Rchr
J-GLOBAL ID:200901075276166717   Update date: Jan. 30, 2024

Sano Kuniaki

サノ クニアキ | Sano Kuniaki
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://nbgp.med.okayama-u.ac.jp/
Research field  (3): Cell biology ,  Molecular biology ,  Neuroscience - general
Research keywords  (2): 神経科学一般 ,  Neuro Science in General
Research theme for competitive and other funds  (8):
  • 2015 - 2019 Identification of RNA molecules that regulates expression of neural genes close to gene desert
  • 2011 - 2014 Roles of type II DNA topoisomerase in the interaction of distant genomic sites
  • 2009 - 2012 Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes
  • 2009 - 2010 SUMOylation is involved in the degradation of DNA topoisomerase IIβ induced by antitumor drug treatment
  • 2005 - 2007 DEVELOPMENT AND ITS PRACTICAL USE OF SCREENING METHODS ON HAZARD IDENTIFICATION USING CATALASE MUTANT GENE AS A PREDICTIVE INDEX
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Papers (4):
  • Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Norikazu Hara, Ryozo Kuwano, Jiyoung Kang, Masaru Tateno, Kimiko M. Tsutsui, Ken Tsutsui. Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening. Scientific Reports. 2020. 10. 1
  • Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Norikazu Hara, Ryozo Kuwano, Jiyoung Kang, Masaru Tateno, Kimiko M. Tsutsui, Ken Tsutsui. Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to modulate chromatin structure and gene expression. BioRXiV. 2018
  • Kawano S, Kato Y, Okada N, Sano K, Tsutsui K, Tsutsui KM, Ikeda S. DNA-binding activity of rat DNA topoisomerase II α C-terminal domain contributes to efficient DNA catenation in vitro. Journal of biochemistry. 2016. 159. 3. 363-369
  • Tsutsui K, Tsutsui KM, Miyaji M, Sano K. [Regulation of neuronal gene expression by DNA topoisomerase IIbeta]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009. 54. 11. 1333-1343
MISC (43):
Patents (4):
  • 負の超らせんDNA結合ドメイン
  • 負の超らせんDNA結合ドメイン
  • 負の超らせんDNA結合ドメイン
  • 負の超らせんDNA結合ドメイン
Books (3):
  • Catalase gene mutant mice; Acatalasemic and hypocatalasemic mice. In “Advances in Medicine and Biology”
    NOVA Science publishers 2013
  • 細胞核のダイナミクス
    シュプリンガー・フェアラーク東京,東京 2004
  • 廣川タンパク質化学 第4巻 酵素 4.5イソメラーゼ・リガーゼ
    廣川書店 2003
Lectures and oral presentations  (76):
  • 神経細胞終末分化過程でのDNAトポイソメラーゼIIβによるグローバルなクロマチン構造変換を介した遺伝子発現制御機構
    (第33回染色体ワークショップ・第14回核ダイナミクス研究会 2016)
  • DNAトポイソメラーゼIIαのC末端領域による酵素反応制御機構の解析
    (BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会) 2015)
  • DNAトポイソメラーゼIIβは遺伝子間領域に作用し遠隔ゲノム部位間の相互作用を媒介する
    (BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会) 2015)
  • Structural modeling of negatively-supercoiled DNA recognition peptide complexed with crossover DNA
    (BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会) 2015)
  • hnRNPU/SAF-A/SP120とDNAトポイソメラーゼIIβ複合体による神経細胞核のグローバルなクロマチン構造変換
    (BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会) 2015)
more...
Education (6):
  • - 1997 Okayama University
  • - 1997 Okayama University Graduate School, Division of National Science and Technology
  • - 1994 Okayama University
  • - 1994 Okayama University Graduate School, Division of Pharmaceutical Sciences
  • - 1992 Okayama University Faculty of Pharmaceutical Sciences Department of Pharmacy
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Professional career (3):
  • Bachelor of Pharmacy (Okayama University)
  • Doctor of Pharmacy (Okayama University)
  • Master of Pharmacy (Okayama University)
Work history (2):
  • 2004 - - 岡山大学医歯薬学総合研究科 助教
  • 2004 - - Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
Awards (1):
  • 2009 - 岡山医学会賞(新見賞)
Association Membership(s) (9):
日本生化学会 ,  日本神経科学会 ,  日本分子生物学会 ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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