Tanaka Yosuke

タナカヨウスケ | Tanaka Yosuke

Affiliation and department：
Other affiliations (1)：

The University of Tokyo

Research field (7)： Internal medicine - General , Gastroenterology , Developmental biology , Metabolism and endocrinology , Cell biology , Anatomy , Neuroscience - general

Research keywords (12)： NASH/NAFLD , 左右軸決定 , 統合失調症 , 細胞外小胞 , 細胞内物質輸送 , 発生生物学 , 解剖学一般 , 神経科学 , 細胞生物学 , general anatomy , molecular biology , cell biology

Research theme for competitive and other funds (12)：

2023 - 2026 キネシンによってシャペロン蛋白の局在を整える新しい抗糖尿病戦略の開発
2022 - 2024 脂肪新生酵素群の包括的制御経路の強化による新規非アルコール性脂肪肝炎治療薬の探索
2022 - 2024 心筋梗塞後の早期回復に資するヒト間葉系幹細胞由来細胞外小胞の質的・量的分泌促進法の開発
2020 - 2024 Mouse molecular genetics of kinesin molecular motor preventing diabetes
2020 - 2021 キネシンモーターのかかわる非アルコール性肝障害の分子機構の解析

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Papers (49)：

Yosuke Tanaka, Ai Morozumi, Nobutaka Hirokawa. Nodal flow transfers polycystin to determine mouse left-right asymmetry. Developmental cell. 2023. 58. 16. 1447-1461
Yuansong Wan, Momo Morikawa, Manatsu Morikawa, Suguru Iwata, Muhammad Imran Naseer, Adeel Gulzar Ahmed Chaudhary, Yosuke Tanaka, Nobutaka Hirokawa. KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway. The Journal of cell biology. 2023. 222. 2
Shuo Wang, Yosuke Tanaka, Ying Xu, Sen Takeda, Nobutaka Hirokawa. KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice. Developmental cell. 2022. 57. 19. 2273-2289
Manatsu Morikawa, Nivedita U Jerath, Tadayuki Ogawa, Momo Morikawa, Yosuke Tanaka, Michael E Shy, Stephan Zuchner, Nobutaka Hirokawa. A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle. The EMBO Journal. 2022. 41. 5. e108899
Shogo Yoshihara, Xuguang Jiang, Momo Morikawa, Tadayuki Ogawa, Sotaro Ichinose, Hirooki Yabe, Akiyoshi Kakita, Manabu Toyoshima, Yasuto Kunii, Takeo Yoshikawa, et al. Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport. Cell reports. 2021. 35. 2. 108971-108971

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MISC (22)：

田中庸介. なぜ指は5本になるのか? 体の座標を決める仕組み. 生物物理. 2023. 63. 5. 266-269
田中庸介. 多指症を防ぐモルフォゲン濃度勾配の新しい形成機構. 生体の科学. 2023. 74. 4. 376-381
W. Yang, Y. Tanaka, M. Bundo, N. Hirokawa. Antioxidant signaling involving the microtubule motor KIF12 is an intracellular target of nutrition excess in beta cells. MOLECULAR BIOLOGY OF THE CELL. 2014. 25
Yasushi Okada, Sen Takeda, Yosuke Tanaka, Nobutaka Hirokawa. Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. CELL STRUCTURE AND FUNCTION. 2005. 30. 34-34
OJunlin Teng, Tatemitsu Rai, Yosuke Tanaka, Yosuke Takei, Takao Nakata, Motoyuki Hirasawa, Ashok B. Kulkarni, Nobutaka Hirokawa. The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. CELL STRUCTURE AND FUNCTION. 2005. 30. 67-67

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Patents (2)：

生理活性物質を含有する細胞外小胞を生産する方法
糖尿病の治療又は予防剤、糖尿病モデル非ヒト動物、糖尿病の治療又は予防剤のスクリーニング方法及びキット

Books (1)：

Encyclopedia of Cell Biology
Academic Press 2015 ISBN:0123944473

Education (2)：

1993 - 1996 The University of Tokyo Graduate School of Medicine
1989 - 1993 The University of Tokyo Faculty of Medicine School of Medicine

Professional career (1)：

(BLANK)

Work history (4)：

2023/04 - 現在 The University of Tokyo Art Center of The University of Tokyo
2017/05 - 現在東京大学大学院医学系研究科分子細胞生物学専攻
1996/05 - 2017/04 The University of Tokyo
1994/04 - 1996/04 Japan Society for the Promotion of Science

Association Membership(s) (5)：

International Society for Extracellular Vesicles (ISEV) , 日本神経科学学会 , 日本細胞生物学会 , American Society for Cell Biology , 日本解剖学会

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