2021 - 2024 Significance of Lamins as nuclear stiffness maintenance protein on ovarian cancer invasion and metstasis
2009 - 2011 Are tumor-infiltrating macrophages derived from monocyte-lineage belonging to the myeloid-derived suppressor cell?
2009 - 2011 Establishment of method to re-educate mecrophage differentiation towards dendritic cells on the view of regeneration medicine
2008 - 2010 The analysis of inflammatory cascade between antigen specific CTLs and liver injury using hepatitis model
2006 - 2008 Analysis of brain specific differentiation and maturation of tumor-infiltrating dendritic cells in glioma
2004 - 2006 Detection and regulation of hepatic diseases targeting TGF-β activation reaction.
2004 - 2005 Development of immunotherapy for glioma utilizing cell-free protein expression system
2002 - 2003 The development of immunotherapy for human brain tumor using molecular biothechnology
1997 - 1998 Human hepatoma antigen analyzed by genetic engineering method
1996 - 1996 遺伝子工学による腫瘍特異的キラーT細胞の効率的誘導法の確立
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Papers (113):
Miduki Ouchi, Sayaka Kobayashi, Yoshimi Nishijima, Naoki Inoue, Hayato Ikota, Akira Iwase, Hideaki Yokoo, Masanao Saio. Decreased lamin A and B1 expression results in nuclear enlargement in serous ovarian carcinoma, whereas lamin A-expressing tumor cells metastasize to lymph nodes. Pathology - Research and Practice. 2023. 154560-154560
Yui Mukade, Sayaka Kobayashi, Yoshimi Nishijima, Kiminori Kimura, Akira Watanabe, Hayato Ikota, Ken Shirabe, Hideaki Yokoo, Masanao Saio. Phosphotungstic Acid-treated Picrosirius Red Staining Improves Whole-slide Quantitative Analysis of Collagen in Histological Specimens. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2022. 221554221141140-221554221141140
Masamichi Kimura, Eiichi Ogawa, Kenichi Harada, Jun Imamura, Masanao Saio, Yoshihiro Ikura, Hiroshi Yatsuhashi, Kazumoto Murata, Kouichi Miura, Ichiro Ieiri, et al. Feasibility, safety and tolerability of the CREB-binding protein/β-catenin inhibitor OP-724 in patients with advanced primary biliary cholangitis: an investigator-initiated, open-label, non-randomised, two-centre, phase 1 study. BMJ open gastroenterology. 2022. 9. 1
Yoshimi Nishijima, Naoki Inoue, Akira Iwase, Hideaki Yokoo, Masanao Saio. MicroRNA 182, 183, 200a, and 200b exhibit strong correlations but no involvement in PTEN protein regulation in uterine endometrial carcinoma. Pathology, research and practice. 2022. 236. 153986-153986
Kiminori Kimura, Tatsuya Kanto, Shinji Shimoda, Kenichi Harada, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Eiichi Ogawa, Masanao Saio, Yoshihiro Ikura, et al. Safety, tolerability, and anti-fibrotic efficacy of the CBP/β-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study. eBioMedicine. 2022. 80. 104069-104069