Rchr
J-GLOBAL ID:200901081018438656
Update date: Apr. 18, 2024
Hashimoto Hisashi
ハシモト ヒサシ | Hashimoto Hisashi
Affiliation and department:
Job title:
Professor
Research field (3):
Anatomy
, Developmental biology
, Cell biology
Research keywords (7):
Vascular system in the colonic mucosa
, 形態形成
, 三次元再構築
, 血管系
, morphogenesis
, three dimensional reconstruction
, Vascular system
Research theme for competitive and other funds (22):
- 2015 - 2018 Engineering bio-enamel in vitro using pluripotent stem cells and a novel organ culture system
- 2010 - 2014 Pathological and molecular biological investigations of congenital ataxia mouse bearing abnormal iron metabolism
- 2008 - 2010 Novel methods of regeneration of tooth using bone marrow cells-aim at order medical treatment-
- 2007 - 2008 Distribution of intravascular transplanted bone marrow derived mesenchymal stem cells and their derivatives
- 2007 - 2008 卵巣癌のシスプラチン耐性回避のためのシスプラチン・テネイシン抗体併用療法の研究
- 2006 - 2007 Study of the anti-cancer treatment that controls the interactions between breast cancer and its micro-environment for inhibition of invasion and metastasis.
- 2004 - 2007 Establishment of an hepatocyte cell line derived from human amnio-blast cells and the evaluation of its functions when transplanted and orientation to artificial bio-liver apparatus.
- 2005 - 2006 新世代の不妊治療法の開発,酸素電極による卵子・受精卵活性測定法を用いた
- 2004 - 2006 Novel methods for the induction on the differentiation of human amniotic stem cell to the pancreatic islet cells.
- 2002 - 2004 Identification of the genes involved in the cell differentiation of the pancreas β cell and pre-clinical study of the diabetes model animal.
- 2000 - 2003 Organogenesis of established ES cells and its application for clinical medicine.
- 1999 - 2000 Study on the pathogenetic mechanism of IgA nephropathy-like changes in the nivalenol (NIV) model
- 1997 - 1999 Development of the instrument for measuring respiration of cancer cells with oxygen electrode as a metablic indicator for anticancer drug screening
- 1997 - 1998 The role of vascular nets in intestinal villi formation.
- 1998 - 大腸の組織構築に関する研究
- 1998 - Study on histoarchitecture of large intestine
- 1996 - 1996 小腸絨毛におけるテネイシン(TN)の役割 -TNノックアウトマウスを用いた解析
- 1995 - 共焦点レーザー顕微鏡による血管網の三次元的解析
- 1995 - Three dimensional investigation of vascular nets by confocal laser scanning microscopy
- 1992 - 小腸絨毛の形成に関する研究
- 1992 - Study on the development of intestinal villi
- 1989 - 1989 プロラクチンレセプタ-発現機序の研究
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Papers (70):
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星野, 優, 西條, 広起, 辰巳, 徳史, 有廣, 誠二, 岡部, 正隆, 猿田, 雅之, 日下部, 守昭, 橋本, 尚詞, ホシノ, アツシ, サイジョウ, ヒロキ, et al. The Role of Tenascin C During the Development of DSS Induced Colitis (Original). Jikeikai medical journal. 2021. 68. 3. 67-79
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Tanaka K, Hashimoto H, Misawa T, Akiba T. The Prevention of Carboxymethylcellulose on Bowel Adhesions Induced by Talc Peritonitis in Mice. The Journal of surgical research. 2019. 234. 311-316
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Hisashi Hashimoto, Tomonori Kawabe, Takahiro Fukuda, Moriaki Kusakabe. A Novel Ataxic Mutant Mouse Line Having Sensory Neuropathy Shows Heavy Iron Deposition in Kidney. NEURODEGENERATIVE DISEASES. 2017. 17. 4-5. 181-198
