Research field (2)：
Gastroenterology
, Gastroenterology
Research keywords (2)：
消化器内科学
, Gastroenterology
Research theme for competitive and other funds (27)：
2021 - 2024 Immunonutritional approach for innate immune dysregulation in metabolic dysfunction-associated fatty liver disease
2020 - 2023 Mechanism of enhanced hepatotoxicity through fatty acid metabolic imbalance in the progression of fatty liver disease
2017 - 2020 The impact of lipid composition alteration via beta-oxidation failure on the pathophysiological linkage between nonalcoholic steatohepatitis and sarcopenia
2016 - 2019 Development of an early diagnosis method targeting nuclear matrix protein for autophagy-related digestive disorder disease
2015 - 2018 Palmitic acid elicits insulin resistance and oxidative cell injury through clusterization of lipid rafts in murine hepatocytes.
2015 - 2018 代謝性脂肪肝炎の基盤病態としての自然免疫・代謝連関と治療ストラテジー
2012 - 2015 The new strategy of steatohepatitis targeting alteration of epigenetic regulation
2012 - 2015 New therapeutic strategy to non-alcoholic liver disease targeting on autophagy
2012 - 2015 脂肪性肝疾患における免疫代謝調節機構の解明と免疫栄養療法の確立
2011 - 2013 Novel biomarker for evaluation of autophagic dysfunction in the liver
2009 - 2012 自然免疫機構による肝臓の代謝機能モデュレーションと脂肪性肝炎の病態形成機序
2009 - 2011 Central role of autophagy in the pathogenesis of gastrointestinal and hepatic diseases.
2006 - 2007 Role of lipid and oxidative stress on carcinogenesis in the digestive system
2004 - 2005 消化管・肝機能枢軸から見た薬物性肝障害機序の解明
2003 - 2005 Genetic Manipulation of Sinusoidal Endothelial Cells
2003 - 2005 Investigation of pathophysiology and therapeutic strategies for metabolic syndrome-related steatohepatitis
2002 - 2004 Inverse genomicsを用いた肝線維化に関わる遺伝子の網羅的探索
2001 - 2003 肝臓におけるleptinの産生およびその病態生理的意義
2000 - 2002 Innate immune response to gut-derived bacterial toxins in gastrointestinal andhepatic disorders
2000 - 2001 ROLE OF SENESCENCE MARKER PROTEIN-30 (SMP30) IN HEPATOCYTE APOPTOSIS
1999 - 2001 Amino acids as immuno-moduratory nutrients: therapeutic approaches for gastrointestinal and hepatic disorders.
Mechanism of hepatic Fibrogenesis
Mechanism of alcohol.induced liver injury.
進行中の研究課題・終了した研究課題
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Papers (273)：
Akira Uchiyama, Kazuyoshi Kon, Satoshi Sakuma, Toshifumi Sato, Maki Morinaga, Hiroo Fukada, Hisafumi Yamagata, Reiko Yaginuma, Kyoko Fukuhara, Shunhei Yamashina, et al. Hepatic steatosis and skeletal muscle alterations during the COVID-19 lockdown in a cohort of patients with chronic liver disease in Japan. Hepatology research : the official journal of the Japan Society of Hepatology. 2023
Akira Uchiyama, Shunhei Yamashina, Toshifumi Sato, Satoshi Sakuma, Yuichi Tomiki, Hiroyuki Isayama, Akihito Nagahara, Kenichi Ikejima. Benefit of an action camera in endoscopy education for medical students under COVID-19. BMC medical education. 2023. 23. 1. 693-693
1996 - 1997 University of North Carolina at Chapel Hill School of Medicine Department of Internal Medicine
1994 - 1996 University of North Carolina at Chapel Hill School of Medicine Department of Pharmacology
1992 - 1996 Juntendo University Graduate School of Medicine Department of Gastroenterology
- 1996 Juntendo University Graduate School, Division of Medicine
1983 - 1989 Juntendo University School of Medicine
- 1989 Juntendo University Faculty of Medicine
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Professional career (1)：
(BLANK)
Work history (2)：
2017/11 - 現在 Juntendo University Graduate School of Medicine Department of Gastroenterology Professor
2016/11 - 2017/10 Juntendo University School of Medicine Department of Gastroenterology Senior Associate Professor
Association Membership(s) (5)：
JAPANESE MEDICAL SOCIETY OF ALCOHOL AND ADDICTION STUDIES
, JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY
, THE JAPAN SOCIETY OF HEPATOLOGY
, JAPANESE SOCIETY OF GASTROENTEROLOGY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
