Rchr
J-GLOBAL ID:200901079946755579   Update date: Mar. 19, 2024

Kuzuyama Tomohisa

クズヤマ トモヒサ | Kuzuyama Tomohisa
Affiliation and department:
Homepage URL  (1): http://www.bt.a.u-tokyo.ac.jp/classes/cat2/labs-023/
Research field  (1): Bioorganic chemistry
Research keywords  (5): 生合成 ,  構造生物学 ,  合成生物学 ,  二次代謝産物 ,  放線菌
Research theme for competitive and other funds  (38):
  • 2022 - 2027 構造多様性一挙構築型生体反応の集積・予知・創出
  • 2022 - 2027 予知生合成科学・研究総括班
  • 2021 - 2024 生物合成系の再設計による革新的核酸系化合物の創製
  • 2021 - 2023 既存モチーフ配列を有さない革新的テルペン合成酵素の探索研究
  • 2016 - 2022 Redesigning Biosynthetic Machineries (International Activity Support Team)
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Papers (200):
  • Fan Zhao, Yoshitaka Moriwaki, Tomohiro Noguchi, Kentaro Shimizu, Tomohisa Kuzuyama, Tohru Terada. QM/MM Study of the Catalytic Mechanism and Substrate Specificity of the Aromatic Substrate C-Methyltransferase Fur6. Biochemistry. 2024
  • Genki Hibi, Taro Shiraishi, Tatsuki Umemura, Kenji Nemoto, Yusuke Ogura, Makoto Nishiyama, Tomohisa Kuzuyama. Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin. Nature Communications. 2023. 14. 1
  • Atsushi Minami, Kohei Nishi, Rikusui Yamada, Gai Jinnai, Hikari Shima, Sakiko Oishi, Hirofumi Akagawa, Toshihiro Aono, Makoto Hidaka, Haruhiko Masaki, et al. Relationship Between Domain and Function of the Yeast RNase T2, Rny1p, Which Mediates rRNA Degradation upon Starvation. 2023
  • Ryuhei Nagata, Makoto Nishiyama, Tomohisa Kuzuyama. Substrate Recognition Mechanism of a Trichostatin A-Forming Hydroxyamidotransferase. Biochemistry. 2023
  • Yuxun Zhu, Taro Shiraishi, Jianwen Lin, Keito Inaba, Atsuro Ito, Yusuke Ogura, Makoto Nishiyama, Tomohisa Kuzuyama. Complete Biosynthetic Pathway of the Phosphonate Phosphonothrixin: Two Distinct Thiamine Diphosphate-Dependent Enzymes Divide the Work to Form a C-C Bond. Journal of the American Chemical Society. 2022. 144. 37. 16715-16719
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MISC (78):
Education (4):
  • 1992 - 1995 The University of Tokyo Graduate School of Agricultural and Life Sciences Applied Biological Chemistry
  • 1990 - 1992 The University of Tokyo
  • 1988 - 1990 The University of Tokyo
  • 1986 - 1988 The University of Tokyo College of Arts and Sciences
Professional career (1):
  • 博士(農学) (東京大学)
Work history (5):
  • 2019/02 - 現在 The University of Tokyo Graduate School of Agricultural and Life Sciences
  • 2007/04 - 2019/01 The University of Tokyo Biotechnology Research Center
  • 2004/02 - 2007/03 The University of Tokyo Biotechnology Research Center
  • 2003/06 - 2004/01 Salk Institute for Biological Studies 文部科学省長期在外研究員
  • 1995/04 - 2004/01 The University of Tokyo Institute of Molecular and Cellular Biosciences
Awards (8):
  • 2016/10 - 日本感染症医薬品協会 住木・梅澤記念賞
  • 2015/09 - 日本放線菌学会賞
  • 2011/03 - 日本学士院学術奨励賞
  • 2011/02 - 日本学術振興会賞
  • 2006/04 - 文部科学大臣表彰若手科学者賞
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Association Membership(s) (2):
SOCIETY FOR ACTINOMYCETES JAPAN ,  JAPAN SOCIETY FOR BIOSCIENCE
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