Art

J-GLOBAL ID：200902212469181978   Reference number：08A1168824

新規チロシンキナーゼ阻害薬ダサチニブ

Author (2)： ONISHI SHINTARO (ブリストル・マイヤーズ) ,  SERIU TAKU (ブリストル・マイヤーズ)
Material： 月刊細胞  (細胞)
Volume： 40  Issue： 14  Page： 620-627  Publication year： Dec. 20, 2008 
JST Material Number： F0692A  ISSN： 1346-7557  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *antitumor drug ,...
Semi thesaurus term： Leukemia, Lymphocytic, Acute ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Dasatinib

Reference (72)：

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• Fanta S, et al.: Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr Abl-negative cells. Oncogene.27(31): 4380-4384, 2008.
• McWhirter JR, et al.: A Coiled-Coil Oligomerization Domain of Bcr Is Essential for the Transforming Function of Bcr-Abl Oncoproteins. Molecular and Cellular Biol.13(12): 7587-7595, 1993.
• Zhao X. et al.: Structure of the Bcr-Abl oncoprotein oligomerization domain. Nature Structural Biology.9: 117-120, 2002.
• Taylor CM, et al.: Orientation and Oligomerization Specificity of the Bcr Coiled-Coil Oligomerization Domain. Biochemistry 44: 16246-16256, 2005.

Terms in the title (2)： チロシンキナーゼ阻害薬 ,  ダサチニブ