Rchr
J-GLOBAL ID：200901093212195347
Update date: Jan. 31, 2024
Ohi Hiroaki
オオイ ヒロアキ | Ohi Hiroaki
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Affiliation and department：
Toho University Faculty of Pharmaceutical Sciences
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Detailed information
Job title：
Associate Professor
Research field (1)：
Clinical pharmacy
Research keywords (2)：
薬学教育
, Biochemistry of drug-metabolizing enzymes
Research theme for competitive and other funds (11)：
2005 - 2006 Relationship between AhR-related proteins and neurodegenerative diseases
2000 - 2001 Correlationship between induction of drug-metabolizing enzymes and onset of neurodegenerative disorders
1999 - 2001 Aberrant intracellular signaling in the pathogenesis of muscular dystrophy
1997 - 1999 Production of muscular dystrophy mice by molecular engineering
1997 - 1998 脳内チトクロームP450の神経疾患に与える影響に関する研究
1993 - 1993 光学活性化合物を用いた薬物代謝酵素の多型性に関する研究
1989 - 1989 ヒト胎児肝に特異的に存在するグルタチオンS-トランスフェラ-ゼに関する研究
1988 - 1989 Regulation of Sex-Specific Forms of Cytochrome P-450 : Cytochrome P-450 in Liver Microsomes of Hamsters
1988 - 1988 癌原・変異原物質を活性化するチトクロームP-450の発現と発癌リスクの予測
薬学教育
Study of induction mechanism of cytochrome P450
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MISC (18)：
Y Fujita, H Ohi, N Murayama, K Saguchi, S Higuchi. Identification of multiple cytochrome P450 genes belonging to the CYP4 family in Xenopus laevis: cDNA cloning of CYP4F42 and CYP4V4. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY. 2004. 138. 2. 129-136
N Murayama, K Saguchi, R Mentele, MT Assakura, H Ohi, Y Fujita, ACM Camargo, S Higuchi, SMT Serrano. The unusual high molecular mass of Bothrops protease A, a trypsin-like serine peptidase from the venom of Bothrops jararaca, is due to its high carbohydrate content. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. 2003. 1652. 1. 1-6
H Ohi, Y Fujita, M Miyao, K Saguchi, N Murayama, S Higuchi. Molecular cloning and expression analysis of the aryl hydrocarbon receptor of Xenopus laevis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003. 307. 3. 595-599
Y Sunada, H Ohi, A Hase, H Ohi, T Hosono, S Arata, S Higuchi, K Matsumura, T Shimizu. Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity. HUMAN MOLECULAR GENETICS. 2001. 10. 3. 173-178
N Murayama, GH Michel, R Yanoshita, Y Samejima, K Saguchi, H Ohi, Y Fujita, S Higuchi. cDNA cloning of bradykinin-potentiating peptides-C-type natriuretic peptide precursor, and characterization of the novel peptide Leu3-blomhotin from the venom of Agkistrodon blomhoffi. EUROPEAN JOURNAL OF BIOCHEMISTRY. 2000. 267. 13. 4075-4080
ｍore...
Education (4)：
- 1985 The University of Tokyo
- 1985 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1983 The University of Tokyo Faculty of Pharmaceutical Sciences
- 1983 The University of Tokyo Faculty of Pharmaceutical Science
Professional career (1)：
(BLANK)
Association Membership(s) (1)：
日本薬学会
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