Rchr
J-GLOBAL ID：200901090550249860   Update date: Oct. 03, 2023

Yamamoto Takeshi

ヤマモト タケシ | Yamamoto Takeshi
Affiliation and department：
Kanazawa Gakuin University

About Kanazawa Gakuin University


Research field  (5)： Food sciences ,  Immunology ,  Pharmacology ,  Physiology ,  Internal medicine - General
Research keywords  (8)： 和漢薬 ,  腸管粘膜免疫 ,  食物アレルギー ,  漢方薬 ,  腸管吸収 ,  ビタミンに関する研究 ,  intestinal absorption ,  reasearch of vitamin
Research theme for competitive and other funds  (9)：
  • 2019 - 2023 漢方薬併用経口免疫療法による食物抗原耐性獲得の検討と治療評価血液マーカーの探索
  • 2016 - 2019 Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy
  • 2013 - 2016 Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colon
  • 2010 - 2012 The effect of kakkonto in allergic immune response mediated by dendritic cells on intestinal mucosal immune system
  • 2009 - 2011 Immunological tolerance induced by Kampo medicine kakkonto through the regulation of helper T cell differentiation in the mucosal immune system of the intestine.
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Papers (40)：
  • Takeshi YAMAMOTO, Yosuke KATSUKI, Yuya KANAUCHI, Shusaku HAYASHI, Makoto KADOWAKI. Allergic inflammation disrupts epithelial electrogenic electrolyte transport through cholinergic regulation in the mouse colon. Biomedical Research. 2023. 44. 1. 31-40
  • Yuya Kanauchi, Takeshi Yamamoto, Minako Yoshida, Yue Zhang, Jaemin Lee, Shusaku Hayashi, Makoto Kadowaki. Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells. Scientific Reports. 2022. 12. 1
  • Makoto Kadowaki, Takeshi Yamamoto, Shusaku Hayashi. Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells. Allergology International. 2022. 71. 3. 278-287
  • Yue Zhang, Takeshi Yamamoto, Shusaku Hayashi, Makoto Kadowaki. Suppression of plasmacytoid dendritic cell migration to colonic isolated lymphoid follicles abrogates the development of colitis. Biomedicine & Pharmacotherapy. 2021. 141. 111881-111881
  • Tomoe Yashiro, Hanako Ogata, Syed Faisal Zaidi, Jaemin Lee, Shusaku Hayashi, Takeshi Yamamoto, Makoto Kadowaki. Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice. Cells. 2021. 10. 7. 1586-1586
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MISC (23)：
  • 長田 夕佳, 山本 武, 門脇 真. 生姜によるレチノイン酸合成酵素の発現誘導 ヒト腸管上皮培養細胞Caco-2を用いた検討. 日本栄養・食糧学会大会講演要旨集. 2019. 73回. 291-291
  • 長田夕佳, 山本武, 門脇真. 経口免疫療法モデルマウスを用いた葛根湯併用療法の寛解維持効果の検討. アレルギー. 2018. 67. 4/5. 644-644
  • Yuka Nagata, Takeshi Yamamoto, Makoto Kadowaki. Long-Term Effect of Combined Therapy of Oral Immunotherapy and Japanese Traditional Medicine Kakkonto on Food Allergy Mice. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018. 141. 2. AB242-AB242
  • Hanako Ogata, Makoto Kadowaki, Takeshi Yamamoto. IL-6 contributes to the interaction between enteric nervous system and mucosal immune system. CYTOKINE. 2017. 100. 128-128
  • 長田夕佳, 山本武, 門脇真. 食物アレルギーモデルに対する葛根湯と経口免疫療法の併用によるレチノイン酸代謝を介した制御性T細胞誘導. アレルギー. 2017. 66. 4/5. 736-736
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Lectures and oral presentations  (5)：
  • 制御性 T 細胞誘導薬を経口免疫療法に併用した食物アレルギーの新たな治療法の開発
    (日本薬学会北陸支部 第130回例会 2018)
  • Therapeutic effect and preventive effect of kakkonto on food allergy
    (2018 CAP Sikchi symposium, The Relationship between Medicinal Food and Nutrition in Health Care 2018)
  • 葛根湯の制御性T細胞誘導作用を活用した食物アレルギーの新規治療法の開発研究
    (第35回和漢医薬学会学術大会 2018)
  • 食物アレルギーの根本的治療の確立を目指した葛根湯を併用した経口免疫療法の検討
    (フォーラム富山「創薬」 2018)
  • マウス食物アレルギー病態モデルを用いて新たに見出した 葛根湯併用経口免疫療法の根本的治療法としての提案
    (第65回日本実験動物学会総会 2018)
Education (2)：
  • University of Shizuoka Graduate School of Nutritional and Environmental Sciences
  • University of Shizuoka Graduate School, Division of Nutritional and Environmental Scieces
Professional career (1)：
  • (BLANK)
Work history (5)：
  • 2023/04 - 現在 Kanazawa Gakuin University
  • 2007/04 - 2023/03 University of Toyama Institute of Natural Medicine
  • 2005/10 - 2007/03 University of Toyama Institute of Natural Medicine
  • 2004/09 - 2005/09 Toyama Medical and Pharmaceutical University
  • 1999/03 - 2004/08 Siebold University of Nagasaki Faculty of Nursing and Nutrition
Awards (1)：
  • 2018/09 - 和漢医薬学会 学術貢献賞 葛根湯の制御性T細胞誘導作用を活用した食物アレルギーの新規治療法の開発研究
Association Membership(s) (5)：
THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  JAPANESE SOCIETY OF ALLERGOLOGY ,  MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU ,  日本消化吸収学会 ,  日本生理学会
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