Rchr
J-GLOBAL ID：200901084896818128   Update date: Jan. 30, 2024

Takahashi Masaharu

タカハシ マサハル | Takahashi Masaharu
Affiliation and department：
Jichi Medical University

About Jichi Medical University


Research field  (2)： Immunology ,  Virology
Research keywords  (2)： 肝炎ウイルス ,  Viral Hepatitis
Research theme for competitive and other funds  (11)：
  • 2013 - 2015 Research on mechanism of hepatitis E virus egress utilizing membrane traffic
  • 2011 - 2012 Studies on the identification and acquisition mechanism ofcell-derived membrane on the surface of hepatitis E virus particles
  • 2010 - 2012 Characterization of cell culture-generated hepatitis E virus particles:evaluation of neutralizing antibodies-inducing ability as the material of inactivated vaccineproduction
  • 2010 - 2012 Research on release mechanism, genome mutations and cellular receptor of hepatitis E virus (HEV) using cell culture systems for HEV
  • 2007 - 2008 Characterization of hepatitis E virus (HEV) particles and analysis of replication mechanism by using a cell culture system for HEV
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Papers (200)：
  • Shigeo Nagashima, Putu Prathiwi Primadharsini, Takashi Nishiyama, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform. JOURNAL OF VIROLOGY. 2023
  • Masaharu Takahashi, Satoshi Kunita, Tsutomu Nishizawa, Hiroshi Ohnishi, Putu Prathiwi Primadharsini, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto. Infection Dynamics and Genomic Mutations of Hepatitis E Virus in Naturally Infected Pigs on a Farrow-to-Finish Farm in Japan: A Survey from 2012 to 2021. VIRUSES-BASEL. 2023. 15. 7
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Toshinori Tanaka, Suljid Jirintai, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Development and Characterization of Efficient Cell Culture Systems for Genotype 1 Hepatitis E Virus and Its Infectious cDNA Clone. VIRUSES-BASEL. 2023. 15. 4
  • Satoshi Takakusagi, Hitoshi Takagi, Yuichi Yamazaki, Takashi Kosone, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Chronic hepatitis E in an elderly immunocompetent patient who achieved a sustained virologic response with ribavirin treatment. Clinical journal of gastroenterology. 2023. 16. 2. 206-215
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Masaharu Takahashi, Kazumoto Murata, Hiroaki Okamoto. Ritonavir Blocks Hepatitis E Virus Internalization and Clears Hepatitis E Virus In Vitro with Ribavirin. VIRUSES-BASEL. 2022. 14. 11
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MISC (19)：
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Education (4)：
  • - 1985 Iwate University Graduate School of Agriculture
  • - 1985 Iwate University Graduate School, Division of Agriculture
  • - 1983 Iwate University Faculty of Agriculture
  • - 1983 Iwate University Faculty of Agriculture
Professional career (2)：
  • (BLANK) (Iwate University)
  • 博士(医学) (自治医科大学(JMU))
Work history (7)：
  • 2000 - 2003 Jichi Medical University School of Medicine
  • 2000 - 2003 Reseach Associate, Jichi Medical School
  • 2003 - - 自治医科大学医学部 学内講師
  • 2003 - - Lecturer, Jichi Medical School
  • 1985 - 1999 (株)特殊免疫研究所 研究員
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