Research theme for competitive and other funds (34)：
2022 - 2025 Fundamental study of the development of new therapy for the treatment of anticancer drug-induced persistent pain targeting glial cell activation
2020 - 2025 Impacts of sex differences for therapeutic hypothalamus orexinergic system to the link between chronic orofacial pain and sleep disorder
2017 - 2021 Neuroplastic changes in trigeminal nociceptive pathways following trigeminal nerve injury
2016 - 2020 Study of intractable pain in Sjogren's syndrome as a target for mechanically-gated ion channel Piezo2.
2017 - 2020 口腔乾燥に起因した病的口腔痛発症機構の総合的理解
2017 - 2020 三叉神経障害性疼痛に対する新たな予防および治療システムの構築
2015 - 2018 Functional recovery of injured inferior alveolar nerve using peripheral glial cell line-derived neurotrophic factor
2015 - 2018 A study of the impaired pain modulation system in the brain of BMS patients
2015 - 2018 Neural mechanism for developing therapy for masseter muscle pain triggered by myofascial pain in the neck shoulder
2014 - 2018 The effect of Cortical Spreading Depression on the autonomic nervous system
2015 - 2017 The involvement of microglia and early molecular signaling in the jaw face of abnormal pain onset
2013 - 2017 細胞移植による口腔感覚機能回復を目指した基礎研究の拠点形成
2013 - 2016 Involvement of medullary GABAergic system in extraterritorial neuropathic pain mechanisms associated with inferior alveolar nerve transection.
2013 - 2015 p38 phosphorylation and caspase1 in medullary microglia mediates ectopic orofacial inflammatory
2012 - 2015 Investigation of pathogenesis of burning mouth syndrome
2012 - 2015 Involvoment of satellite glial cells in trigeminal ganglion in tongue pain
2004 - 2006 A basic research on orofacial pain originating from cervical structure: Referred pain
2004 - 2006 Dysphagia Rehabilitation and Oral Health Care for Disabled Erderly.
2003 - 2004 Analysis of gene expression following maxillofacial inflammation in rat using complementary DNA microarray
2000 - 2001 REGULATION OF GENE EXPRESSION AND NEUROFUNCTION UNDER OROFACIAL PAIN
1999 - 2001 Effect of emotional state induced by expectation for pain on cortical neuronal activity in awake behaving monkeys
1999 - 2001 The basic study for the maintenance of oral health in an aging society
1999 - 2000 The mechanism of neuropatic pain model
1998 - 1998 歯根膜感覚に関する国際シンポジウムの企画
1997 - 1998 Effect of attentional shift on cortical nociceptive neuronal activity in monkeys
1991 - 1992 Research on the sensation perceived and intradental nerve activity following temperature changes in human teeth
1985 - 1987 Cortical Processing of Muscle Afferents in the Trigeminal System
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Papers (234)：
Kumi Soma, Suzuro Hitomi, Yoshinori Hayashi, Chihiro Soma, Jo Otsuji, Ikuko Shibuta, Akihiko Furukawa, Kentaro Urata, Ryoko Kurisu, Mamiko Yonemoto, et al. Neonatal Injury Modulates Incisional Pain Sensitivity in Adulthood: An Animal Study. Neuroscience. 2023. 519. 60-72
Nakaya Y, Iwata K, Kobayashi M. Insular cortical descending projections facilitate neuronal responses to noxious but not innoxious stimulation in rat trigeminal spinal subnucleus caudalis. Brain Res. 2023. 148248
Katagiri A, Tsubota K, Mikuzuki L, Nakamura S, Toyofuku A, Kato T, Bereiter DA, Iwata K. Tear secretion by Diquafosol suppresses the excitability of trigeminal brainstem nuclear complex neurons by reducing excessive P2Y2 expression in the trigeminal ganglion in dry eye rats. Neurosci Res. 2023. S0168-0102. 23. 3-12
Sayaka Asano, Akiko Okada-Ogawa, Momoyo Kobayashi, Mamiko Yonemoto, Yasushi Hojo, Ikuko Shibuta, Noboru Noma, Koichi Iwata, Suzuro Hitomi, Masamichi Shinoda. Involvement of interferon gamma signaling in spinal trigeminal caudal subnucleus astrocyte in orofacial neuropathic pain in rats with infraorbital nerve injury. Molecular pain. 2023. 19. 17448069231222403-17448069231222403
Katagiri A, Tsubota K, Mikuzuki L, Nakamura S, Toyofuku A, Kato T, Bereiter DA, Iwata K. Diquafosol sodium reduces neuronal activity in trigeminal subnucleus caudalis in a rat model of chronic dry eye disease. Neurosci Lett. 2023. 792. 136939
M. Maruno, M. Shinoda, K. Honda, R. Ito, K.Urata, Lee. J, N. Gionhaku and . K Iwata. P38 phosphorylation in trigeminal ganglion neurons contributes non-inflammatory tongue pain. J Orofacial Pain and Headache,. 2017. 31. 4. 372-380
TRPA1 contributes to capsaicin-induced facial cold hyperalgesia in rats.
(The 5th International Congress on Neuropathic Pain 2015)
Nitric oxide signaling contributes ectopic orofacial neuropathic pain.
(The 5th International Congress on Neuropathic Pain 2015)
Involvement of peripheral artemin signaling in tongue pain -Possible mechanism in burning mouth syndrome-.
(Overcoming barriers to the translation of pain research symposium 2015)
1979 - 1983 Nihon University Graduate School, Division of Dental Research Basic Dental Science
- 1979 Nihon University School of Dentistry Dental Science
Work history (5)：
2020/04 - 現在 Deapartment of Physiology Nihon University School of Dentistry Project Professor
2002/04 - 現在 日本大学歯学部 教授
1998/10 - 2002/03 大阪大学歯学部 助教授
1995/04 - 1998/09 日本大学歯学部 講師
1983/04 - 1995/03 日本大学歯学部 助手
Committee career (8)：
2014/09 - 現在 日本学術会議 連携会員
2008 - 現在 日本口腔顔面痛学会 副理事長
2006 - 現在 日本学術会議 連携会員
2009 - 2015 文部科学省 科学研究費委員会専門委員
日本疼痛学会 理事
歯科基礎医学会 評議員
日本生理学会 評議員
The Japanese Association for the Study of Pain Director
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Awards (1)：
1993 - 第5回 歯科基礎医学会賞
Association Membership(s) (7)：
日本疼痛学会
, 歯科基礎医学会
, 日本生理学会
, The Japanese Association for the Study of Pain
, Japanese Association for Oral Biology
, The Physiological Scienty of Japan
, 日本口腔顔面痛学会
