Noriko Yoshimoto

Affiliation and department：
Job title：准教授

Research field (1)： Applied biofunctional and bioprocess engineering

Research theme for competitive and other funds (6)：

2021 - 2024 抗体-薬物複合体を固液界面で立体選択的に合成・高純度化するクロマトグラフィー
2018 - 2021 Characterization and purification of oligonucleotides-polymer conjugates with higher-order structure
2018 - 2020 Development of sequential and reaction process with monolithic column module for small antibodies PEGylation
2016 - 2018 Surface modification of monolithic pore for solid phaseprotein PEGylation based on its mass transfer
2014 - 2016 Development of separation process for PEGylated positional isoforms based on the intrinsic interaction with specific structure on the solid-liquid interface

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Papers (60)：

Noriko Yoshimoto. Continuous Protein Modification and Separation Process with Chromatography. Japan Journal of Food Engineering. 2022. 23. 1. 1-12
Hidenori Inaba, Kosuke Wakabayashi, Ikuo Tsujimoto, Noriko Yoshimoto, Shuichi Yamamoto. Measurement of High Protein Concentrations by Optical Rotation: A Case Study for Monitoring of Monoclonal Antibody Drug Downstream Processes. Current Protein and Peptide Science. 2021. 22. 12. 898-904
Chyi Shin Chen, Fuminori Konoike, Noriko Yoshimoto, Shuichi Yamamoto. A regressive approach to the design of continuous capture process with multi-column chromatography for monoclonal antibodies. Journal of Chromatography A. 2021. 1658
Joao Carlos Simoes-Cardoso, Nanako Hoshino, Yusuke Yoshimura, Chyi-Shin Chen, Cristina Dias-Cabral, Noriko Yoshimoto, Shuichi Yamamoto. Correlation between protein desorption behavior and its adsorption enthalpy change in polymer grafted anion exchange chromatography. Colloids and surfaces. B, Biointerfaces. 2021. 205. 111853-111853
Shigenori Ota, Yuko Yui, Tsutomu Sato, Noriko Yoshimoto, Shuichi Yamamoto. Rapid Purification of Immunoglobulin G Using a Protein A-immobilized Monolithic Spin Column with Hydrophilic Polymers. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2021. 37. 7. 985-990

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MISC (11)：

Takashi Kaminagayoshi, Noriko Yoshimoto, Shuichi Yamamoto. Statistical evaluation of cleaning processes in food manufacturing facilities. Japan Journal of Food Engineering. 2021. 22. 2. 47-51
Shuichi Yamamoto, Noriko Yoshimoto, Yu Isakari, Ales Podgornik. Optimization of monomer separation processes by electrostatic-interaction chromatography. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2015. 249
S. Ohshima, N. Yoshimoto, S. Yamamoto. Molecular and pore diffusion coefficients of DNAs and modified proteins for process chromatography. Liaison Functions 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. 2013. 73
S. Ohshima, N. Yoshimoto, S. Yamamoto. Molecular and pore diffusion coefficients of dnas and modified proteins for process chromatography. Separations Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. 2013. 243
Shuichi Yamamoto, Yuki Suehiro, Hiroyuki Nagaoka, Noriko Yoshimoto, Kazunobu Minakuchi. Simple and fast methods for predicting the dynamic binding capacity by using 96-well format micro-plates and small chromatography columns. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 243

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Lectures and oral presentations (4)：

DNAおよびタンパク質のイオン交換クロマトグラフィーにおける保持に対するPEGの影響
(化学工学会山口大会講演要旨集 2007)
タンパク質クロマトグラフィーにおける圧力損失とカラム性能の関係
(化学工学会山口大会講演要旨集 2007)
イオン交換モノリスディスクを装着した96wellマイクロプレートを用いたハイスループットタンパク質分離プロセスの設計
(日本生物工学会大会講演要旨集 2007)
ポリフェノールのクロマト分離プロセス効率化方法の開発
(化学工学会研究発表講演要旨集 2007)

Work history (3)：

- 現在山口大学大学院創成科学研究科准教授
2010/05/18 - 2016/04/11 YAMAGUCHI UNIVERSITY Graduate School of Medicine(Engineering) Assistant Professor
2010/02/24 - 2010/05/17 YAMAGUCHI UNIVERSITY Graduate School of Medicine(Engineering)

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