Aihara Michiko

アイハラミチコ | Aihara Michiko

Affiliation and department：
Job title：学長
Homepage URL (1)： http://www.yokohama-dermatology.org/

Research field (3)： Immunology , Allergies and connective tissue disease , Dermatology

Research keywords (11)：皮膚アレルギー , 食物アレルギー , かゆみ , アトピー性皮膚炎 , 薬疹 , 薬物アレルギー , skin allergy , food allergy , atopic dermatitis , drug eruption , adverse drug reaction

Research theme for competitive and other funds (18)：

2016 - 2019 Aberrant expression of Caveolin-1 in psoriatic monocytes
2014 - 2018 Analysis of allergens related to severe reactions peach allergy
2014 - 2018 Development of a diagnostic method for severe cutaneous adverse reactions by genom biomarkers and their pathophysiological relevanceic
2016 - 2018 新規分子標的薬による皮膚障害の調査および重症化予防の研究
2016 - 2018 慢性そう痒性皮膚疾患の難治化機序の解明と新規治療薬の開発

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Papers (154)：

Natsumi Hama, Yuma Sunaga, Hirotaka Ochiai, Akatsuki Kokaze, Hideaki Watanabe, Michiko Kurosawa, Hiroaki Azukizawa, Hideo Asada, Yuko Watanabe, Yukie Yamaguchi, et al. Development and validation of a novel score to predict mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis: CRISTEN. J. Allergy Clin. Immunol. Pract. 2023
Suzuki M, Koshikawa S, Watanabe H, Inomata N, Yamaguchi Y, Aihara M, Sueki H. Elevated serum osteopontin levels in patients with severe cutaneous adverse drug reactions. J Dermatol. 2023. 50. 4. 536-540
Tomoya Watanabe, Yuko Watanabe, Noriko Ikeda, Michiko Aihara, Yukie Yamaguchi. Serum levels of C-C motif chemokine ligand 2 and interleukin-8 as possible biomarkers in patients with toxic epidermal necrolysis accompanied by acute respiratory distress syndrome. The Journal of dermatology. 2022
Miho Asami, Yasushi Ototake, Naoko Takamura, Yuko Watanabe, Michiko Aihara, Yukie Yamaguchi. Abnormal inflammatory traits and downregulated caveolin-1 expression in monocytes of psoriasis patients may be associated with psoriatic inflammation and atherosclerosis. Journal of dermatological science. 2022. 107. 2. 65-74
Yuma Sunaga, Natsumi Hama, Hirotaka Ochiai, Akatsuki Kokaze, Eun Seon Lee, Hideaki Watanabe, Michiko Kurosawa, Hiroaki Azukizawa, Hideo Asada, Yuko Watanabe, et al. Risk factors for sepsis and effects of pretreatment with systemic steroid therapy for underlying condition in SJS/TEN patients: Results of a nationwide cross-sectional survey in 489 Japanese patients. Journal of dermatological science. 2022. 107. 2. 75-81

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MISC (245)：

高橋沙希, 山川浩平, 石川秀幸, 福澤理映, 金岡美和, 池田信昭, 和田秀文, 相原道子, 加藤生真, 奥寺康司. 脱分化をきたし急速に増大した耳前部悪性黒色腫の1例. 日本皮膚科学会雑誌. 2019. 129. 6. 1355-1355
向所純子, 和田秀文, 佐藤愛, 小田香世子, 河野克之, 高野祥子, 松村舞衣, 加藤生真, 山中正二, 相原道子. 頸部に広範囲の暗赤色斑を認めた眼窩部導管癌の皮膚転移の1例. Skin Cancer. 2018. 33. 1. 7-12
東平麻維, 和田秀文, 向所純子, 渡邉裕子, 相原道子, 加藤生真, 松倉節子, 毛利忍. 左側腹部に生じた血管肉腫の1例. 日本皮膚科学会雑誌. 2018. 128. 3. 443-444
相原道子. 特集免疫アレルギー領域における指定難病スチーヴンス・ジョンソン症候群. アレルギーの臨床. 2018. 38. 8. 737-740
N. Takamura, Y. Yamaguchi, Y. Watanabe, M. Asami, N. Komitsu, M. Aihara. Downregulated Caveolin-1 expression in monocytes may contribute to the pathogenesis of psoriasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017. 137. 10. S250-S250

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Books (27)：

専門医でも聞きたい皮膚科診療100の質問
メディカルレビュー社 2017
今日の治療指針私はこう治療している TODAY’S THERAPY 2017
医学書院 2017
感染症専門医テキスト第I部解説編(日本感染症学会編)
南江堂 2017
1 重篤な即時型薬疹と遅延型薬疹
薬疹の診断と治療アップデート重症薬疹を中心に(塩原哲夫編), 医薬ジャーナル社(大阪) 2016
2 臨床症状および病理組織学的所見による分類
薬疹の診断と治療アップデート重症薬疹を中心に(塩原哲夫編), 医薬ジャーナル社(大阪) 2016

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Lectures and oral presentations (47)：

Downregulated Caveolin-1 expression in circulating monocytes may contribute to the pathogenesis of psoriasis
(The 42nd Annual Meeting of the Japanese Society for Investigative Dermatology (JSID) 2017)
Downregulated Caveolin-1 expression in monocytes may contribute to the pathogenesis of psoriasis
(The European Society for Dermatological Reseach (ESDR) 2017)
Pro-fibrotic Phenotype of Human Skin Fibroblasts Induced by Periostin via Modulating TGF-β Signaling
(The European Society for Dermatological Reseach (ESDR) 2017)
ollagen tripeptide may modulate inflammation of atopic dermatitis
(2017 Annual Meeting 2017)
Clinical Significance of Serum Levels of Anti-Transcriptional Intermediary Factor 1-γ Antibody in Patients with Dermatomyositis
(2017 ACR/ARHP Annual Meeting 2017)

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Education (3)：

- 1980 Yokohama City University
- 1980 Yokohama City University
- 1980 Yokohama City University Faculty of Medicine

Professional career (1)：

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Committee career (7)：

2021/11 - 現在文部科学省科学技術・学術審議会臨時委員会(大学研究強化委員会)
2021/04 - 現在文部科学省中央教育審議会臨時委員(大学分科会)
2021/08 - 2022/03 横浜文化賞選考委員会選考委員長
2017/10 - 2021/06 内閣府食品安全委員会専門委員
2017/03 - 2021/02 厚生労働省医道審議会医師分科会(医師臨床研修部会)臨時委員

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Awards (4)：

2018 - Most Cited Paper 2017 Impact Factor Period The Jpurnal of Dermatology Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis. volume 42, Issue 8, Pages 768-777, August 2015
2014 - Aihara M:JD Most downloaded paper in 2013. Pharmacogenetics of cutaneous adverse drug reactions,Volume 38, Issue 3, pages 246-254, March 2011
2014 - Aihara M:JD Most cited paper 2013 Impact Factor period. Pharmacogenetics of cutaneous adverse drug reactions,Volume 38, Issue 3, pages 246-254, March 2011
1992 - 横浜市立大学医学会医学研究奨励賞

Association Membership(s) (6)：

日本乾癬学会 , 日本皮膚免疫アレルギー学会 , 日本研究皮膚科学会 , 日本アレルギ-学会 , アメリカ皮膚科学会(American Academy of Dermatology , 日本皮膚科学会

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