Rchr
J-GLOBAL ID:200901084018503783
Update date: Feb. 01, 2024
Atsuo Sekiyama
セキヤマ アツオ | Atsuo Sekiyama
Affiliation and department:
Job title:
Professor
Research field (11):
Immunology
, Pathobiochemistry
, Clinical pharmacy
, Physiology
, Cell biology
, Molecular biology
, Clinical psychology
, Nano/micro-systems
, Nanomaterials
, Nutrition and health science
, Neuroscience - general
Research keywords (7):
プロテインアレー
, 引きこもり
, 自殺
, うつ病
, ストレス
, 心身相関
, 生体防御
Research theme for competitive and other funds (10):
- 2016 - 2019 Effect of stress on mitochondrial function and immune responses
- 2015 - 2018 Development of Technology for Therapeutic Effect Follow-up by Voice Pathophysiological Analyzing
- 2013 - 2016 Friction Between Institutional Change and Individual Cultural Orientation
- 2012 - 2015 Stress evaluation and mental screening using voice emotion recognition technology
- 2012 - 2015 The role of glucocorticoid in mitochondria-dependent resistance to anticancer therapy
- 2012 - 2015 The establishment of the objective indicator for the post-stroke depression
- 2008 - 2011 Total Control of Psycho-immune-endocrine system ; revealing stress specific cytokine cascade
- 2005 - 2009 Analysis of immune mechanisms of Alzheimer's disease and development of a novel treatment
- 2006 - 2007 Cytokines in stress response ; molecular basis as mediators for homeostasis
- ストレス、疲労などの外的要因によって疾患(主として精神疾患)が生じるメカニズムを分子レベルで明らかにし、障害の発生を回避もしくは抑制する。
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Papers (26):
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Koki Sakurai, Taichi Itou, Makiko Morita, Emiko Kasahara, Tetsuji Moriyama, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Atsuo Sekiyama, et al. Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice. PloS one. 2021. 16. 11. e0258364
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Nobuhiko Ebisutani, Hirokazu Fukui, Heihachiro Nishimura, Takashi Nakanishi, Kenki Morimoto, Shiho Itou, Ayumi Nakamura, Mizuki Masutani, Mika Hori, Toshihiko Tomita, et al. Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress. Frontiers in physiology. 2020. 11. 599582-599582
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Kiwamu Matsuoka, Fumihiko Yasuno, Akihiko Taguchi, Akihide Yamamoto, Katsufumi Kajimoto, Hiroaki Kazui, Takashi Kudo, Atsuo Sekiyama, Soichiro Kitamura, Kuniaki Kiuchi, et al. Delayed atrophy in posterior cingulate cortex and apathy after stroke. International journal of geriatric psychiatry. 2015. 30. 6. 566-72
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Emiko Kasahara, Atsuo Sekiyama, Mika Hori, Daisuke Kuratsune, Naoki Fujisawa, Dai Chida, Keiichi Hiramoto, Jiawei Li, Haruki Okamura, Masayasu Inoue, et al. Stress-Induced Glucocorticoid Release Upregulates Uncoupling Protein-2 Expression and Enhances Resistance to Endotoxin-Induced Lethality. Neuroimmunomodulation. 2015. 22. 5. 279-92
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Fumihiko Yasuno, Akihiko Taguchi, Akihide Yamamoto, Katsufumi Kajimoto, Hiroaki Kazui, Takashi Kudo, Akie Kikuchi-Taura, Atsuo Sekiyama, Toshifumi Kishimoto, Hidehiro Iida, et al. Microstructural abnormality in white matter, regulatory T lymphocytes, and depressive symptoms after stroke. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2014. 14. 4. 213-21
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MISC (40):
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森本 健揮, 笠原 恵美子, 伊藤 史穂, 竹中 美月, 村山 真人, 堀 美香, 関山 敦生. ストレスによるうつ形成のトランスレーショナル・バイオマーカーの検討. 生命科学系学会合同年次大会. 2017. 2017年度. [2AT26-1064)]
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笠原 恵美子, 堀 美香, 村山 真人, 竹中 美月, 関山 敦生. マクロファージの自然免疫応答におけるグルタミン酸の影響. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-0940]
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関山 敦生. 【IT技術とストレスチェック】健康とこころのモニタリング. 心と社会. 2016. 47. 3. 38-46
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細田 明美, 岡井 康二, 笠原 恵美子, 清水 雅富, 関山 敦生, 岡井 紀代香[東]. リポポリサッカライドによるマクロファージ培養細胞の一酸化窒素および炎症性サイトカイン産生に及ぼす日本産赤米・黒米・白玄米のぬか成分の免疫制御活性(Potent Modulating Activity of Red, Black and Brown Rice Bran on Nitric Oxide and Cytokine Production of Macrophages(RAW 264.7 Cells) induced by Lipopolysaccharide). 東京医療保健大学紀要. 2015. 10. 1. 1-7
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山本 彬, 鈴木 朋久, 高橋 正洋, 松尾 雅博, 森田 幸代, 関山 敦生, 山田 尚登. クロザピンによる薬原性発熱とサイトカインとの関連. 精神神経学雑誌. 2015. 117. 2. 160-160
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Patents (12):
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