Rchr
J-GLOBAL ID：200901097584385652   Update date: Apr. 04, 2024

TANABE Shihori

タナベ シホリ | TANABE Shihori
Affiliation and department：
National Institute of Health Sciences

About National Institute of Health Sciences


Job title： Senior Researcher
Research field  (2)： Pharmaceuticals - health and biochemistry ,  Biological, health, and medical informatics
Research keywords  (7)： Epithelial mesenchymal transition ,  Gene expression ,  Stem cell ,  Cancer ,  Molecular network pathway ,  Pharmaceutical science ,  Molecular cellular biology
Research theme for competitive and other funds  (7)：
  • 2021 - 2024 Study of molecular network pathway analysis on prediction and risk assessment of pharmaceutics
  • 2021 - 2024 Elucidation on regulation mechanism of RNA viral infection molecular network in diffuse- and intestinal-type gastric cancer
  • 国際機関安全情報に関する研究
  • 細胞治療薬に関する研究
  • Network analysis of exosome RNA and gene expression in silico
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Papers (102)：
  • Amgad Abdallah, Nada Adel, Am El Kerdawy, Shihori Tanabe, Frédéric Andrès, Andreas Pester, Hesham H. Ali. Geom-SAC: Geometric multi-discrete soft actor critic with applications in de novo drug design. IEEE Access. 2024. 12. 45519-45529
  • Amgad A. Mahmoud, Nada A. Alyan, Ahmed M. El Kerdawy, Shihori Tanabe, Frédéric Andrès, Andreas Pester, Hesham H. Ali. A New Graph-Based Reinforcement Learning Environment for Targeted Molecular Generation and Optimization. ICSIE '23: Proceedings of the 2023 12th International Conference on Software and Information Engineering. 2024. November 2023. 52-57
  • Shihori Tanabe. Role of eIF2 signaling in cancer and its relationship with coronavirus. Advances in Clinical and Medical Research. 2024. 5. 1. 1-3
  • Maranda Esterhuizen, Chang-Beom Park, Young Jun Kim, Tae-Young Kim, Hakwon Yoon, Frederic Andres, Rosalia Rodriguez-Rodriguez, Shihori Tanabe. A Perspective on the Role of Physiological Stresses in Cancer, Diabetes and Cognitive Disease as Environmental Diseases. Frontiers in Molecular Biosciences. 2023. 10. 1274221
  • Shihori Tanabe, Eger Boonstra, Taehun Hong, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Hiroshi Yokozaki, Ed Perkins, Hiroki Sasaki. Molecular Networks of Platinum Drugs and Their Interaction with microRNAs in Cancer. Genes. 2023. 14. 11. 2073
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MISC (26)：
  • Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Akihiko Hirose, Edward J Perkins, Hiroshi Yokozaki, Hiroki Sasaki. Artificial Intelligence-Based Models to Predict the Activation State of Molecular Pathway in Diseases. The 37th Annual Conference of the Japanese Society for Artificial Intelligence, 2023. 2023. 2U1-IS-1b-04
  • Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Akihiko Hirose, Edward J Perkins, Hiroshi Yokozaki, Hiroki Sasaki. The development of AOP298 "Increases in cellular reactive oxygen species leading to human treatment-resistant gastric cancer". The Journal of Toxicological Sciences. 2023. 48. Suppl. S77-S77
  • 田邊思帆里, カデール サビーナ, 小野竜一, カブラル オラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. がん幹細胞分子ネットワークにおける微小環境RNA制御. 日本再生医療学会総会(Web). 2023. 22nd
  • 田邊思帆里, カデール サビーナ, 小野竜一, カブラル オラシオ, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The master regulators of causal networks in intestinal- and diffuse-type gastric cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 田邊思帆里, QUADER Sabina, 小野竜一, CABRAL Horacio, 青柳一彦, 広瀬明彦, 横崎宏, 佐々木博己. The relationship between coronavirus pathogenesis pathway and EIF2 signaling. 日本薬学会年会要旨集(Web). 2023. 143rd
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Books (8)：
  • Abnormal Glycosylation in Cancer Cells and Cancer Stem Cells as a Therapeutic Target
    Springer 2023 ISBN:9783031129742
  • Microenvironment of Cancer Stem Cells
    Springer 2023 ISBN:9783031129742
  • Epithelial-Mesenchymal Transition and Cancer Stem Cells
    Springer 2023 ISBN:9783031129742
  • Adverse Outcome Pathways in reproductive and developmental toxicology
    Elsevier Inc./Academic Press 2022 ISBN:9780323897730
  • Introductory Chapter: Invitation for Peripheral Membrane Proteins
    InTech 2018 ISBN:9781789235135
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Lectures and oral presentations  (138)：
  • Development of AOPs related to epithelial-mesenchymal transition (EMT) network alteration induced by gene expression dynamism and coronavirus
    (The 144th Annual Meeting of the Pharmaceutical Society of Japan 2024)
  • Updates on Guide for Coaches
    (SKIG meeting 2024)
  • Regulatory mechanism of molecular networks related to cancer stem cells
    (The 23rd Congress of the Japanese Society for Regenerative Medicine 2024)
  • Causal networks in intestinal- and diffuse-type stomach adenocarcinoma and the relation to RNA virus infection
    (The 63rd Annual Meeting of the Society of Toxicology 2024 2024)
  • An approach for applying ChatGPT in AOP development, and umbrella KEs related to the Mystery of ROS
    (SKIG meeting 2024)
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Education (4)：
  • 2000 - 2005 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 2002 - 2004 University of Illinois at Chicago College of Medicine Department of Pharmacology
  • 1998 - 2000 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 1996 - 1998 The University of Tokyo Faculty of General Education Science II
Professional career (1)：
  • PhD (University of Tokyo)
Work history (6)：
  • 2016/04 - 現在 National Institute of Health Sciences Division of Risk Assessment, Center for Biological Safety and Research Senior Researcher
  • 2011/04 - 2016/03 National Institute of Health Sciences Director for Planning and Coordination’s In Concurrent
  • 2010/04 - 2016/03 National Institute of Health Sciences Division of Safety Information on Drug, Food and Chemicals Senior Researcher
  • 2009/04 - 2010/09 Ministry of Health, Labour and Welfare Health Sciences Division, Minister’s Secretariat In Concurrent
  • 2006/02 - 2010/03 National Institute of Health Sciences Division of Cellular and Gene Therapy Products Researcher
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Committee career (25)：
  • 2022/05 - 現在 Special Issue "Advances in Molecular Mechanisms of Gastrointestinal Tumors" Guest Editor
  • 2022/05 - 現在 Frontiers in Oncology - Molecular and Cellular Oncology Associate Editor
  • 2021/04 - 現在 Advances In Clinical And Medical Research Editor-in-Chief
  • 2020 - 現在 CIAO (Modelling the Pathogenesis of COVID-19 Using the Adverse Outcome Pathway Framework) Member
  • 2020 - 現在 OECD AOP Development External Review Subgroup Co-lead
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Awards (1)：
  • 2002 - 病態代謝研究会 第34回海外留学補助金
Association Membership(s) (13)：
THE JAPANESE SOCIETY FOR ARTIFICIAL INTELLIGENCE ,  JAPANESE SOCIETY OF FOOD CHEMISTRY ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  SOCIETY FOR REGULATORY SCIENCE OF MEDICAL PRODUCTS ,  JAPAN HUMAN PROTEOME ORGANISATION ,  THE JAPANESE CANCER ASSOCIATION ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  Society of Toxicology
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