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J-GLOBAL ID:200901080671475544   Update date: Mar. 26, 2024

Shibayama Naoya

シバヤマ ナオヤ | Shibayama Naoya
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.jichi.ac.jp/divbio/index.html
Research field  (2): Biophysics ,  Structural biochemistry
Research keywords  (8): ヘモグロビン ,  Hemoglobin ,  アロステリー ,  Allostery ,  X-ray crystallography ,  ゾル・ゲル法 ,  Sol-gel ,  Protein folding
Research theme for competitive and other funds  (17):
  • 2020 - 2023 Determination of single hemoglobin dynamics with x-rays
  • 2019 - 2023 ヘモグロビン結晶構造の半網羅的機能決定
  • 2016 - 2019 働く最中のヘモグロビン分子内動態の原子レベル追跡
  • 2014 - 2019 バイオロジーにおける3D活性サイト科学
  • 2015 - 2017 ヘモグロビンの四次構造変化を許容する結晶を用いた時分割構造解析法の開拓
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Papers (69):
  • Artoni Kevin R Ang, Yasufumi Umena, Ayana Sato-Tomita, Naoya Shibayama, Naohisa Happo, Riho Marumi, Yuta Yamamoto, Koji Kimura, Naomi Kawamura, Yu Takano, et al. Development of serial X-ray fluorescence holography for radiation-sensitive protein crystals. Journal of synchrotron radiation. 2023. 30. Pt 2. 368-378
  • Nagatomo, S, Shoji, M, Terada, T, Nakatani, K, Shigeta, Y, Hirota, S, Yanagisawa, S, Kubo, M, Kitagawa, T, Nagai, M, et al. Heme-bound tyrosine vibrations in hemoglobin M: resonance Raman, crystallography and DFT calculation. Biophys. J. 2022. 121. 14. 2767-2780
  • Naoki Yamamoto, Jiro Kikuchi, Yusuke Furukawa, Naoya Shibayama. Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system. PLOS ONE. 2022. 17. 5. e0261699-e0261699
  • Naoki Yamamoto, Maiko Kofu, Kenji Nakajima, Hiroshi Nakagawa, Naoya Shibayama. Freezable and Unfreezable Hydration Water: Distinct Contributions to Protein Dynamics Revealed by Neutron Scattering. The Journal of Physical Chemistry Letters. 2021. 12. xxxx. 2172-2176
  • Naoya Shibayama, Ayana Sato-Tomita, Mio Ohki, Kouhei Ichiyanagi, Sam-Yong Park. Direct observation of ligand migration within human hemoglobin at work. Proceedings of the National Academy of Sciences. 2020. 117. 9. 4741-4748
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MISC (31):
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Lectures and oral presentations  (43):
  • Slow Ligand Migration Dynamics in Tetramerio Hemoglobin at Cryogenic Temperature
    (物構研サイエンスフェスタ要旨集 2013)
  • セルフタイマーを内蔵するタンパク質EA4
    (日本蛋白質科学会年会プログラム・要旨集 2012)
  • 3SA4-05 The true nature of the allosteric equilibrium of hemoglobin(3SA4 Hemoglobin revisited,The 47th Annual Meeting of the Biophysical Society of Japan)
    (Biophysics 2009)
  • Vibrio parahaemolyticus由来機能未知c<sub>4</sub>-type cytochromeの大腸菌での大量発現,精製と物理化学的性質の決定
    (日本農芸化学会大会講演要旨集 2009)
  • パルス中性子源を用いたヒト由来デオキシヘモグロビンの中性子実験
    (京都大学原子炉実験所学術講演会報文集 2008)
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Education (4):
  • - 1985 Osaka University
  • - 1985 Osaka University Graduate School, Division of Engineering Science
  • - 1983 Osaka University School of Engineering Science Direct Affiliates
  • - 1983 Osaka University Faculty of Engineering Science
Professional career (1):
  • (BLANK)
Work history (1):
  • Jichi Medical University Lecturer
Committee career (1):
  • 2010/01 - 現在 日本生物物理学会 分野別専門委員(アロステリズム)
Association Membership(s) (3):
American Society of Biochemistry and Molecular Biology ,  日本生化学会 ,  日本生物物理学会
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