Akira Ono

オノアキラ | Akira Ono

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://apchem2.kanagawa-u.ac.jp/onolab/index.html

Research field (7)： Nanostructure chemistry , Molecular biochemistry , Nanobioscience , Pharmaceuticals - chemistry and drug development , Clinical pharmacy , Functional solid-state chemistry , Biochemistry

Research keywords (9)： Hg(II) ion sensor , nucleic acid medicine , 金属含有DNAワイヤー , 水銀イオンセンサー , 核酸医薬 , ナノバイオサイエンス , 医薬品化学 , Nano bioscience , Medicinal chemistry

Research theme for competitive and other funds (20)：

2021 - 2025 Nucleic Acid-Metal Complexes: Preparation, structure analysis, characterization of metal-DNA wires and metal nanocluster-DNA complexes.
2019 - 2021 核酸構造上に構築された螺旋状金属イオン集積体のヘリシティー制御と単分子物性
2017 - 2021 Synthesis and characterization of metallo-DNA nanowire with infinite, uninterrupted one-dimensional metal ions array
2012 - 2016 Structural probing of RNA molecules with in-cell NMR
2012 - 2015 DNAを利用する重金属イオン除去膜、導電性ワイヤーの開発計画-構造、物性、応用

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Papers (119)：

Takahiro Atsugi, Akira Ono, Miho Tasaka, Natsumi Eguchi, Shoji Fujiwara, Jiro Kondo. A Novel Ag(I)-DNA Rod Comprising a One-Dimensional Array of 11 Silver Ions within a Double Helical Structure. Angewandte Chemie International Edition. 2022
Hisao Saneyoshi, Kodai Nakamura, Kazuma Terasawa, Akira Ono. A Bioreductive Protecting Group for RNA Synthesis. Current protocols. 2021. 1. 9. e240
Hisao Saneyoshi, Akira Ono. Design and Synthesis of Protecting Groups for Pro-oligo Type Nucleic Acid-based Drugs. Journal of Synthetic Organic Chemistry, Japan. 2020. 78. 9. 886-893
Hisao Saneyoshi, Kodai Nakamura, Kazuma Terasawa, Akira Ono. Development of Bioreduction Labile Protecting Groups for the 2′-Hydroxyl Group of RNA. Organic Letters. 2020. 22. 15. 6006-6009
Ryo Yamada, Issei Nomura, Yuki Yamaguchi, Yosuke Matsuda, Yoshikazu Hattori, Hirokazu Tada, Akira Ono, Yoshiyuki Tanaka. Electrical conductance measurement of HgII-mediated DNA duplex in buffered aqueous solution. Nucleosides, Nucleotides & Nucleic Acids. 2020. 39. 8. 1083-1087

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MISC (31)：

Akira Ono, Itaru Okamoto, Hideo Urata, Hidetake Torigoe, Hisao Saneyoshi, Jiro Kondo, Yoshiyuki Tanaka. Syntheses of DNA duplexes containing metal ion mediated base pairs. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S716-S716
Yoshiyuki Tanaka, Itaru Okamoto, Kyoko Furuita, Jakub Sebera, Jiro Kondo, Hidetaka Torigoe, Hidehito Urata, Takenori Dairaku, Akira Ono, Chojiro Kojima, et al. NMR spectroscopic studies on metallo-base-pair in DNA duplex. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S732-S733
Akira Ono, Hidetaka Torigoe, Yoshiyuki Tanaka, Itaru Okamoto. Binding of metal ions by pyrimidine base pairs in DNA duplexes. CHEMICAL SOCIETY REVIEWS. 2011. 40. 12. 5855-5866
Itaru Okamoto, Kenji Iwamoto, Yuko Watanabe, Yoko Miyake, Akira Ono. Metal-Ion Selectivity of Chemically Modified Uracil Pairs in DNA Duplexes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2009. 48. 9. 1648-1651
Itaru Okamoto, Kenji Iwamoto, Yuko Watanabe, Yoko Miyake, Akira Ono. Metal-Ion Selectivity of Chemically Modified Uracil Pairs in DNA Duplexes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2009. 48. 9. 1648-1651

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Books (1)：

“DDS先端技術の製剤への応用開発. 3章プロドラッグ化/アンテドラッグ化によるDDSの開発 4節核酸医薬のプロドラッグ化”、
技術情報協会 2017

Education (3)：

1983 - 1985 北海道大学大学院薬学研究科製薬化学専攻
1981 - 1983 北海道大学大学院薬学研究科製薬化学専攻
1976 - 1981 北海道大学薬学部製薬化学科

Work history (6)：

2005 - 2006 Kanagawa University Faculty of Engineering
2006 - - 神奈川大学工学部教授
1998/04 - 2005/03 Associate Professor
1993/04 - 1998/03 Associate Professor
1986/11 - 1993/03 Research Assistant

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Association Membership(s) (6)：

ナノ学会 , 分析化学会 , 高分子学会 , 日本薬学会 , 日本化学会 , 日本核酸医薬学会

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