Rchr
J-GLOBAL ID：200901085536786779   Update date: Feb. 01, 2024

Goto Akira

ゴトウ アキラ | Goto Akira
Affiliation and department：
INSERM (French National Institute of Health) UPR9022-CNRS/M3i University of Strasbourg

About INSERM (French National Institute of Health) UPR9022-CNRS/M3i University of Strasbourg


Job title： Permanent research scientist
Homepage URL  (1)： https://ibmc.cnrs.fr/laboratoire/m3i/equipes/linflammation-chez-la-drosophile/
Research field  (3)： Entomology ,  Molecular biology ,  Applied molecular and cellular biology
Research keywords  (9)： RasV12 cells ,  RNA sequencing ,  RNA interference ,  Antiviral immune reaction ,  Innate immune signalling pathway ,  ショウジョウバエ ,  自然免疫 ,  Drosophila ,  Innate immunity
Research theme for competitive and other funds  (4)：
  • 2009 - 2010 Identification of novel defense factors using Luciferase expressing Listeria by RNAi screening.
  • 2007 - 2008 Screening of novel defense factors using highly sensitive Listeria infection reporter system
  • 1997 - 1997 ショウジョウバエを用いた自然免疫研究
  • 1997 - 1997 Innate immunity on Drosophila melanogaster
Papers (36)：
  • Akira Goto, Shanming Ji, Stanislava Chtarbanova, Takayuki Kuraishi. Editorial: Inflammatory and inflammatory-like responses in insects. Frontiers in Immunology. 2023. 14
  • Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann. Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type <i>Drosophila</i>. Journal of Innate Immunity. 2023. 442-467
  • Yangyang Zhu, Lei Liu, Chuchu Zhang, Chao Zhang, Tingting Han, Renjie Duan, Yiheng Jin, Huimin Guo, Kan She, Yihua Xiao, et al. Endoplasmic reticulum-associated protein degradation contributes to Toll innate immune defense in Drosophila melanogaster. Frontiers in Immunology. 2023. 13
  • Alexandre Cammarata-Mouchtouris, Adrian Acker, Akira Goto, Di Chen, Nicolas Matt, Vincent Leclerc. Dynamic Regulation of NF-κB Response in Innate Immunity: The Case of the IMD Pathway in Drosophila. Biomedicines. 2022. 10. 9. 2304-2304
  • Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, et al. cGMP signaling pathway that modulates NF-κB activation in innate immune responses. iScience. 2021. 24. 12. 103473-103473
ｍore...
MISC (6)：
  • Kiyoshi Okado, Akira Goto. Antiviral signalling pathway in Drosophila. 2021
  • Akira Goto, Kiyoshi Okado. Discovery of antiviral dSTING-dIKKβ-NF-κB signalling pathway and antiviral factor Nazo in Drosophila. Clinical Immunology & Allergology. 2019
  • Akira Goto, Kiyoshi Okado. Discovery of antiviral signalling pathway and new antiviral protein in Drosophila. First author's. 2018
  • 後藤彰, 矢野環, 寺島潤, 倉田祥一朗. 新規抗菌ペプチドDrosophila Listericinの同定. 生化学. 2010. 82. 7. 667
  • Goto, Akira. Identification of novel nuclear innate immune factor Akirin. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2008. 53. 9. 1144-1151
ｍore...
Lectures and oral presentations  (55)：
  • A time course transcriptomic analysis of host and injected oncogenic RasV12 cells in Drosophila.
    (2023)
  • Transcriptional responses of the host and tumors in the context of oncogenic RasV12 cell injection system in adult Drosophila melanogaster.
    (2023)
  • Discovery of novel antiviral dSTING/dIKKβ/NF-κB pathway in Drosophila.
    (7th Annual interdisciplinary academy: Summer school, Stream 6-Drug discovery section, University of South Africa (Invited lecture by Pr. Monde Ntwasa) 2019)
  • Discovery of novel antiviral dSTING/dIKKβ/NF-κB pathway in Drosophila
    (Invited seminar in Kyoto University. July 10th, Kyoto, Japan (Invitation by Pr. Masao Doi) 2019)
  • Discovery of novel antiviral dSTING/dIKKβ/NF-κB pathway in Drosophila.
    (Invited seminar in Kyoto University (Invitation by Pr. Osamu Takeuchi) 2019)
ｍore...
Works (6)：
  • ルシフェラーゼ発現リステリア菌を用いた宿主感染防御因子のRNAiスクリーニング
    2008 - 2009
  • ルシフェラーゼ発現リステリア菌を用いた宿主感染防御因子のRNAiスクリーニング
    2008 - 2009
  • リステリア菌感染の高感度検出レポーターシステムを用いた新規防御因子の探索
    2007 - 2009
  • リステリア菌感染の高感度検出レポーターシステムを用いた新規防御因子の探索
    2007 - 2009
  • 自家発光型リステリア菌を用いた宿主感染防御因子のRNAiスクリーニング探索
    2009 -
ｍore...
Education (2)：
  • 1996 - 2001 Nagoya University Graduate School of Bioagricultural Sciences
  • 1992 - 1996 Fukui Prefectural University Faculty of Biotechnology Department of Bioscience
Professional career (1)：
  • Bioagriculture (Nagoya University)
Work history (13)：
  • 2015/02 - 現在 Habilitation à diriger des recherches (HDR) in University of Strasbourg
  • 2012/10 - 現在 INSERM University of Strasbourg, CNRS du UPR9022, M3i (Modèles Insectes d’Immunité Innée) Research Scientist (Chargés de Recherche)
  • 2011/04 - 2012/09 University of Strasbourg, UPR9022 du CNRS, M3i (Modèles Insectes d’Immunité Innée) Postdoctral fellow
  • 2009 - 2011/03 Tohoku University Graduate School of Life Sciences
  • 2009 - 2009 Graduate School of Life Sciences, Tohoku University Global COE assistant professor
Show all
Awards (2)：
  • 2010 - JADCI 古田奨励賞
  • 2007 - Naito foundation The 36th Naito foundation for encouraging research
Association Membership(s) (5)：
日本生体防御学会 ,  日本比較免疫学会 ,  JSHDR (Japanese Society for Host Defense Research) ,  JADCI (The Japanese Association for Developmental & Comparative Immunology) ,  The Molecular Biology Society of Japan
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