2018 - 2021 Characterization and purification of oligonucleotides-polymer conjugates with higher-order structure
2018 - 2020 Development of sequential and reaction process with monolithic column module for small antibodies PEGylation
2016 - 2018 Surface modification of monolithic pore for solid phaseprotein PEGylation based on its mass transfer
2014 - 2016 Development of separation process for PEGylated positional isoforms based on the intrinsic interaction with specific structure on the solid-liquid interface
2003 - 2004 刺激応答性分子集合体を利用した生体機能模倣材料の調製とその応用
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Papers (60):
Noriko Yoshimoto. Continuous Protein Modification and Separation Process with Chromatography. Japan Journal of Food Engineering. 2022. 23. 1. 1-12
Hidenori Inaba, Kosuke Wakabayashi, Ikuo Tsujimoto, Noriko Yoshimoto, Shuichi Yamamoto. Measurement of High Protein Concentrations by Optical Rotation: A Case Study for Monitoring of Monoclonal Antibody Drug Downstream Processes. Current Protein and Peptide Science. 2021. 22. 12. 898-904
Chyi Shin Chen, Fuminori Konoike, Noriko Yoshimoto, Shuichi Yamamoto. A regressive approach to the design of continuous capture process with multi-column chromatography for monoclonal antibodies. Journal of Chromatography A. 2021. 1658
Joao Carlos Simoes-Cardoso, Nanako Hoshino, Yusuke Yoshimura, Chyi-Shin Chen, Cristina Dias-Cabral, Noriko Yoshimoto, Shuichi Yamamoto. Correlation between protein desorption behavior and its adsorption enthalpy change in polymer grafted anion exchange chromatography. Colloids and surfaces. B, Biointerfaces. 2021. 205. 111853-111853
Shigenori Ota, Yuko Yui, Tsutomu Sato, Noriko Yoshimoto, Shuichi Yamamoto. Rapid Purification of Immunoglobulin G Using a Protein A-immobilized Monolithic Spin Column with Hydrophilic Polymers. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2021. 37. 7. 985-990
Takashi Kaminagayoshi, Noriko Yoshimoto, Shuichi Yamamoto. Statistical evaluation of cleaning processes in food manufacturing facilities. Japan Journal of Food Engineering. 2021. 22. 2. 47-51
Shuichi Yamamoto, Noriko Yoshimoto, Yu Isakari, Ales Podgornik. Optimization of monomer separation processes by electrostatic-interaction chromatography. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2015. 249
Shuichi Yamamoto, Yuki Suehiro, Hiroyuki Nagaoka, Noriko Yoshimoto, Kazunobu Minakuchi. Simple and fast methods for predicting the dynamic binding capacity by using 96-well format micro-plates and small chromatography columns. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 243