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Atsushi Hoshino, Hisashi Hashimoto, Seiji Arihiro, Hiroshi Ozaki, Masayuki Saruta, Moriaki Kusakabe. Mesenchymal stem cells (MSCs) of BALB/cA have more protected effect against the inflammation of dextran sulfate sodium (DSS) induced colitis than those of C57BL. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 142-143
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Hiroki Saijo, Norifumi Tatsumi, Seiji Arihiro, Tomohiro Kato, Masataka Okabe, Hisao Tajiri, Hisashi Hashimoto. Microangiopathy triggers, and inducible nitric oxide synthase exacerbates dextran sulfate sodium-induced colitis. LABORATORY INVESTIGATION. 2015. 95. 7. 728-748
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MISC (206):
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西條広起, 岡部正隆, 橋本尚詞. 実験的大腸炎モデルマウスにおけるVascular endothelial growth factorの影響と粘膜障害との関連性. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2018. 123rd. 177
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星野 優, 橋本 尚詞, 有廣 誠二, 猿田 雅之, 日下部 守昭. BALB/cA由来の間葉系幹細胞(MSCs)は、C57BL由来MSCsよりもDSS誘発性腸炎モデルにおいて抗炎症効果を有する. 日本消化器病学会雑誌. 2017. 114. 臨増大会. A727-A727
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田中圭一朗, 橋本尚詞, 秋葉直志, 大木隆生. 胎便性腹膜炎モデルマウスの作製と癒着防止の検討. 日本外科学会定期学術集会(Web). 2017. 117th. ROMBUNNO.PS-037-8 (WEB ONLY)
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橋本 尚詞. 【次のステップへ弾みをつける! おさらい解剖生理】. クリニカルスタディ. 2015. 36. 3. 133-147
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星野優, 橋本尚詞, 有廣誠二, 日下部守昭. DSS腸炎モデルマウスに対する間葉系幹細胞投与による炎症抑制効果はTenascin-Cによって媒介される. 再生医療. 2015. 14. 201
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Books (17):
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解剖生理学 (新体系看護学全書 -人体の構造と機能)
メヂカルフレンド社 2017 ISBN:4839233179
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胸部/腹部・骨盤部
医学書院 2015 ISBN:9784260014113
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人体のしくみと働き (看護学入門)
メヂカルフレンド社 2013 ISBN:4839222363
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看護学入門 1巻 人体のしくみと働き 第3版
メヂカルフレンド社 2012 ISBN:4839222223
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パッと引けてしっかり使える人体解剖用語ポケット事典
成美堂出版 2011 ISBN:4415310141
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Education (4):
- 1981 - 1985 Kyoto University Graduate School of Medicine
- - 1985 Kyoto University Graduate School, Division of Medicine
- - 1981 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry
- - 1981 Tokyo Medical and Dental University Faculty of Dentistry
Professional career (1):
- Doctor of Medical Science (Kyoto University)
Work history (10):
- 2022/04 - 現在 Jikei University
- 2009/06 - 2022/03 The Jikei University School of Medicine Department of Anatomy Professor
- 2008/04 - 2009/05 Jikei University
- 1999/01 - 2008/03 Jikei University
- 1990 - 1998 Jikei University School of Medicine, Lecturer
- 1990 - 1998 Jikei University
- 1988 - 1990 Kyoto University, Lecturer
- 1988 - 1990 Kyoto University Faculty of Medicine
- 1986 - 1988 Kyoto University Faculty of Medicine
- 1986 - 1988 Kyoto University, Research Assistant
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Committee career (2):
- 2023 - 現在 医療系大学間共用試験実施評価機構 医学系CBT問題管理委員会 タイプA専門部会長
- 2019 - 2023 医療系大学間共用試験実施評価機構 医学系CBT問題評価・プール化小委員会 副委員長
Association Membership(s) (3):
American Society for Cell Biology
, American Association of Anatomists
, THE JAPANESE ASSOCIATION OF ANATOMISTS
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