Yagisawa Hitoshi

• 2001 - Structure and function of p122RhoGAP/DLC-1 anti-oncogne product.
• 細胞運動におけるリン脂質の役割に関する研究
• ホスホリパーゼCアイソザイムの構造と機能に関する研究
• 高血圧素因の分子生物学的解析
• Study on the Mechanism of phospholipid-cytoskeleton interaction
Structural and Functional Studies on Phospholipase C Isozymes
Molecular Biological Study on Pathogenesis of Hypertension

• M Okada, T Ishimoto, Y Naito, H Hirata, H Yagisawa. Phospholipase C delta(1) associates with importin beta 1 and translocates into the nucleus in a Ca2+-dependent manner. FEBS LETTERS. 2005. 579. 22. 4949-4954
• M Okada, T Ishimoto, Y Naito, H Hirata, H Yagisawa. Phospholipase C delta(1) associates with importin beta 1 and translocates into the nucleus in a Ca2+-dependent manner. FEBS LETTERS. 2005. 579. 22. 4949-4954
• K Harada, H Takeuchi, M Oike, M Matsuda, T Kanematsu, H Yagisawa, KI Nakayama, K Maeda, M Hirata. Role of PRIP-1, a novel Ins(1,4,5)P-3 binding protein, in Ins(1,4,5)P-3-mediated, Ca2+ signaling. JOURNAL OF CELLULAR PHYSIOLOGY. 2005. 202. 2. 422-433
• Kae Harada, Hiroshi Takeuchi, Masahiro Oike, Miho Matsuda, Takashi Kanematsu, Hitoshi Yagisawa, Kei-Ichi I. Nakayama, Katsumasa Maeda, Christophe Erneux, Masato Hirata. Role of PRIP-1, a novel Ins(1,4,5)P3 binding protein, in Ins(1,4,5)P3-mediated Ca2+ signaling. Journal of Cellular Physiology. 2005. 202. 2. 422-433
• Necleocytoplasmic shuttling of phospholipase C-δ1 - A link to Ca2+. J Cel. Biochem. 2005. in press

ｍore...

• 免疫抑制剤(シクロプロジギオシンまたはその塩を有効成分として含有するもの)
• 医薬組成物(イノシトール結合ペプチドおよび同ペプチド抗体)

• The solid-state NMR spectroscopy as a technique for investigating membrane-binding proteins. In “Handbook of Modern Magnetic Resonance” (ed.: Webb G.):
  Kluwer Academic Publisher, Norwell 2005
• The solid-state NMR spectroscopy as a technique for investigating membrane-binding proteins. In “Handbook of Modern Magnetic Resonance” (ed.: Webb G.):
  Kluwer Academic Publisher, Norwell 2005
• Regulation of the nucleocytoplasmic shuttling of phosphoinositide-specific phospholipase C delta. In “Nuclear lipid metabolism and Signaling” (eds: Mansoli, F.A, Cocco, L., and Martelli, A.M.)
  Research Signpost, Kerala 2003
• Regulation of the nucleocytoplasmic shuttling of phosphoinositide-specific phospholipase C delta. In “Nuclear lipid metabolism and Signaling” (eds: Mansoli, F.A, Cocco, L., and Martelli, A.M.)
  Research Signpost, Kerala 2003
• ホスホリパーゼC.
  廣川ニューロサイエンス「神経の情報伝達」6巻「二次メッセンジャーと産生」 1997

ｍore...

• - 1982 The University of Tokyo
• - 1982 The University of Tokyo Graduate School, Division of Science
• - 1976 The University of Tokyo Faculty of Science
• - 1976 The University of Tokyo Faculty of Science

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高血圧関連疾患モデル学会 ,  アメリカ科学協会(AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE) ,  国際神経化学会(THE INTERNATIONAL SOCIETY FOR NEUROCHEMISTRY) ,  英国生化学会(THE BIOCHEMICAL SOCIETY) ,  日本生化学会 ,  International Society for Neurochemistry ,  AAAS ,  The Biochemical Society ,  Japanese Society for Cell Biology ,  Japanese Molecular Biological Society ,  Japanese Biochemical Society