Research keywords (6):
Bioinorganic chemistry
, Bioorganic chemistry
, Reactive oxygen species
, Arsenic
, Trace element
, Selenium
Research theme for competitive and other funds (15):
2022 - 2025 Elucidation of biosynthetic pathway of selenosugars
2021 - 2024 Toxicological significance of metal biogenic nanoparticles
2018 - 2021 Molecular mechanisms underlying the formation of bioorganometallic bond for metal toxicology
2017 - 2020 Synthesis and biological evaluation of selenoneine, naturally occurring selenium containing compound
2016 - 2019 Speciation and toxicological study of antimony in the environmental water in eastern and mid-southern China
2015 - 2018 Elucidation of the metabolism and toxicity mechanism of arsenolipids by analytical chemistry techniques
2014 - 2017 Metallome analysis with cellular differentiation
2014 - 2017 Development of novel caged compound bearing off/on switch of light sensitivity
2014 - 2016 Development of dual-modality SPECT/fluorescent probe
2011 - 2013 Development of SPECT probe for oxidative stress imaging
2010 - 2011 生体内redox stateの可視化のためのSPECTプローブの開発と応用
2007 - 2009 Mechanisms underlying circulation of selenium in Biosphere
2007 - 2008 Mechanism of intracellular reactive oxygen species generation by exposure of trivalent arsenic compounds
2004 - 2007 Metallomics of bio-trace elements : Copper, selenium and arsenic
2005 - 2006 ヒ素による酸化ストレス誘導機構のメタロミクスに基づく解明
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Papers (79):
Yasunori Fukumoto, Rin Kyono, Yuka Shibukawa, Yu-ki Tanaka, Noriyuki Suzuki, Yasumitsu Ogra. Differential molecular mechanisms of substrate recognition by selenium methyltransferases, INMT and TPMT, in selenium detoxification and excretion. Journal of Biological Chemistry. 2024. 300. 2. 105599-105599
Yasunori Fukumoto, Dongyue Wang, Yu-ki Tanaka, Noriyuki Suzuki, Yasumitsu Ogra. Acute methylmercury exposure induces inactivation of ATR pathway and enhancement of DNA replication stress through degradation of Rad17. Metallomics Research Online ISSN : 2436-5173. 2023. 3. 2. 21-28
Yasumitsu Ogra, Nicole Roldán, Marcelo Verdugo, Alexis A Gonzalez, Noriyuki Suzuki, Waldo Quiroz. Distribution, metabolism, and toxicity of antimony species in wistar rats. A bio-analytical approach. Environmental toxicology and pharmacology. 2023. 100. 104160-104160
Yasumitsu Ogra, Yu-Ki Tanaka, Noriyuki Suzuki. Recent advances in copper analyses by inorganic mass spectrometry. Journal of clinical biochemistry and nutrition. 2022. 71. 1. 2-6
2018/11 - The Japanese Society of Toxicology research encouragement award
Association Membership(s) (5):
The Pharmaceutical Society of Japan
, Japanese Society for Molecular Imaging
, Japanese Society for Chemical Biology
, Japan Society for Biomedical Research on Trace Elements
, The Japanese Society of Toxicology