2011 - 2013 Pleiotropic effects of afadin, an scaffold molecule, on regulation of cellular functions
2009 - 2010 Roles of the nectin-afadin system in epithelial-mesenchymal and mesenchymal-epithelial transitions
2008 - 2009 細胞の極性形成における低分子量Gタンパク質の役割と作用機構
2005 - 2009 Role of cell adhesion signaling in the abnormal cell polarization of cancer cells
2007 - 2008 Physical and functional interaction among nectin, integrin, and platelet-derived growth factor
2006 - 2007 細胞間接着における低分子量Gタンパク質の役割と作用機構
2005 - 2006 新規接着分子ネクチンとインテグリンとの協調作用による細胞間接着の形成機構
2000 - 2004 細胞増殖のシグナリング機構
がん・心血管系疾患におけるシグナル伝達機構と細胞間相互作用
Molecular mechanism of cell-cell interaction and signal transduction in cancer biology and cardiovascular diseases
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Papers (97):
Imamura-Uehara Y, Yasuda-Yamahara M, Kuwagata S, Yamahara K, Yoshibayashi M, Tanaka-Sasaki Y, Shimizu A, Ogita H, Chin-Kanasaki M, Kume S. Establishment of a novel mouse model of renal artery coiling-based chronic hypoperfusion-related kidney injury. Biochem Biophys Rep. 2024. 37. 101607
Takashima S, Okamura E, Ichiyama Y, Nishi K, Shimizu A, Watanabe C, Muto M, Matsumoto S, Tsukiyama-Fujii S, Tsukiyama T, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Exp Anim. 2024. 73. 93-100
Joanne Ern Chi Soh, Akio Shimizu, Akira Sato, Hisakazu Ogita. Novel cardiovascular protective effects of RhoA signaling and its therapeutic implications. Biochemical Pharmacology. 2023. 218. 115899-115899
Sato A, Tsukiyama T, Komeno M, Iwatani C, Tsuchiya H, Kawamoto I, Murase M, Nakagawa T, Itagaki I, Seita Y, et al. Generation of a familial hypercholesterolemia model in non-human primate. Sci Rep. 2023. 13. 15649
Nakai S, Tateoka Y, Miyaguchi Y, Takahashi M, Ogita H. Associations between habitual dietary behaviors and glutamic acid levels in human milk. J Hum Lact. 2023. 39. 315-324
Akio Shimizu, Hisakazu Ogita. Critical role of dipeptidyl peptidase III in cleavage of angiotensin II and its clinical implication. Seikagaku. 2017. 89. 449-452
The developing embryo requires endothelial RhoA for its angiogenesis and survival
(日本生化学会近畿支部例会(優秀発表賞受賞) 2023)
Employing static electric machine to suppress the progression of diabetic kidney disease by minimizing type 2 diabetes-induced oxidative stress
(日本生化学会近畿支部例会 2023)
Afadin-mediated regulation of vascular smooth muscle cell contraction via the Gq-phospholipase Cβ axis to enhance calcium signaling
(日本生化学会近畿支部例会(優秀発表賞受賞) 2023)
1999 - 2003 Osaka University Graduate School of Medicine
1989 - 1995 Osaka University Faculty of Medicine Medical School
Professional career (1):
MD, PhD (Osaka University)
Work history (8):
2011 - 現在 Shiga University of Medical Science Professor
2019 - 2023 Shiga University of Medical Science Central Research Laboratory
2008 - 2011 Kobe University Graduate School of Medicine Associate Professor
2004 - 2008 Osaka University Graduate School of Medicine Assistant Professor
2003 - 2004 Harvard University Medicine Postdoctoral Fellow
1997 - 2000 Osaka Prefectural General Hospital Division of Cardiology Resident
1996 - 1997 Osaka Prefectural General Hospital
1995 - 1996 Osaka University Hospital
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Awards (6):
2023 - 日本循環器学会国際留学生YIA指導者賞
2022 - 日本循環器学会国際留学生YIA指導者賞
2012 - 日本医師会医学研究奨励賞
2002 - 日本血管細胞生物学会Young Investigator’s Award
2002 - American College of Cardiology, Young Investigator’s Award
2001 - 日本心臓病学会Young Investigator's Award
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Association Membership(s) (11):
日本医師会
, 日本血管生物医学会
, 日本医学教育学会
, American Society for Biochemistry and Molecular Biology
, American Heart Association
, 日本癌学会
, 日本生化学会
, 日本心臓病学会
, 日本循環器学会
, 日本内科学会
, American Society for Cell Biology