995 Kyushu University Graduate School, Division of Natural Science Department of Chemistry
1989 - 1993 Kyushu University Faculty of Science

Professional career (2)：

Work history (10)：

2022/04 - 福岡大学理学部
2021/09 - 2022/03 新潟大学理学部
2021/04 - 東京医科歯科大学難治疾患研究所
2021/04 - Nakamura Gakuen University Department of Nutritional Sciences Professor
2009/04 - 2021/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Systemic Organ Regulation Stem Cell Regulation Associate Professor

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Committee career (1)：

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