Research theme for competitive and other funds (13):
2021 - 2026 Chemical Challenge for Elucidation of the Molecular Mechanism of Lipid Peroxidation-mediated Necrosis
2021 - 2024 炎症によるがん転移促進の核心を担う制御性単球の機能
2020 - 2023 Mechanisms of tissue repair by immnuoregulatory monocytes
2013 - 2016 Functional analysis of tumor-associated macrophages accumulating in dead tumor cells
2008 - 2009 死細胞処理による末梢性自己免疫寛容誘導機構の解明
2007 - 2009 Mechanisms of tolerance induction by apoptotic cell phagocytosis
2004 - 2005 Physiological roles of apoptotic cell clearance
2004 - 2004 自然免疫系による死細胞の貧食と自己に対する免疫寛容の維持機構
2000 - 2004 MOLECULAR MECHANISM OF CELL DEATH AND ITS PHYSIOLOGICAL ROLE
2003 - 2003 自然免疫系におけるアポトーシス細胞の貧食に伴う炎症調節機構の解明
2002 - 2003 Molecular Mechanisms of Apoptotic Cell Phagocytosis by Macrophages
2000 - 2001 Molecular mechanism for phagocytosis of apoptotic cells
1994 - 1999 アポト-シスの分子機構とその生理作用
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Papers (112):
Kenichi Asano, Kenta Kikuchi, Miki Takehara, Manami Ogasawara, Yuki Yoshioka, Kie Ohnishi, Ayaka Iwata, Shigeomi Shimizu, Masato Tanaka. Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity. Biochemical and Biophysical Research Communications. 2023. 684. 149135-149135
Abigail K. Grootveld, Wunna Kyaw, Veera Panova, Angelica W.Y. Lau, Emily Ashwin, Guillaume Seuzaret, Rama Dhenni, Nayan Deger Bhattacharyya, Weng Hua Khoo, Maté Biro, et al. Apoptotic cell fragments locally activate tingible body macrophages in the germinal center. Cell. 2023. 186. 6. 1144-1161.e18
Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, et al. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell reports. 2023. 42. 3. 112165-112165
Chihiro Kurematsu, Masato Sawada, Masaki Ohmuraya, Motoki Tanaka, Kazuya Kuboyama, Takashi Ogino, Mami Matsumoto, Hisashi Oishi, Hiroyuki Inada, Yuri Ishido, et al. Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine. The Journal of experimental medicine. 2022. 219. 4
Abdouramane Camara, Alice C Lavanant, Jun Abe, Henri Lee Desforges, Yannick O Alexandre, Erika Girardi, Zinaida Igamberdieva, Kenichi Asano, Masato Tanaka, Thomas Hehlgans, et al. CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 3
Philip E. Boulais, Nico van Rooijen, Masato Tanaka, Paul S. Frenette. F4/80 Identifies a Subset of Non-Mobilizable Bone Marrow HSCs Involved in Stress-Induced Hematopoiesis. BLOOD. 2016. 128. 22
Y. Ogawa, T. Suganami, M. Tanaka, M. Itoh. Parenchymal-stromal cell interaction in metabolic diseases. Inflamm. Regen. 2015. 35. 4. 167-171-171
Andrew Chow, Matthew Huggins, Jalal Ahmed, Daniel Lucas, Daigo Hashimoto, Yuya Kunisaki, Sandra Pinho, Marylene Leboeuef, Clara Noizat, Nico van Rooijen, et al. CD169(+) Macrophages Regulate Erythropoiesis Under Homeostasis, Recovery From Erythron Injury and in JAK2(V617F)-Induced Polycythemia Vera. BLOOD. 2012. 120. 21
2011/04 - 現在 Tokyo University of Pharmacy and Life Sciences Laboratory of Immune Regulation School of Life Sciences Professor
2002/08 - 2011/03 RIKEN Research Center Team Leader
2000/01 - 2004/03 Osaka University Medical School the Department of Genetics Assistant Professor
1999/08 - 1999/12 Osaka University Medical School The Department of Genetics Research Associate
1997/09 - 1999/07 Tularik Inc. postdoctoral fellow
1996/12 - 1997/08 Osaka University Medical School Department of Genetics Research Associate
1995/08 - 1996/11 日本学術振興会 特別研究員
1995/04 - 1995/07 大阪バイオサイエンス研究所 非常勤職員
1993/11 - 1995/03 大阪バイオサイエンス研究所 共同研究員
1989/06 - 1991/05 武蔵野赤十字病院 内科 医員
1988/06 - 1989/05 Tokyo Medical and Dental University University Hospital of Medicine
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Committee career (3):
2017/10 - 現在 マクロファージ分子細胞生物学研究会 幹事
2015/07 - 現在 日本CellDeath学会 理事
2014 - 現在 日本免疫学会 評議委員
Association Membership(s) (5):
The Japanese Society for Cell Death Research
, International Symposium on Molecular Cell Biology of Macrophages
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE JAPANESE BIOCHEMICAL SOCIETY