Rchr
J-GLOBAL ID：200901090767891285   Update date: Oct. 04, 2023

Hachisu Masakazu

ハチス マサカズ | Hachisu Masakazu
Affiliation and department：
National Institute of Technology,Tsuruoka College Department of Creative Engineering

About National Institute of Technology,Tsuruoka College Department of Creative Engineering


Job title： Junior Associate Professor
Homepage URL  (2)： https://www.tsuruoka-nct.ac.jp/gakka/souzou/cb/ ,  https://www.tsuruoka-nct.ac.jp/en/faculty/department-of-chemical-and-biological-engineering/
Research field  (3)： Bioorganic chemistry ,  Applied biochemistry ,  Polymer materials
Research keywords  (6)： Immunoregulatory molecule ,  Biopolymer ,  Glycoconjugate ,  Carbohydrate ,  Amino acid ,  Lipid
Research theme for competitive and other funds  (3)：
  • 2023 - 2026 Regulation of mast cell activation and immune tolerance by food-related factors focusing on short-chain fatty acid
  • 2021 - 2024 スルファチド類縁体の構造活性相関研究:新規作用機序インフルエンザ薬創製の基盤構築
  • 2015 - 2017 Systematic chemical synthesis and structure-function analysis of glycosylated collagens
Papers (33)：
  • Kazuki Nagata, Sanae Araumi, Daisuke Ando, Naoto Ito, Miki Ando, Yuki Ikeda, Miki Takahashi, Sakura Noguchi, Yayoi Yasuda, Nobuhiro Nakano, et al. Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcεRI and SHIP1. International Journal of Molecular Sciences. 2023. 24. 6. 5997
  • Miki Ando, Kazuki Nagata, Naoto Ito, Sakura Noguchi, Asuka Yamamoto, Naoki Kodama, Takuya Yashiro, Masakazu Hachisu, Gaku Ichihara, Shigenobu Kishino, et al. The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling. bioRxiv. 2023
  • Naoki Kodama, Hikaru Okada, Masakazu Hachisu, Miki Ando, Naoto Ito, Kazuki Nagata, Mayuka Katagiri, Yayoi Yasuda, Ikumi Hiroki, Takuya Yashiro, et al. A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice. Frontiers in Nutrition. 2023. 10. 1081263
  • Tsubasa Ashikari, Masakazu Hachisu, Kazuki Nagata, Daisuke Ando, Yuki Iizuka, Naoto Ito, Kandai Ito, Yuki Ikeda, Hiroki Matsubara, Takuya Yashiro, et al. Salicylaldehyde Suppresses IgE-Mediated Activation of Mast Cells and Ameliorates Anaphylaxis in Mice. International Journal of Molecular Sciences. 2022. 23. 15. 8826
  • Naoto Ito, Fumiya Sakata, Masakazu Hachisu, Kazuki Nagata, Tomoka Ito, Kurumi Nomura, Masanori Nagaoka, Keito Inaba, Mutsuko Hara, Nobuhiro Nakano, et al. The Ccl17 gene encoding TARC is synergistically transactivated by PU.1 and IRF4 driven by the mammalian common promoter in dendritic cells. Allergy. 2022. 77. 3. 1054-1059
ｍore...
MISC (14)：
  • 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 小竹ひとみ, 西山千春, 清水公徳. Growth of Basidiomycete Yeast Isolated from Parmotrema Tinctorum Is Inhibited by Extracts of Parmotrema Tinctorum. Lichenology. 2023. 21. 2. 62
  • 西山 千春, 岡田 光, 兒玉 直輝, 安藤 実希, 伊藤 直人, 長田 和樹, 八須 匡和. 薔薇香気成分の免疫調節作用 ~スクリーニングにより選抜された薔薇香気主成分β-ダマスコン~. Aroma research. 2023. 24. 1. 53-55
  • The effects of salicylaldehyde on IgE-mediated activation of mast cells in vivo and in vitro. 2023. 24. 1. 17-19
  • 永田彩奈, 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 西山千春, 清水公徳. Search for Antifungal Substances Produced by Parmotrema Tinctorum. Lichenology. 2022. 20. 2. 63
  • 平野敦春, 八須匡和, NGUYEN Ngoc Hung, NGUYEN Phuong Thao, 小竹ひとみ, 西山千春, 清水公徳. Growth of Basidiomycete Yeast Isolated from Cladonia Rei Is Inhibited by Extracts of Parmotrema Tinctorum. Lichenology. 2022. 20. 2. 63
ｍore...
Patents (2)：
Books (1)：
  • 相分離生物学の全貌(現代化学増刊46), 白木賢太郎 編
    東京化学同人 2020 ISBN:9784807913466
Lectures and oral presentations  (114)：
  • NR4A3欠損マウスでは樹状細胞上のTLR8発現が亢進し乾癬が悪化する
    (日本農芸化学会2023年度大会 2023)
  • 樹状細胞における短鎖脂肪酸を介したインテグリン遺伝子転写活性化の分子機構
    (日本農芸化学会2023年度大会 2023)
  • 多価不飽和脂肪酸腸内乳酸菌代謝産物γKetoCはNRF3経路を介して炎症性腸疾患を緩和する
    (日本農芸化学会2023年度大会 2023)
  • 短鎖脂肪酸とニコチン酸はGPR109A-PGE2-EP4経路を介してIgE依存性マスト細胞活性化を抑制する
    (日本農芸化学会2023年度大会 2023)
  • Molecular mechanisms of short-chain fatty acids-mediated transactivation ofintegrin genes in dendritic cells
    (第51回日本免疫学会学術集会 2022)
ｍore...
Education (3)：
  • 2004 - 2008 Hokkaido University Graduate School of Science Division of Biological Sciences
  • 2002 - 2004 Shinshu University Graduate School of Engineering Department of Functional Polymer Science
  • 1998 - 2002 Shinshu University Faculty of Textile Science and Technology Functional Polymer Science Course
Professional career (3)：
  • Doctor of Philosophy (Hokkaido University)
  • Master of Engineering (Shinshu University)
  • Bachelor of Engineering (Shinshu University)
Work history (6)：
  • 2023/04 - 現在 National Institute of Technology,Tsuruoka College Department of Creative Engineering
  • 2021/04 - 2023/03 Tokyo University of Science Faculty of Advanced Engineering, Department of Biological Science and Technology
  • 2015/04 - 2021/03 Tokyo University of Science Faculty of Industrial Science and Technology, Department of Biological Science and Technology
  • 2010/04 - 2015/03 ERATO, The Japan Science and Technology Agency (JST) Ito Glycotrilogy Project
  • 2009/04 - 2010/03 National Institute of Advanced Industrial Science and Technology (AIST) Research Institute of Genome-based Biofactory
Show all
Committee career (1)：
  • 2011/04 - 2019/03 グライコサイエンス若手の会 世話人
Awards (1)：
  • 2016/11 - GlycoTOKYO Encouraging Prize Chemical approaches to probe the mechanism of
Association Membership(s) (6)：
Japanese Association for Food Immunology ,  Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  The Chemical Society of Japan ,  Forum: Carbohydrates Coming of Age ,  The Japanese Society of Carbohydrate Research ,  The Society of Polymer Science, Japan
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