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ArticleJ-GLOBAL ID:200902165196743090整理番号:01A0195128

A possible antimalarial action mode of qinghaosu (artemisinin) series compounds. Alkylation of reduced glutathione by C-centered primary radicals produced from antimalarial compound qinghaosu and 12-(2,4-dimethoxyphenyl)-12-deoxoqinghaosu.

一連のキンガオス(アルテミシニン)系化合物の可能な抗マラリア薬作用機序 抗マラリア薬化合物キンガオスおよび12‐(2,4‐ジメトキシフェニル)‐12‐デオキソキンガオスから生成されるC‐中心の第一ラジカルによる還元型グルタチオンのアルキル化

著者:WANG D‐Y(Shanghai Inst. Organic Chemistry, Chinese Acad. Sci., Shanghai, CHN)、WU Y‐L(Shanghai Inst. Organic Chemistry, Chinese Acad. Sci., Shanghai, CHN)
資料名:Chem Commun 号:22 ページ:2193-2194
発行年:2000年11月21日
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