Rchr
J-GLOBAL ID:200901090595037490   Update date: Mar. 31, 2024

Nakatani Kazuhiko

ナカタニ カズヒコ | Nakatani Kazuhiko
Affiliation and department:
Research field  (10): Biochemistry ,  Functional solid-state chemistry ,  Synthetic organic chemistry ,  Bioorganic chemistry ,  Structural/physical organic chemistry ,  Molecular biochemistry ,  Systems genomics ,  Genomics ,  Nanobioscience ,  Nanomaterials
Research keywords  (1): ミスマッチ結合分子 SNP検出 ドラッグの分子設計 核酸ードラッグ複合体 トリプレットリピート
Research theme for competitive and other funds  (45):
  • 2022 - 2025 Elucidation of the binding pathway of mismatch-binding molecules to abnormally elongated repeat sequences and their shortening-inducing effects
  • 2019 - 2022 Challenge in computational science toward the identification of the reaction pathway for the formation of nucleic acids-small molecule complexes
  • 2019 - 2022 リピート配列を特異的に化学修飾するリピート結合分子の創成
  • 2016 - 2019 Development of novel microRNA detection system
  • 2014 - 2019 Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding Molecules
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Papers (129):
  • Lu Ni, Takeshi Yamada, Kazuhiko Nakatani. Utility of oligonucleotide in upregulating circular RNA production in a cellular model. 2024
  • Takeshi Yamada, Shuhei Sakurabayashi, Noriaki Sugiura, Hitoshi Haneoka, Kazuhiko Nakatani. NMR analysis of 15N-labeled naphthyridine carbamate dimer (NCD) to contiguous CGG/CGG units in DNA. Chemical Communications. 2024
  • Qingwen Chen, Takeshi Yamada, Asako Murata, Ayako Sugai, Yasuyuki Matsushita, Kazuhiko Nakatani. A machine learning approach toward generating the focused molecule library targeting CAG repeat DNA. Digital Discovery. 2024
  • Eitaro Murakami, Masayuki Nakamori, Kazuhiko Nakatani, Tomonori Shibata, Kazuki Tainaka. Intracerebral Distribution of CAG Repeat-Binding Small Molecule Visualized by Whole-Brain Imaging. Bioconjugate chemistry. 2023. 34. 12. 2187-2193
  • Qingwen Chen, Takeshi Yamada, Koichi Miyagawa, Asako Murata, Mitsuo Shoji, Kazuhiko Nakatani. A New Small Molecule DoNA Binding to CAG Repeat RNA. Bioorganic & Medicinal Chemistry. 2023
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MISC (179):
  • 櫻林修平, 山田剛史, 中谷和彦. 7位修飾ナフチリジンカルバメートダイマーの合成と結合特性. 日本化学会春季年会講演予稿集(CD-ROM). 2019. 99th
  • 三木翔太, 三木翔太, 山田剛史, 中谷和彦. RNA切断活性をもつミスマッチ結合性リガンドの開発. 日本化学会春季年会講演予稿集(CD-ROM). 2017. 97th
  • Jinxing Li, Jun Matsumoto, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani. Cover Picture: A Ligand That Targets CUG Trinucleotide Repeats (Chem. Eur. J. 42/2016). Chemistry - A European Journal. 2016. 22. 42. 14757
  • Fumie Takei, Kazuhiko Nakatani. The Chemistry of PCR Primers: Concept and Application. ISRAEL JOURNAL OF CHEMISTRY. 2013. 53. 6-7. 401-416
  • 小田部尭広, 村田亜沙子, 武井史恵, 中谷和彦. RNAバルジ結合性小分子の合成とDicer切断反応の阻害剤としての利用. 日本化学会講演予稿集. 2013. 93rd. 3
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Education (4):
  • - 1987 Osaka City University
  • - 1987 Osaka City University Graduate School, Division of Natural Science
  • - 1982 Osaka City University Faculty of Science
  • - 1982 Osaka City University Faculty of Science
Professional career (1):
  • Doctor of Science
Committee career (1):
  • 1993 - 日本化学会 トピックス委員
Awards (7):
  • 2008 - 日本化学会学術賞
  • 2008 - 市村学術賞 貢献賞
  • 2008 - 大阪科学賞
  • 2006 - 大阪大学研究・教育功績賞
  • 2005 - 第19回日本IBM科学賞
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Association Membership(s) (4):
光化学協会 ,  有機合成化学協会 ,  アメリカ化学会 ,  日本化学会
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