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J-GLOBAL ID：200901098289880206   Update date: Apr. 02, 2024

Wanaka Akio

ワナカ アキオ | Wanaka Akio
Affiliation and department：
Graduate School of Medical Safety Management, Jikei University of Health Care Sciences

About Graduate School of Medical Safety Management, Jikei University of Health Care Sciences


Job title： Professor
Homepage URL  (1)： https://graduate.juhs.ac.jp/
Research field  (3)： Anatomy ,  Neuroscience - general ,  Neuroanatomy and physiology
Research keywords  (17)： NGF ,  Allodynia ,  Macrophage ,  OASIS ,  Intracellular membrane traffic ,  Pain ,  Tripartite synapse ,  Astrocyte ,  損傷修復 ,  グリア細胞 ,  ストレス応答 ,  tissue remodelling ,  Differentiation regeneration ,  Transcription factor ,  Stress response ,  Glia ,  Neuron
Research theme for competitive and other funds  (52)：
  • 2021 - 2024 真皮マクロファージにおける新規の炎症疼痛制御因子の機能解析
  • 2018 - 2023 A novel signaling eregulates patterning and growth in the face.
  • 2019 - 2022 Identification of pain regulators by forward genetic screening using pain-insensitive mice.
  • 2016 - 2020 Generation of inner ear hair cells toward cell transplantation using pluripotent stem cells
  • 2015 - 2019 Novel signal network controls craniofacial morphogenesis.
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Papers (192)：
  • Tatsuhide Tanaka, Hiroaki Okuda, Ayami Isonishi, Yuki Terada, Masahiro Kitabatake, Takeaki Shinjo, Kazuya Nishimura, Shoko Takemura, Hidemasa Furue, Toshihiro Ito, et al. Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway. Nature Immunology. 2023. 24. 3. 439-451
  • Shoko Takemura, Ayami Isonishi, Noriko Horii-Hayashi, Tatsuhide Tanaka, Kouko Tatsumi, Takashi Komori, Kazuhiko Yamamuro, Mariko Yamano, Mayumi Nishi, Manabu Makinodan, et al. Juvenile social isolation affects the structure of the tanycyte-vascular interface in the hypophyseal portal system of the adult mice. Neurochemistry international. 2023. 162. 105439-105439
  • Kazuki Nakahara, Hiroaki Okuda, Ayami Isonishi, Yoshie Kawabe, Tatsuhide Tanaka, Kouko Tatsumi, Akio Wanaka. Amino acid transporter Asc-1 (SLC7A10) expression is altered in basal ganglia in experimental Parkinsonism and L-dopa-induced dyskinesia model mice. Journal of chemical neuroanatomy. 2022. 127. 102191-102191
  • Akio Wanaka. Special Issue for the JSN/APSN/ISN 2022 Meeting. Neurochemical research. 2022
  • Yoshie Kawabe, Tatsuhide Tanaka, Ayami Isonishi, Kazuki Nakahara, Kouko Tatsumi, Akio Wanaka. Characterization of Glial Populations in the Aging and Remyelinating Mouse Corpus Callosum. Neurochemical research. 2022
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MISC (211)：
  • 田中達英, 奥田洋明, 和中明生. Dermal macrophages set pain sensitivity. 月刊臨床免疫・アレルギー科. 2024. 81. 1
  • 田中 達英, 奥田 洋明, 和中 明生. 皮膚マクロファージによる痛み感受性の制御-Dermal macrophages set pain sensitivity. 臨床免疫・アレルギー科 = Clinical immunology & allergology / 臨床免疫・アレルギー科編集委員会 編. 2024. 81. 1. 58-63
  • 田中達英, 奥田洋明, 寺田雄紀, 新城武明, 西村和也, 石西綾美, 竹村晶子, 辰巳晃子, 和中明生. 痛覚鈍麻マウスの順遺伝学スクリーニングによる新規疼痛候補遺伝子の同定. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2020. 125th
  • 竹村晶子, 石西綾美, 田中達英, 奥田洋明, 辰巳晃子, 和中明生. 中枢神経系におけるsorting nexin25の発現分布と脳由来神経栄養因子受容体の発現調節における役割. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2020. 125th
  • 辰巳晃子, 石西綾美, 山崎美和子, 河邉良枝, 森田(竹村)晶子, 中原一貴, 奥田洋明, 田中達英, 和中明生. Olig2アストロサイトの脳内分布と抑制性シナプスとの関与. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2019. 124th
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Education (2)：
  • 1984 - 1988 Osaka University Graduate School of Medicine
  • 1977 - 1983 Osaka University School of Medicine
Professional career (1)：
  • 医学博士 (大阪大学)
Work history (6)：
  • 2024/04 - 現在 Graduate School of Medical Safety Management, Jikei University of Health Care Sciences Professor
  • 2002/04 - 2024/03 Nara Medical University Department of Anatomy and Neuroscience Professor
  • 1995/12 - 2002/03 Fukushima Medical University Research Institute of Biosignal Transduction Department of Cell Science Professor
  • 1993/04 - 1995/11 Osaka University School of Medicine Second Department of Anatomy Associate Professor
  • 1988/04 - 1993/09 Osaka Univeristy School of Medicine Second Department of Anatomy Assistant Profesoor
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Awards (1)：
  • 1995/04 - Japanese Association of Anatomists Young Investigator Award The roles of Heparin-binding Growth Factor in the development of the Central Nervous System
Association Membership(s) (5)：
Asian Pacific Society for Neurochemistry ,  The International Society for Neurochemistry ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPANESE ASSOCIATION OF ANATOMISTS
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