Rchr
J-GLOBAL ID:200901019240740452   Update date: Mar. 20, 2024

Sohtome Yoshihiro

ソウトメ ヨシヒロ | Sohtome Yoshihiro
Affiliation and department:
Job title: Assistant Professor
Other affiliations (1):
Homepage URL  (1): http://soc.riken.jp
Research field  (3): Synthetic organic chemistry ,  Chemical biology ,  Biochemistry
Research keywords  (7): 有機合成化学 ,  不斉触媒 ,  化学生物学 ,  Computational chemistry ,  Chemical Biology ,  Asymmetric Catalysis ,  Organic Chemistry
Research theme for competitive and other funds  (15):
  • 2022 - 2026 Dynamic chemical control of protein methylation
  • 2022 - 2025 Synergistic effects induced by neo-PTMs
  • 2022 - 2025 In-cell chemical network driven by neo-PTMs
  • 2018 - 2022 Seed compounds exploratory empowered by catalysis
  • 2017 - 2022 Synthetic strategy for chemical methylome analyses
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Papers (54):
  • Yoshihiro Sohtome, Mikiko Sodeoka. Catalytic oxidative carbon-carbon bond-formations of benzene-1,2-diols. Pure and Applied Chemistry. 2023
  • Tadahiro Shimazu, Rei Yoshimoto, Kaoru Kotoshiba, Takehiro Suzuki, Shogo Matoba, Michiko Hirose, Mai Akakabe, Yoshihiro Sohtome, Mikiko Sodeoka, Atsuo Ogura, et al. Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism. Genes & Development. 2023. 37. 724-742
  • Yoshihiro Sohtome, Shinsuke Komagawa, Ayako Nakamura, Daisuke Hashizume, Sylvain Lectard, Mai Akakabe, Yoshitaka Hamashima, Masanobu Uchiyama, Mikiko Sodeoka. Experimental and Computational Investigation of Facial Selectivity Switching in Nickel-Diamine-Acetate-Catalyzed Michael Reactions. The Journal of Organic Chemistry. 2023. 88. 7764-7773
  • Masumi Sugawara, Miki Sawamura, Mai Akakabe, Boobalan Ramadoss, Yoshihiro Sohtome, Mikiko Sodeoka. Pd-catalyzed Aerobic Cross-Dehydrogenative Coupling of Catechols with 2-Oxindoles and Benzofuranones: Reactivity Difference Between Monomer and Dimer. Chemistry - An Asian Journal. 2022
  • Yoshihiro Sohtome, Mikiko Sodeoka. Theoretical Insights into the Substrate-Dependent Diastereodivergence in (3 + 2) Cycloaddition of α-Keto Ester Enolates with Nitrones. Chemical and Pharmaceutical Bulletin. 2022. 70. 9. 616-623
more...
MISC (34):
  • 五月女宜裕, 菅原真純, 大西理華子, 澤村美紀, 赤壁麻依, 袖岡幹子. 持続性ラジカルとカテコールとの酸化的クロスカップリングに関する機構解析. 有機合成化学協会関東支部シンポジウム: 第84回東京農工大シンポジウム講演要旨集. 2023
  • 五月女 宜裕. メチル化基質探索のための人工的化学修飾の導入. 日本薬学会第143回要旨集. 2023
  • Yoshihiro Sohtome, Masumi Sugawara, Miki Sawamura, Mai Akakabe, Boobalan Ramadoss, Mikiko Sodeoka. Aerobic Cross-Dehydrogenative Coupling of Catechols with Persistent Radicals. 2023
  • Yoshihiro Sohtome, Tetsuya Ezawa, Daisuke Hashizume, Masaya Adachi, Mai Akakabe, Hiroyuki Koshino, Mikiko Sodeoka. Dynamic catalytic diastereoconvergent (3+2) cycloaddition with alpha-keto ester enolates. 2022
  • Yoshihiro SOHTOME. Dynamic Diastereoconvergent Catalysis. 2021. 74. 860-860
more...
Books (6):
  • Designed Molecular Space in Material Science and Catalysis
    Springer 2018
  • 実験医学別冊 エピジェネティクス実験スタンダード: もう悩まない!ゲノム機能制御の読み解き方
    羊土社 2017
  • 化学の要点シリーズ18 基礎から学ぶケミカルバイオロジー
    共立出版 2016
  • Science of Synthesis Reference Library, Asymmetric Organocatalysis 2; Brønsted Base and Acid Catalysts, and additional Topics
    2012
  • Comprehensive Chirality
    Elsevier 2012
more...
Lectures and oral presentations  (46):
  • 遷移金属錯体触媒を用いる動的不斉反応
    (日本化学会第104春季年会 (2024) 特別企画 2024)
  • 境界領域への挑戦から探る動的反応化学
    (立命館大学生命科学部: 超分子創製化学セミナー (第92回) 2024)
  • メチル化基質探索のためのneo-PTMsプローブ
    (第96回日本生化学会大会 2023)
  • SOMO-HOMO level inversion
    (2023)
  • 境界領域への挑戦から探る動的反応化学
    (千葉大学薬学部講演会 2023)
more...
Education (3):
  • 2003 - 2006 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
  • 2001 - 2003 The University of Tokyo Graduate School of Agricultural and Life Sciences
  • 1997 - 2001 Keio University Faculty of Science and Technology Department of Chemistry
Professional career (1):
  • 博士 (薬学) (東京大学)
Work history (12):
  • 2018/04 - 現在 国立研究開発法人理化学研究所 袖岡有機合成化学研究室 専任研究員
  • 2021/04 - 2021/09 Saitama University
  • 2020/04 - 2021/03 Kyoto University Institute for Chemical Research
  • 2019/04 - 2019/09 Saitama University
  • 2018/09 - 2018/09 Rikkyo University
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Committee career (8):
  • 2019/06 - 現在 文部科学省 科学技術専門家ネットワーク・専門調査員
  • 2014 - 現在 日本化学会新領域研究グループ 「精密物質変換のための分子空間化学」
  • 2018/02 - 2020/02 有機合成化学協会 編集委員
  • 2017 - 理化学研究所 化学安全委員会委員
  • 2017 - 有機合成化学協会 YUGOKAFe NExT 第一回世話人
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Awards (11):
  • 2023/12 - ICCEOCA-16: The 16th International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award from Taiwan Ni(II)-catalyzed Diastereoconvergent (3 + 2) Cycloaddition of alpha-Ketoester Enolates
  • 2022/03 - RIKEN RIKEN BAIHO Award Development of Dynamic Catalytic Asymmetric Diastereoconvergent Reactions
  • 2018/06 - JSPS program, “Precisely Designed Catalysts with Customized Scaffolding” Lectureship Award 2018 "Controlling Chiral Environments Constructed by Molecular Catalysis and Enzymes"
  • 2016/01 - Georg Thieme Verlag, Thieme Chemistry Journals Award
  • 2015/10 - MSD Life Science Foundation, Banyu Chemist Award "Dynamically Tunable Asymmetric Organocatalysis Controlled by Conformationally Flexible Organocatalysts"
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Association Membership(s) (7):
日本エピジェネティクス研究会 ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  KINKI CHEMICAL SOCIETY, JAPAN ,  アメリカ化学会 ,  有機合成化学協会 ,  日本薬学会 ,  日本化学会
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