Effects of orally administered olopatadine hydrochloride on the ocular allergic reaction in rats

TAMURA T; SATO H; MIKI I; SUZUKI K; OHMORI K; KARASAWA A

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J-GLOBAL ID：200902212435016226 Reference number：03A0445327

Effects of orally administered olopatadine hydrochloride on the ocular allergic reaction in rats

ラットの眼アレルギー反応に対する塩酸オロパタジン経口投与の効果

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Material：
Volume： 52 Issue： 2 Page： 77-83 Publication year： Jun. 2003
JST Material Number： W1027A ISSN： 1323-8930 Document type： Article
Article type：原著論文 Country of issue： Australia (AUS) Language： ENGLISH (EN)

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Basic research of histaminergic drugs and antihistaminergic drugs

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3. Nonaka H, Otaki S, Ohshima E et al. Unique binding pocket for KW-4679 in the histamine H₁ receptor. Eur. J. Pharmacol. 1998; 12: 111-117.
4. Sharif NA, Xu SX, Yanni JM. Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H₁-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis. J. Ocul. Pharmacol. Ther. 1996; 12: 401-407.
5. Ohmori K, Hayashi K, Kaise T et al. Pharmacological, pharmacokinetic and clinical properties of olopatadine hydrochloride, a new antiallergic drug. Jpn. J. Pharmacol. 2002; 88: 379-397.

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