Shin Yongchol

シンヨンチョル | Shin Yongchol

Affiliation and department：
Job title： Associate Professor

Research field (1)： Molecular biology

Research theme for competitive and other funds (2)：

2011 - 2013 Development of cell culture methods using sea cucumber collagen fibrils
2009 - 2011 Development of artificial blood vessels using type IV collagen aggregates

Papers (21)：

Masayoshi Sakaguchi, Yudai Matsushima, Yusuke Nagamine, Tomoki Matsuhashi, Shotaro Honda, Shoi Okuda, Misa Ohno, Yasusato Sugahara, Yongchol Shin, Fumitaka Oyama, et al. Functional dissection of the N-terminal sequence of Clostridium sp G0005 glucoamylase: identification of components critical for folding the catalytic domain and for constructing the active site structure. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2017. 101. 6. 2415-2425
K. M. Wannemacher, H. Jiang, P. R. Hess, Y. Shin, K. Suzuki-Inoue, L. F. Brass. An expanded role for semaphorin 4D in platelets includes contact-dependent amplification of Clec-2 signaling. Journal of Thrombosis and Haemostasis. 2013. 11. 12. 2190-2193
Yongchol Shin, Masashi Akiyama, Koichi Kokame, Kenji Soejima, Toshiyuki Miyata. Binding of von Willebrand factor cleaving protease ADAMTS13 to Lys-plasmin(ogen). JOURNAL OF BIOCHEMISTRY. 2012. 152. 3. 251-258
Katsue Suzuki-Inoue, Osamu Inoue, Guo Ding, Satoshi Nishimura, Kazuya Hokamura, Koji Eto, Hirokazu Kashiwagi, Yoshiaki Tomiyama, Yutaka Yatomi, Kazuo Umemura, et al. Essential in Vivo Roles of the C-type Lectin Receptor CLEC-2 EMBRYONIC/NEONATAL LETHALITY OF CLEC-2-DEFICIENT MICE BY BLOOD/LYMPHATIC MISCONNECTIONS AND IMPAIRED THROMBUS FORMATION OF CLEC-2-DEFICIENT PLATELETS. JOURNAL OF BIOLOGICAL CHEMISTRY. 2010. 285. 32. 24494-24507
Tong Yin, Satoshi Takeshita, Yukiko Sato, Toshiyuki Sakata, Yongchol Shin, Shigenori Honda, Tomio Kawasaki, Hajime Tsuji, Tetsuhito Kojima, Seiji Madoiwa, et al. A large deletion of the PROSI gene in a deep vein thrombosis patient with protein S deficiency. THROMBOSIS AND HAEMOSTASIS. 2007. 98. 4. 783-789

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MISC (9)：

D Peiffer, YC Shin, A von Bubnoff, P Tran, M Mochii, A Kitayama, N Ueno, KWY Cho. DNA microarray optimizations: Increasing spot accuracy and automated identification of true microarray signals using Xenopus laevis as a model system. DEVELOPMENTAL BIOLOGY. 2002. 247. 2. 465-465
Y Shin, Okuyama, I, J Hasegawa, T Morita. Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation. THROMBOSIS RESEARCH. 2000. 99. 3. 239-247
D Yamada, Y Shin, T Morita. Nucleotide sequence of a cDNA encoding a common precursor of disintegrin flavostatin and hemorrhagic factor HR2a from the venom of Trimeresurus flavoviridis. FEBS LETTERS. 1999. 451. 3. 299-302
K Inoue, Y Ozaki, K Satoh, Y Wu, Y Yatomi, Y Shin, T Morita. Signal transduction pathways mediated by glycoprotein Ia/IIa in human platelets: Comparison with those of glycoprotein VI. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999. 256. 1. 114-120
Yongchol Shin, Takashi Morita. Rhodocytin, a functional novel platelet agonist belonging to the heterodimeric C-type lectin family, induces platelet aggregation independently of glycoprotein Ib. Biochemical and Biophysical Research Communications. 1998. 245. 3. 741-745

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Lectures and oral presentations (80)：

ヒト血漿へのストレプトキナーゼ添加によって活性化したplasminは,ヒト血漿中ADAMTS13を切断する
(第35回日本血栓止血学会学術集会 2013)
Sea cucumber collagen fibrils as cell culture substrates
(9th Pan Pacific Connective Tissue Societies Symposium 2013)
Type I collagen produced by cells in ascorbate depletion shows a lower denaturation temperature
(9th Pan Pacific Connective Tissue Societies Symposium 2013)
細胞外基質への細胞接着を特異的に阻害するヒメハブ粗毒由来タンパク質の探索
(第36回日本分子生物学会年会 2013)
Sea cucumber collagen fibrils as cell culture substrates
(9th Pan Pacific Connective Tissue Societies Symposium 2013)

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Professional career (3)：

工学士 (岡山大学)
修士(工学) (岡山大学)
博士(工学) (岡山大学)

Work history (4)：

2005 - 2008 国立循環器病センター研究所研究員
2000 - 2005 カリフォルニア大学アーバイン校研究員
2000 - 2000 Ministry of Agriculture, Forestry and Fisheries
1996 - 2000 Meiji Pharmaceutical University

Awards (3)：

2013 - 第35回日本血栓止血学会学術集会優秀ポスタ-賞
2008 - 平成十九年度国立循環器病センター研究所セミナー奨励賞
2007 - 第5回血液・血管オルビス Young Investigator Award 最優秀賞

Association Membership(s) (6)：

日本生化学会 , 日本分子生物学会 , 日本血栓止血学会 , The Japanese Biochemical Society , The Molecular Biology Society of Japan , The Japanese Society of Thrombosis and Hemostasis

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