Art

J-GLOBAL ID：200902131018330570   Reference number：02A0198252

The role of the 12-carboxylic acid group in the spontaneous autoxidation of dihydroartemisinic acid.

ジヒドロアルテミシニン酸の自然発生的な自動酸化における12-カルボン酸基の役割

Author (2)： SY L-K (Univ. Hong Kong, Hong Kong, CHN) ,  BROWN G D (Univ. Hong Kong, Hong Kong, CHN)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 58  Issue： 5  Page： 909-923  Publication year： Jan. 28, 2002 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： carboxylic acid ,...
Semi thesaurus term： bridged compound ,...

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JST classification (3)： Monoterpenes,sesquiterpenes  (CF10022A) ,  Oxidation,reduction  (CF02060T) ,  Plant biochemistry  (EH01050J)

Substance index (39)： Dihydroartemisinic acid ,  Artemisinin ,  Dihydroartemisinic acid hydroperoxide ,  (2R)-2-[(3S,4R)-2-(Hydroxymethylene)-3-(3-oxobutyl)-4-methylcyclohexyl]propionic acid ,  (2R)-2-[(1S,2R,3S,4R)-2-Formyl-2-hydroperoxy-3-(3-oxobutyl)-4-methylcyclohexyl]propionic acid ,  (αR,1R)-α,4β,7-Trimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene-1α-acetic acid methyl ester ,  (βR,1R)-β,4β,7-Trimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene-1α-ethanol ,  4-Amorphene ,  (αR,1S)-α,4β,7-Trimethyl-7β-hydroperoxy-1,2,3,4,4aβ,5,6,7-octahydronaphthalene-1α-acetic acid methyl ester ,  (βR,1S)-β,4β,7-Trimethyl-7β-hydroperoxy-1,2,3,4,4aβ,5,6,7-octahydronaphthalene-1α-ethanol ,  (1S)-1-Isopropyl-4β,7-dimethyl-7β-hydroperoxy-1,2,3,4,4aβ,5,6,7-octahydronaphthalene ,  (3R,3aS,6aS,10R,10aR,10bS)-3,10-Dimethyl-6-methylene-1,2,3,3a,4,5,6,6a,9,10,10a,10b-dodecahydro-7,8-dioxacyclohepta[de]naphthalene-9-one ,  (αR,1R)-α,4β-Dimethyl-7-(hydroperoxymethyl)-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene-1α-acetic acid ,  (αR,1R)-α,4β-Dimethyl-7-(hydroperoxymethyl)-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene-1α-acetic acid methyl ester ,  (βR,1R)-β,4β-Dimethyl-7-(hydroperoxymethyl)-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene-1α-ethanol ,  (1S)-1α-Isopropyl-4β-methyl-7-(hydroperoxymethyl)-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalene ,  (3R,6R,6aS,10aS)-3,6,9-Trimethyl-3,3a,4,5,6,6a,7,8-octahydro-2H-naphtho[8a,1-b]furan-2-one ,  (3R,6R,6aS,10aR)-3,6,9-Trimethyl-3,3a,4,5,6,6a,7,8-octahydro-2H-naphtho[8a,1-b]furan-2-one ,  (2R)-2-[(4R)-4β,7-Dimethyl-2,3,4,4aβ,5,6-hexahydronaphthalene-1-yl]-1-propanol ,  (3R,6R,6aS,9R,10R,10aR)-3,6,9-Trimethyl-9,10-epoxy-3,3a,4,5,6,6a,7,8,9,10-decahydro-2H-naphtho[8a,1-b]furan-2-one ,  (3R,3aβ,6aβ,10aα)-3α,6β,9-Trimethyl-9β,10bβ-epoxy-dodecahydropyrano[4,3,2-jk][2]benzoxepin ,  (2R)-2-[(5aS,6R)-3-Hydroxy-3,6-dimethyl-9a-formyloctahydro-3H-1,2-benzodioxepin-9-yl]propionic acid ,  (5aS,6R,9S)-3-Hydroxy-3,6-dimethyl-9-isopropyl-9a-formyloctahydro-3H-1,2-benzodioxepin ,  (1R,2S,3R,6S)-1-Hydroperoxy-2-(3-oxobutyl)-3-methyl-6-[(R)-1-(hydroxymethyl)ethyl]cyclohexanecarbaldehyde ,  (2R)-2-[(1S)-2-(Hydroxymethylene)-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (2R)-2-[(1S)-2-(Hydroxymethylene)-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]-1-propanol ,  (1S)-1β-Isopropyl-2-(hydroxymethylene)-3β-(3-oxobutyl)-4α-methylcyclohexane ,  (2R)-2-[(1R)-2α-Formyl-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (2R)-2-[(1R)-2β-Formyl-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (1R)-2β-(3-Oxobutyl)-3α-methyl-6β-isopropylcyclohexane-1β-carbaldehyde ,  (1S,4aβ,8aα)-4α,7β-Dimethyl-8α-(3-oxobutyl)octahydro-1H-2-benzopyran-1β-ol ,  (4R)-4α,7β-Dimethyl-8α-(3-oxobutyl)-3,4,4aβ,5,6,7,8,8a-octahydro-1H-2-benzopyran-1β-ol ,  (2S)-2β-(3-Oxobutyl)-3α-methyl-6β-[(1R)-1-methyl-2-(formyloxy)ethyl]cyclohexanone ,  2-[(1S)-2-Oxo-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (2S)-2β-(3-Oxobutyl)-3α-methyl-6β-isopropylcyclohexanone ,  (2R)-2-[(1S)-2-[[(2R)-2,5α-Dimethyl-8β-[1-(methoxycarbonyl)ethyl]-2,3,4,4aα,5,6,7,8-octahydronaphthalene-2α-yl]peroxy]-2-formyl-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (2S)-2-[(1S)-2-[[[(1R)-1-Formyl-2β-(3-oxobutyl)-3α-methyl-6β-[1-(methoxycarbonyl)ethyl]cyclohexane-1α-yl]oxy]methylene]-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (2S)-2-[(1S)-2-[[[(1S)-1-Formyl-2β-(3-oxobutyl)-3α-methyl-6β-[1-(methoxycarbonyl)ethyl]cyclohexane-1β-yl]oxy]methylene]-3β-(3-oxobutyl)-4α-methylcyclohexane-1β-yl]propionic acid methyl ester ,  (1S)-1β-Isopropyl-2-[[[(1R)-1-formyl-2β-(3-oxobutyl)-3α-methyl-6β-[1-(methoxycarbonyl)ethyl]cyclohexane-1α-yl]oxy]methylene]-3β-(3-oxobutyl)-4α-methylcyclohexane

Terms in the title (6)： ジヒドロアルテミシニン ,  酸 ,  自然発生 ,  自動酸化 ,  カルボン酸基 ,  役割