2019 - 2024 Multimode autophagy: Diverse pathways and selectivity
2018 - 2021 Monitoring autophagy dynamics in vivo using innovative tools
2018 - 2020 p62によるオートファジーとストレス応答制御の統合的理解
2015 - 2018 International Activities Support for Autophagy Research
2015 - 2018 Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine
2015 - 2018 Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical application
2015 - 2018 Crosstalk between stress granules and autophagy in protein degradation
2015 - 2018 Morphofunctional analyses of autophagy for understanding the mechanism of the isolation membrane formation
2013 - 2018 Study on selective autophagy on cellular functions
2013 - 2018 Multidisciplinary research on autophagy: from molecular mechanisms to disease states
2014 - 2017 Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
2014 - 2017 Oxidative stress signaling as the molecular mechanism of chemo-resistance in esophageal cancer
2014 - 2017 Autophagy and metabolic regulation by multiple transcription factors
2014 - 2016 Physiological role of Ufm1 system
2013 - 2016 Does Spin1 mediate L-leucine-effects to ameliorate impaired autophagy?
2013 - 2016 Phosphorylation of p62/Sqstm1 activates Nrf2 during selective autophagy
2012 - 2015 Morphological and functional analyses of isolation membrane-associated tubules
2011 - 2014 Therapeutic strategy for the polyglutamine diseases by selective degradation of expanded polyglutamine proteins using polyglutamine-binding pepetides
2011 - 2013 The application of autophagy to prevent inner ear damage
2010 - 2012 Molecular mechanisms of p62 degradation in selective autophagy
2010 - 2012 Clarify the role of autophagy in influenza A virus infection andreplication
2009 - 2011 Bioimaging of mitochondrial dynamics and generation of model mice
2009 - 2010 オートファジーアクセサリー分子群の遺伝学的機能解析
2009 - 2010 オートファジーの破綻によるヒト病態発症機序の解明
2009 - 2010 Effects of mitophagy on cell death in Parkinson's disease model cells
2006 - 2010 Dynamics of autophagy and its physiological roles
2008 - 2009 封入体形成因子p62の代謝と病態発症
2008 - 2009 凝集体形成分子p62による神経変性疾患封入体形成機構
2006 - 2007 ユビキチン様分子による異常蛋白質代謝の解明
2006 - 2007 オートファジーによる選択的なユビキチン化蛋白質輸送機構の解明
2005 - 2005 ニューロンにおける品質管理の遺伝学的解析
2004 - 2005 ユビキチン様分子による異常蛋白質除去機構の解明
2001 - 2005 Studies on proteolysis mediated by the proteasomes and ubiquitin
Ryosuke Ishimura, Sota Ito, Gaoxin Mao, Satoko Komatsu-Hirota, Toshifumi Inada, Nobuo N. Noda, Masaaki Komatsu. Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control. Science Advances. 2023. 9. 33
Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu-Hirota, Ritsuko Arai, Elena Ryzhii, et al. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response. The EMBO journal. 2023. e113349
Reo Kurusu, Yuki Fujimoto, Hideaki Morishita, Daisuke Noshiro, Shuhei Takada, Koji Yamano, Hideaki Tanaka, Ritsuko Arai, Shun Kageyama, Tomoko Funakoshi, et al. Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex. Developmental cell. 2023
