Art

J-GLOBAL ID：200902212508659295   Reference number：04A0789841

Studies of the Effects of Antifungal Cationic Derivatives of Amphotericin B on Human Erythrocytes

ヒト赤血球に及ぼすアンホテリシンBの抗真菌カチオン誘導体の作用の研究

Author (5)： SLISZ M (Gdansk Univ. Technol., Gdansk, POL) ,  CYBULSKA B (Gdansk Univ. Technol., Gdansk, POL) ,  MAZERSKI J (Gdansk Univ. Technol., Gdansk, POL) ,  GRZYBOWSKA J (Gdansk Univ. Technol., Gdansk, POL) ,  BOROWSKI E (Gdansk Univ. Technol., Gdansk, POL)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 57  Issue： 10  Page： 669-678  Publication year： Oct. 25, 2004 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antifungal drug ,...
Semi thesaurus term： MIC(concentration) ,...

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JST classification (2)： Basic research of antifungal drugs  (GW17060K) ,  Erythrocytes  (EJ03020W)

Substance index (10)： Amphotericin B ,  16-Decarboxy-16-[3-(dimethylamino)propylcarbamoyl]amphotericin B ,  16-[(4-Methylpiperazino)carbonyl]-16-decarboxyamphotericin B ,  16-[[2-(2-Pyridyl)ethyl]aminocarbonyl]-16-decarboxyamphotericin B ,  16-[(2-Morpholinoethyl)aminocarbonyl]-16-decarboxyamphotericin B ,  16-[(4-Methylpiperazino)aminocarbonyl]-16-decarboxyamphotericin B ,  3′-[1-[3-(Dimethylamino)propyl]-2,5-dioxopyrrolidine-3-ylamino]-3′-deaminoamphotericin B methyl ,  Methamphocin ,  3′-(2,5-Diaminopentanoylamino)-3′-deaminoamphotericin B methyl ,  3′-(2,5-Diaminopentanoylamino)-16-[[3-(dimethylamino)propyl]aminocarbonyl]-3′-deamino-16-decarboxyamphotericin B

Reference (31)：

• 1) GALLIS, H. A.; R. H. DREW & W. W. PICKARD: Amphotericin B: 30 years of clinical experience. Rev. Infect. Dis. 12: 308-329, 1990
• 2) BOLARD, J.: How do the polyene macrolide antibiotics affect the cellular membrane properties. Biochim. Biophys. Acta 864: 257-304, 1986
• 3) BRAJTBURG, J.; W. G. POWDERLY, G. S. KOBAYASHI &. G. MEDOFF: Amphotericin B: Current understanding of mechanisms of action. Antimicrob. Agents Chemother. 34(2): 183-188, 1990
• 4) HARTSEL, S. & J. BOLARD: Amphotericin B: new life for an old drug. TiPS 17: 445-449, 1996
• 5) ZOTCHEV, S. B.: Polyene macrolide antibiotics and their applications in human therapy. Curr. Med. Chem. 10: 211-223, 2003

Terms in the title (6)： ヒト ,  赤血球 ,  アンホテリシンB ,  真菌 ,  チオン誘導体 ,  研究