TOUBAI Tomomi

• 2006 - 造血幹細胞移植時の移植片対宿主病(GVHD)の病態機序解析と効果的な移植片対腫瘍効果(GVT)の誘導法に関する研究
• 2006 - Immunobiology of graft-versus-host disease and immuno-reconstitution of after allogeneic stem cell transplantation

• Tomomi Toubai, Chelsea Malter, Isao Tawara, Chen Liu, Evelyn Nieves, Kathleen P. Lowler, Yaping Sun, Pavan Reddy. Immunization with host-type CD8 alpha(+) dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner. BLOOD. 2010. 115. 3. 724-735
• Tomomi Toubai, Chelsea Malter, Isao Tawara, Chen Liu, Evelyn Nieves, Kathleen P. Lowler, Yaping Sun, Pavan Reddy. Immunization with host-type CD8 alpha(+) dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner. BLOOD. 2010. 115. 3. 724-735
• Tomomi Toubai, Sophie Paczesny, Yusuke Shono, Junji Tanaka, Kathleen P. Lowler, Chelsea T. Malter, Masaharu Kasai, Masahiro Imamura. Mesenchymal Stem Cells for Treatment and Prevention of Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation. CURRENT STEM CELL RESEARCH & THERAPY. 2009. 4. 4. 252-259
• Tomomi Toubai, Sophie Paczesny, Yusuke Shono, Junji Tanaka, Kathleen P. Lowler, Chelsea T. Malter, Masaharu Kasai, Masahiro Imamura. Mesenchymal Stem Cells for Treatment and Prevention of Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation. CURRENT STEM CELL RESEARCH & THERAPY. 2009. 4. 4. 252-259
• Yaping Sun, Y. Eugene Chin, Elizabeth Weisiger, Chelsea Malter, Isao Tawara, Tomomi Toubai, Erin Gatza, Paolo Mascagni, Charles A. Dinarello, Pavan Reddy. Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3. JOURNAL OF IMMUNOLOGY. 2009. 182. 10. 5899-5903

ｍore...

• Crucial role for cross-presentation in the induction of GVHD by T cells directed against a single immunodominant minor histocompatibility antigen despite lack of epitope spreading
  (2010 BMT Tandem Meetings 2010)
• Crucial role for cross-presentation in the induction of GVHD by T cells directed against a single immunodominant minor histocompatibility antigen despite lack of epitope spreading
  (2010 BMT Tandem Meetings 2010)
• Novel vaccination strategy to reduce alloantigen specific responses
  (2009 BMT Tandem Meetings 2009)
• Ikaros deficiency enhances Notch signaling in host antigen presenting cells and differentially regulates Gvhd and GVL responses after experimental BMT
  (51th Annual Meeting of American Society of Hematology (ASH) 2009)
• Novel vaccination strategy to reduce alloantigen specific responses
  (2009 BMT Tandem Meetings 2009)

ｍore...

• - 2006 Hokkaido University Graduate School of Medicine
• - 1999 Yamagata University

• 医学博士

• 日本血液学会代議員

• 2010 - Travel grant: 2010 BMT Tandem Meetings, 2010. 2.24-28, Orlando, FL, USA.
• 2010 - Travel grant: 2010 BMT Tandem Meetings, 2010. 2.24-28, Orlando, FL, USA.
• 2008 - Young Investigator Awards (Second place). Southern Society for Clinical Investigation, 2008.2.21-23. New Orleans, Louisiana, USA.
• 2008 - Young Investigator Awards (Second place). Southern Society for Clinical Investigation, 2008.2.21-23. New Orleans, Louisiana, USA.
• 2007 - European Commission Marie Curie Actions scholarship: ESH Euroconference on translational research in transplantation, 2007.11.23-25, Leiden, Netherland.
2007 - European Commission Marie Curie Actions scholarship: ESH Euroconference on translational research in transplantation, 2007.11.23-25, Leiden, Netherland.
2006 - Travel grant :11th congress of the Eurpean Hematology Association (EHA), 2006. 6. 15-6.18. Amsterdam, Netherlands.
2006 - 平成18年度上原記念生命科学財団ポストドクトラルフェローシップ
2006 - Travel grant :11th congress of the Eurpean Hematology Association (EHA), 2006. 6. 15-6.18. Amsterdam, Netherlands.

American soceity of blood and marrow transplantation ,  European society of Hematology ,  American society of Hematology ,  日本化学療法学会 ,  日本輸血・細胞治療学会 ,  日本感染症学会 ,  日本造血細胞移植学会 ,  日本血液学会 ,  日本内科学会 ,  American soceity of blood and marrow transplantation ,  European society of Hematology ,  American society of Hematology