Art

J-GLOBAL ID：200902131045625914   Reference number：02A0650403

Pharmacological and clinical properties of didanosine (VIDEX), a nucleoside reverse transcriptase inhibitor.

核酸系逆転写酵素阻害薬ジダノシン(バイデックス)の薬理作用と臨床効果

Author (3)： OKIYAMA MASAHIKO (ブリストル) ,  KAWASHIMA HIROAKI (ブリストル) ,  FUKUNISHI SACHI (ブリストル)
Material： 日本薬理学雑誌  (日本薬理学会西南部会抄録)
Volume： 120  Issue： 2  Page： 115-122  Publication year： Aug. 01, 2002 
JST Material Number： G0740A  ISSN： 0015-5691  CODEN： NYKZA  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： *RNA-dependent DNA polymerase ,...

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JST classification (1)： Clinical application of antiviral drugs  (GW17050Z)

Substance index (1)： Didanosine

Reference (20)：

• 1) AIDS epidemic update: UNAID/WHO December, 2001
• 2) Mitsuya H and Broder S: Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleoside. Proc Natl Acad Sci USA 83, 1911-1915 (1986)
• 3) Mitsuya H and Broder S: Long term inhibition of human T-lymphotropic virus type-3/lymphadenopathy-associtated virus (Human Immunodeficiency Virus, HIV DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in-vitro.) Proc Natl Acad Sci USA 84, 2033-2039 (1987)
• 4) Perry CM and Noble S: Didanosine / An update review of its use in HIV infection. Drug 58, 1099-1135 (1999)
• 5) Perry CM and Balfour JA: Didanosine / An update on its antiviral activity, pharmacokinetics properties and therapeutic efficacy in the management on HIV disease. Drug 52, 928-962 (1996)

Terms in the title (4)： 核酸系逆転写酵素阻害薬 ,  ジダノシン ,  薬理作用 ,  臨床効果