Ohtani Kiyoshi

オオタニキヨシ | Ohtani Kiyoshi

Affiliation and department：
Job title： Professor

Research field (4)： Tumor biology , Virology , Cell biology , Molecular biology

Research keywords (9)： RB/E2F , がん化抑制機構 , がん化機構 , ウイルス発癌 , 転写制御 , 細胞周期制御 , Viral Oncogenesis , Transcriptional Regulation , Cell Cycle Regulation

Research theme for competitive and other funds (6)：

HTLV-Iによる発癌機序
E2Fの新しい標的遺伝子の同定
細胞周期制御
Oncogenesis by HTLV-I
Functional analyses of new E2F target genes and distinct transcriptional regulation mediated by E2F

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Papers (32)：

Yaxuan Zhou, Rinka Nakajima, Mashiro Shirasawa, Mariana Fikriyanti, Lin Zhao, Ritsuko Iwanaga, Andrew P Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani. Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression. Biology. 2023. 12. 12
Rinka Nakajima, Reika Deguchi, Hideyuki Komori, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Arlene Angelina, Yasuko Goto, Fumiya Tohjo, Kengo Nakahashi, et al. The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F. Biochemical and biophysical research communications. 2023. 663. 154-162
Rinka Nakajima, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Ayato Uchida, Hikaru Murakawa, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P Bradford, Keigo Araki, et al. Deregulated E2F Activity as a Cancer-Cell Specific Therapeutic Tool. Genes. 2023. 14. 2
Xi Zhang, Mingming Zhang, Sijun Huang, Kiyoshi Ohtani, Li Xu, Yi Guo. Engineered Polymeric Nanovector for Intracellular Peptide Delivery in Antitumor Therapy. International journal of nanomedicine. 2023. 18. 5343-5363
Keigo Araki, Keiko Kawauchi, Wataru Sugimoto, Daisuke Tsuda, Hiroya Oda, Ryosuke Yoshida, Kiyoshi Ohtani. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Communications biology. 2019. 2. 3-3

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MISC (31)：

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Professional career (1)：

Work history (4)：

Association Membership(s) (2)：

分子生物学会 , 癌学会

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