Chamoto Kenji

チヤモトケンジ | Chamoto Kenji

Affiliation and department：
Homepage URL (1)： http://www2.mfour.med.kyoto-u.ac.jp/pd-1_project.html

Research field (3)： Pathobiochemistry , Tumor diagnostics and therapeutics , Immunology

Research keywords (3)：がん免疫 , Autoimmunity , Metabolism

Research theme for competitive and other funds (10)：

2021 - 2025 Novel diagnostic and therapeutic strategies for ovarian cancer by investigation of cancer and host diversity
2021 - 2024 Investigation of B-cell immunity against gynecological cancer and new strategies for diagnosis and treatment
2021 - 2024 Impact of circulating exhausted T cells with different stages on PD-1 blockade caner immunotherapy
2019 - 2024 Research and development about helium and proton hybrid system with proton CT and Immuno-radiotherapy
2018 - 2021 Investigation of immune-suppressive dynamism and exploratory research for new treatment strategy for gynecologic cancer

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Papers (102)：

Hidetoshi Hayashi, Kenji Chamoto, Ryusuke Hatae, Takashi Kurosaki, Yosuke Togashi, Kazuya Fukuoka, Megumi Goto, Yasutaka Chiba, Shuta Tomida, Takayo Ota, et al. Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade. Journal of Clinical Investigation. 2024. 134. 7
Junko Tanizaki, Hiroaki Kuroda, Toshihide Yokoyama, Makoto Takahama, Hiroyasu Shoda, Atsushi Nakamura, Yoshitaka Kitamura, Nobuaki Mamesaya, Yoshihisa Kadota, Kenji Sawa, et al. Lack of Association of Plasma Levels of Soluble PD-1, PD-L1, and CTLA-4 with Survival for Stage II to IIIA Non-Small Cell Lung Cancer after Complete Resection and Adjuvant Chemotherapy. JTO Clinical and Research Reports. 2023. 100590-100590
Kenji Chamoto, Baihao Zhang, Masaki Tajima, Tasuku Honjo, Sidonia Fagarasan. Spermidine - an old molecule with a new age-defying immune function. Trends in Cell Biology. 2023
Insights from 30-year journey: function, regulation and therapeutic modulation of PD1. Nat Rev Immnol. 2023. 23. 10. 682-695
Hisato Kawakami, Yu Sunakawa, Eisuke Inoue, Ryo Matoba, Kenta Noda, Toshiyuki Sato, Chihiro Suminaka, Mami Yamaki, Yasuhiro Sakamoto, Ryohei Kawabata, et al. Soluble programmed cell death ligand 1 predicts prognosis for gastric cancer patients treated with nivolumab: Blood-based biomarker analysis for the DELIVER trial. European Journal of Cancer. 2023. 184. 10-20

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MISC (11)：

谷崎潤子, 黒田浩章, 横山俊秀, 高濱誠, 庄田浩康, 中村敦, 北村嘉隆, 豆鞘伸昭, 門田嘉久, 光岡茂樹, et al. 切除可能非小細胞肺癌II-IIIA期における可溶性免疫因子の検討(WJOG12319LTR). 肺癌. 2022. 62. 6. 594-594
宮島倫生, 章白浩, 章白浩, 杉浦悠毅, 園村和弘, グェッリーニマッテオ, 茶本健司, 古川貴久, 石濱泰, 松田文彦, et al. T細胞活性化に起因する全身性のメタボロームシフトを介した情動行動変化. がんと代謝研究会プログラム&抄録集. 2019. 7th
波多江龍亮, 茶本健司. 序 : PD-1阻害がん免疫治療の現状と今後の展望 (特集免疫チェックポイントとがん免疫治療). 血液フロンティア. 2017. 27. 11. 1505-1510
Immunotherapy using artificial antigen-presenting cells. 2013. 244. 9. 831-836
大栗敬幸, 野口大輔, 小林稔, 増子和尚, 大竹淳矢, 脇田大功, 茶本健司, 富樫裕二, 北村秀光, 西村孝司. 新規Survivinヘルパーペプチドの同定と免疫不全マウスを用いたSurvivin特異的Th1細胞による抗腫瘍効果の検討(Identification of novel helper epitopes of Survivin and antitumor effects of human Th1 cells in immunodeficient mice). 日本癌学会総会記事. 2009. 68回. 287-287

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Patents (7)：

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Books (52)：

もっとよくわかる!腫瘍免疫学第3章がんの進展、項目2腫瘍微小環境の代謝制御、項目3腸内細菌叢によるがん免疫応答の調整
羊土社 2023 ISBN:9784758122122
T細胞老化と炎症のつながり
実験医学 41 2023
スペルミジンによる脂肪酸酸化の調節と老化T細胞の抗腫瘍効果の回復
医学のあゆみ 287 2023
スペルミジンによる老化制御機構-全身性エリテマトーデスにおける免疫老化とポリアミン代謝-
臨床免疫・アレルギー科 79 2023
スペルミジンは脂肪酸酸化酵素に結合し老化による腫瘍免疫の低下を回復させる
実験医学 41 2023

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Lectures and oral presentations (149)：

ポリアミンによる免疫老化抑制とがん免疫治療、
(第46回日本分子生物学会 2023)
ポリアミン代謝によるT細胞老化の機序解明
(第37回日本エイズ学会学術集会・総会、シンポジウム8 2023)
Spermidine activates fatty acid oxidation and improves antitumor immunity in mice
(2023)
ポリアミン代謝機構とがん免疫療法
(第96回日本生化学大会 2023)
がん免疫の30年の軌跡と新たな挑戦
(第61回日本癌治療学会学術集会 2023)

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Works (4)：

Education (6)：

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Professional career (1)：

Work history (15)：

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Committee career (3)：

Awards (14)：

2021 - Public Interest Incorporated Foundation Kiyoko Goto and Paul Bourdarie Cancer Foundation Kiyoko and Paul Bourdarie-Goto Scientific Prize-Special Award Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy.
2017 - 日本癌学会奨励賞
2014 - Ontario Cancer Institute/Princess Margaret Cancer Center UHN ORT Conference Travel Award
2014 - The American Association of Immunologists (AAI) Annual Meeting AAI Trainee Abstract Award
2013 - 日本分子生物学会第36回 travel award

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Association Membership(s) (5)：

癌学会 , 日本がん免疫学会 , 免疫学会 , 日本臨床腫瘍学会 , 分子生物学会

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