Rchr
J-GLOBAL ID:200901081562370623   Update date: Feb. 01, 2024

Nakajima Hiroshi

ナカジマ ヒロシ | Nakajima Hiroshi
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.sci.osaka-cu.ac.jp/chem/biomol/
Research field  (5): Inorganic and coordination chemistry ,  Composite materials and interfaces ,  Functional solid-state chemistry ,  Molecular biochemistry ,  Biochemistry
Research keywords  (7): Metal Complex ,  Metal cluster ,  Protein engineering ,  Protein from thermophilic Bacterium ,  Sensor Protein ,  Engneering of Natural protein ,  Thermophilic bacteria
Research theme for competitive and other funds  (27):
  • 2020 - 2023 Development of Medicinal Molecules Releasing Mechanism Driven by Vibrationally Excited Prussian Blue by NIR light
  • 2019 - 2020 近赤外光に応答して一酸化炭素を放出する生体適合性分子の開発 -ガス医療への利用に向けてー
  • 2016 - 2017 医療への応用に向けた 生体適合性一酸化炭素放出ハイブリッド分子の開発
  • 2014 - 2016 光力学線療法への応用を志向する房状ポルフィリンカプセルの創出
  • 2014 - 2016 Creation of a protein-based nano-carrier that releases drug molecules depending on specific protease
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Papers (79):
  • Natsuo Nomura, Seiya Tanaka, Masakazu Hirotsu, Takanori Nishioka, Hiroshi Nakajima. Red-light responsive photoCORM activated in aqueous acid solution. Journal of Organometallic Chemistry. 2023. 984
  • Mingyue Jin, Sakiko Matsumoto, Takashi Ayaki, Hodaka Yamakado, Tomoyuki Taguchi, Natsuko Togawa, Ayumu Konno, Hirokazu Hirai, Hiroshi Nakajima, Shoji Komai, et al. DOPAnization of tyrosine in alpha-synuclein by tyrosine hydroxylase leads to the formation of oligomers. NATURE COMMUNICATIONS. 2022. 13. 1
  • Sheikh Muhammad Ibrahim, Sami Ben Aoun, Hiroshi Nakajima, Fethi Kooli, Yoshihito Watanabe. Radical Mediated Rapid In Vitro Formation of c-Type Cytochrome. BIOMOLECULES. 2022. 12. 10
  • Natsuki Yabune, Hiroshi Nakajima, Takanori Nishioka. Electronic and steric impact of bis-NHC ligands on reactions of Pt3S2 cores in trinuclear complexes bearing bis-NHC ligands with various lengths of alkylene bridges. Dalton Transactions. 2021. 50. 35. 12079-12082
  • Seiya Tanaka, Natsuo Nomura, Takanori Nishioka, Masakazu Hirotsu, Hiroshi Nakajima. Synthesis of iron(III)-carbonyl complex with variable wavelength range for CO release depending on protonation and deprotonation of axial phosphorous ligands. Journal of Organometallic Chemistry. 2021. 943. 121843-121843
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MISC (2):
  • Yuichi Tokita, Jusuke Shimura, Hiroshi Nakajima, Yoshio Goto, Yoshihito Watanabe. Mechanism of Intramolecular Electron Transfer in the Photoexcited Zn-Substituted Cytochrome c: Theoretical and Experimental Perspective (vol 130, pg 5302, 2008). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2011. 133. 1. 164-165
  • Nakajima H, Aono S, Shiro Y, Miyatake H, Park S. Ligand exchange on the heme in the transcriptional activator CooA regulated by CO. Biophysics. 1998. 38. 2. S36
Patents (1):
  • 一酸化炭素放出分子
Books (12):
  • 分子研レターズ86号_出身者の今
    分子科学研究所・分子研レターズ 2022
  • Creation of CO releasing complex sensitive to NIR light
    2019
  • Creation of CO releasing molecule triggered by NIR light irradiation
    2018
  • クライトン生物無機化学
    東京化学同人 2016
  • Protein and Enzyme Design, Vol 580, Methods in Enzymology
    Academic Press, UK 2016
more...
Lectures and oral presentations  (134):
  • Iron-based materials for releasing a physiologically active gas molecule in response to light within the phototherapeutic window
    (International Conference on Modern Trends in Inorganic Chemistry XIX 2022)
  • Iron(III)-based photoCORM responsive to light within the phototherapeutic window in acidic solution
    (2022)
  • Iron(III)-based CORM with dynamic variation in responsive wavelengths depending on H+
    (Asian Conference of Coordination Chemistry 2022)
  • 生体における金属イオンの役割 - 化学者の視点 -
    (宮水学園 2022)
  • フェリチンL134P変異体に内包されたプルシアンブルーの性状
    (第11回CSJ化学フェスタ 2021)
more...
Education (3):
  • 1993 - 1996 The Graduate University for Advanced Studies School of Physical Sciences Department of Structural Molecular Science
  • 1991 - 1993 Osaka University Graduate School of Engineering Division of Applied Chemistry
  • 1987 - 1991 Osaka University Faculty of Engineering Department of Applied Chemistry
Professional career (1):
  • Ph. D. (The Graduate University for Advanced Studies)
Work history (7):
  • 2015/04/01 - 現在 Osaka City University Graduate School of Science Molecular Materials Science Course Professor
  • 2015/04 - 現在 Osaka City University Graduate School of Science Professor
  • 2003/05 - 2015/03 Nagoya University Graduate School of Science Associate Professor
  • 2008/03 - ドイツミュンスター大学 化学科 非常勤講師
  • 2003/01 - 2003/04 Institute for Molecular Science
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Committee career (14):
  • 2019 - 2021 第72回錯体化学会討論会 実行委員長
  • 2017 - 2019 15th International Symposium on Applied Bioinorganic Chemistry Committee member
  • 2017 - 2019 第15回国際応用生物無機化学シンポジウム 国内実行委員
  • 2017/07/01 - 2018/06/30 第45回生体分子科学討論会 実行委員長
  • 2017/06 - 2018/06 生体分子科学討論会 第45回生体分子科学討論会実行委員
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Awards (1):
  • 2016 - 特別研究員等審査会専門委員(書面担当)表彰
Association Membership(s) (4):
The Biophysiocal Society of Japan ,  The Chemical Society of Japan ,  日本化学会 生体機能関連化学部会 ,  American Chemical Sciety
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