Art

J-GLOBAL ID：200902212508113586   Reference number：06A0958933

Emodin inhibits TNF α-induced MMP-1 expression through suppression of activator protein-1 (AP-1)

エモジンはアクチベータ蛋白質-1(AP-1)の抑制によりTNFα誘発MMP-1発現を阻害する

Author (12)： LEE Jongsung (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR) ,  LEE Jongsung (Natural Products Res. Inst., Coll. of Pharmacy, Seoul National Univ., Seoul, KOR) ,  JUNG Eunsun (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR) ,  LEE Jiyoung (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR) ,  HUH Sungran (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR) ,  HWANG Cheng-hwan (Cosmetics and Personal Care Res. Institute, Amorepacific corporation/R and D center 314-1, Bora-dong, Giheung-gu ...) ,  LEE Hwa-young (Cosmetics and Personal Care Res. Institute, Amorepacific corporation/R and D center 314-1, Bora-dong, Giheung-gu ...) ,  KIM Eun-jung (Cosmetics and Personal Care Res. Institute, Amorepacific corporation/R and D center 314-1, Bora-dong, Giheung-gu ...) ,  CHEON Ji-min (Cosmetics and Personal Care Res. Institute, Amorepacific corporation/R and D center 314-1, Bora-dong, Giheung-gu ...) ,  HYUN Chang Gu (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR) ,  KIM Yeong Shik (Natural Products Res. Inst., Coll. of Pharmacy, Seoul National Univ., Seoul, KOR) ,  PARK Deokhoon (Biospectrum Life Sci. Inst., Gunpo City, Gyunggi Do, KOR)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 79  Issue： 26  Page： 2480-2485  Publication year： Nov. 25, 2006 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： transcription factor ,...
Semi thesaurus term： *AP-1 ,...

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JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (1)： Emodin

Terms in the title (9)： エモジン ,  アクチベータ ,  蛋白質 ,  AP-1 ,  TNFα ,  誘発 ,  MMP-1 ,  発現 ,  阻害