Rchr
J-GLOBAL ID:200901083072562098   Update date: Apr. 04, 2024

Aoyama Hiroshi

アオヤマ ヒロシ | Aoyama Hiroshi
Affiliation and department:
Job title: Professor
Research field  (1): Structural biochemistry
Research theme for competitive and other funds  (8):
  • 2021 - 2024 ホスト-ゲストを利用した二重鎖核酸のX線結晶構造解析
  • 2014 - 2017 Studies on molecular mechanism of paracellular pathway
  • 2011 - 2014 Chain Reaction of Drug Metabolism -A Comprehensive Study on the Cooperative and Competitive Drug Metabolism by CYP Isoforms
  • 2010 - 2012 Structural and functional analysis of GDE family proteins
  • 2008 - 2010 A Comprehensive Study on the Drug-Drug Interactions in Drug Metabolizing Enzyme CYP
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Papers (67):
  • Moeka Ishida, Rina Adachi, Kazuki Kobayashi, Yukiko Yamamoto, Chinatsu Kawahara, Tsuyoshi Yamada, Hiroshi Aoyama, Kyohei Kanomata, Shuji Akai, Patrick Y. S. Lam, et al. First atroposelective Chan-Lam coupling for the synthesis of C-N linked biaryls. Chemical Communications. 2024. 60. 678-681
  • Takao Yamaguchi, Naohiro Horie, Hiroshi Aoyama, Shinji Kumagai, Satoshi Obika. Mechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N′-methylguanidine-bridged nucleic acids. Nucleic Acids Research. 2023
  • Masaharu Takatsuki, Hiroshi Aoyama, Kenichi Murai, Mitsuhiro Arisawa, Makoto Sako. Heteroannulation of bicyclobutane derivatives via Au-catalyzed hydration to enol ethers and intramolecular cyclization giving spirocyclobutanes. Chemical Communications. 2023. 59. 48. 7467-7470
  • Yusuke Okanishi, Tohru Ishikawa, Takuya Jinnouchi, Satoshi Hayashi, Toshikatsu Takanami, Hiroshi Aoyama, Takehiko Yoshimitsu. Radical-Based Route to Functionalized Tetralin: Formal Total Synthesis of (±)-Hamigeran B. The Journal of Organic Chemistry. 2023. 88. 2. 1085-1092
  • Keigo Saito, Hiroshi Aoyama, Makoto Sako, Mitsuhiro Arisawa, Kenichi Murai. Double Ring Expansion Strategy for Fused 3-Benzazepines: Alternative Synthesis of the Dolby-Weinreb Enamine. The Journal of Organic Chemistry. 2022. 87. 24. 16947-16951
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MISC (83):
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Books (1):
  • 界面活性剤の選び方、使い方 事例集
    技術情報協会 2019 ISBN:9784861047534
Lectures and oral presentations  (13):
  • 3P018 X-ray structure of lipids in bovine heart Cytochrome c oxidase stabillized with 3-oxatridecyl-α-mannoside
    (Seibutsu Butsuri 2005)
  • 3P016 Improvement of resolution of cytochrome c oxidase crystal using annealing method
    (Seibutsu Butsuri 2005)
  • 3P113 Structural analysis of the x-ray induced photoreduction of cytochrome c oxidase
    (Seibutsu Butsuri 2005)
  • 3P110 Strategies for collecting high resolution data of bovine heart cytochrome c oxidase
    (Seibutsu Butsuri 2005)
  • 3P112 Analysis of the cyanide-bound structure of cytochrome c oxidase in the reduced state
    (Seibutsu Butsuri 2005)
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Work history (1):
  • 2024/04 - 現在 Juntendo University Faculty of Pharmacy Professor
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